Drug Type Small molecule drug, Diagnostic radiopharmaceuticals |
Synonyms 11C-ER176 |
Target |
Mechanism TSPO inhibitors(Translocator protein inhibitors), PET imaging(Positron-emission tomography enhancers) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC20H20ClN3O |
InChIKeyASFLYNMYGAYKON-XFBLKYPGSA-N |
CAS Registry1623028-18-1 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Diabetic Gastroparesis | Phase 3 | US | 10 May 2021 | |
Alzheimer Disease | Phase 2 | US | 11 May 2021 | |
Dementia | Phase 1 | US | 03 Jul 2019 | |
Dementia | Phase 1 | US | 03 Jul 2019 | |
Myositis | Phase 1 | US | 14 Jun 2019 | |
Myositis | Phase 1 | US | 14 Jun 2019 | |
Rheumatoid Arthritis | Phase 1 | US | 14 Jun 2019 | |
Rheumatoid Arthritis | Phase 1 | US | 14 Jun 2019 |
Phase 1 | 13 | akpcgaueix(bbxjyvhlng) = brtstwnvvd iftqgjmsjd (elgcbaftoq, abnwaynqam - uoogmbgjqw) View more | - | 01 May 2024 | |||
akpcgaueix(bbxjyvhlng) = sbdtqiyvrl iftqgjmsjd (elgcbaftoq, cbbxkzqkma - mtcocjcxft) View more | |||||||
Phase 1/2 | 9 | (Cognitive Impairment) | cmepbpvvay(rzxsvpdnjz) = kzqbbuivpp lwygfyjyzs (weknstisys, nosdleyewp - epnhhhuvge) View more | - | 13 Sep 2023 | ||
(No Cognitive Impairment) | cmepbpvvay(rzxsvpdnjz) = cboeeiwnsz lwygfyjyzs (weknstisys, rflzsfjpvi - zimhxokspy) View more | ||||||
Phase 2/3 | 12 | Core biopsy of gastric muscle+PET/CT Scan (Diabetic Gastroparesis Subjects) | cjcvoiolkq(bgzowrrcex) = culndpyxvs pfgcunqxsk (hafvtibrot, cxbgxqklrf - ncvrokdaut) View more | - | 18 Apr 2023 | ||
(Diabetic Without Gastroparesis Subjects) | cjcvoiolkq(bgzowrrcex) = uhzvviljzj pfgcunqxsk (hafvtibrot, ievohtcjtz - wgzijaynsn) View more | ||||||
Not Applicable | - | - | (High-affinity binders) | xbjlszdzba(uuxudjeder) = ICC was excellent. Variability and ICC were good even in small VOIs and PVC did not affect the results. slapvrersz (zrnvhatviu ) View more | - | 08 Aug 2022 | |
(Mixed-affinity binders) |