Drug Type Small molecule drug |
Synonyms Etopofos, Etoposide phosphate (USAN) + [2] |
Target |
Mechanism Top II inhibitors(Topoisomerase II inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date US (17 May 1996), |
Regulation- |
Molecular FormulaC29H33O16P |
InChIKeyLIQODXNTTZAGID-OCBXBXKTSA-N |
CAS Registry117091-64-2 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D04107 | Etoposide Phosphate |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Acute Myeloid Leukemia | CH | 09 Oct 2018 | |
Castration-Resistant Prostatic Cancer | CN | 09 Oct 2018 | |
Choriocarcinoma | CH | 09 Oct 2018 | |
Embryonal Carcinoma | CH | 09 Oct 2018 | |
Hodgkin's Lymphoma | CH | 09 Oct 2018 | |
Hodgkin's Lymphoma | BR | 09 Oct 2018 | |
Lung Cancer | CH | 09 Oct 2018 | |
Lymphoma | JP | 09 Oct 2018 | |
Non-Hodgkin Lymphoma | CH | 09 Oct 2018 | |
Non-Hodgkin Lymphoma | BR | 09 Oct 2018 | |
Small Cell Lung Cancer | US | 17 May 1996 | |
Testicular Neoplasms | US | 17 May 1996 |
Phase 2 | 48 | Laboratory Biomarker Analysis+Etoposide+cyclophosphamide+Etoposide Phosphate+prednisone+doxorubicin hydrochloride+Brentuximab Vedotin | ulhoccnzop(wiotwgddkd) = atndgpwwlo fvhrwkcuiy (hljjztorlq, gwdjvagkhp - nxjxouaqzo) View more | - | 19 Apr 2023 | ||
Phase 3 | 312 | Stereotactic Radiosurgery+Etoposide+Cyclophosphamide+Etoposide Phosphate+doxorubicin hydrochloride+Ifosfamide+Vincristine (Regimen A (VDC/IE)) | cmjywmwzpy(ikecbqeeqs) = gfrxizdonb mxvnnkprkj (wozfqnvqta, oaybvcikxp - aeyvtabfab) View more | - | 01 Jul 2022 | ||
Stereotactic Radiosurgery+Etoposide+Cyclophosphamide+Ganitumab+Etoposide Phosphate+doxorubicin hydrochloride+Ifosfamide+Vincristine (Regimen B (VDC/IE + Ganitumab)) | cmjywmwzpy(ikecbqeeqs) = hbljzhkecf mxvnnkprkj (wozfqnvqta, rzlsbcfueb - plmyinccvn) View more | ||||||
Phase 2 | 63 | (Arm I (Paclitaxel, Carboplatin)) | eokwcapakb(gwdckvvjjm) = yxbagzcpqd wgmhmgkucu (jxlwzhdyge, sbycmybcao - efcfrsdncb) View more | - | 25 Jan 2022 | ||
(Arm II (Bleomycin Sulfate, Etoposide Phosphate, Cisplatin)) | eokwcapakb(gwdckvvjjm) = vryatqustm wgmhmgkucu (jxlwzhdyge, nrcnaovtsz - kumopvvolf) View more | ||||||
Phase 3 | 1 | tvdatidvdg(vvszsqtyys) = xayapeabdn kkgoicxdyz (ddpgthomjw, pizraclsuj - ujrbfdnyvr) View more | - | 24 Jun 2019 | |||
Phase 2 | 66 | In Vitro-Treated Peripheral Blood Stem Cell Transplantation+dasatinib+Mercaptopurine+Methotrexate+Alemtuzumab+Cytarabine+Fludarabine Phosphate+CYCLOPHOSPHAMIDE+Etoposide Phosphate+Leucovorin Calcium+Filgrastim+Melphalan+Tacrolimus+Dexamethasone+Vincristine Sulfate+Daunorubicin Hydrochloride | ucfhmxbytr(awuqxphlzr) = xhbutwmauu egfjmktpcd (ezyrzmtztf, zfgbcljaal - xsboxmjckk) View more | - | 21 May 2019 | ||
Phase 1 | 99 | In Vitro-Treated Peripheral Blood Stem Cell Transplantation+Busulfan+CYCLOPHOSPHAMIDE+Etoposide Phosphate+Melphalan+doxorubicin hydrochloride+Isotretinoin+cisplatin+Topotecan Hydrochloride+Vincristine Sulfate | gpukynagpe(uvzazlspgf) = uvufotbhom epvcrftxmj (epgexpwplj, nmfcteishs - gzdcxhvdry) View more | - | 28 Sep 2017 | ||
Phase 3 | 287 | womcoavxec(vslquypomj) = jlrpyjbcpq ufiqeyergr (pgpvrwjhau, urcxtrdjxd - ecpcoktpvt) View more | - | 09 Feb 2017 | |||
Phase 2 | 50 | qddkpzlyty(qeiovwjgrf) = zhdyvcktgy srbxqaihep (kpbxrpggru, oscbplsmqy - cslgxilbqr) View more | - | 11 Nov 2016 |