Synonyms Carcinoma, Embryonal, Carcinomas, Embryonal, Embryonal Carcinoma + [18] |
Introduction A highly malignant, primitive form of carcinoma, probably of germinal cell or teratomatous derivation, usually arising in a gonad and rarely in other sites. It is rare in the female ovary, but in the male it accounts for 20% of all testicular tumors. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, p1595) |
Target |
Mechanism Top II inhibitors |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication- |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. US |
First Approval Date17 May 1996 |
Target- |
Mechanism DNA synthesis inhibitors |
Active Org. |
Originator Org. |
Inactive Indication- |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. JP |
First Approval Date16 Dec 1968 |
Target |
Mechanism Tubulin inhibitors [+1] |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication- |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc.- |
First Approval Date01 Jan 1961 |
Start Date12 Apr 2023 |
Sponsor / Collaborator |
Start Date13 Jul 2021 |
Sponsor / Collaborator |
Start Date25 May 2017 |
Sponsor / Collaborator |