Drug Type Fab fragment |
Synonyms anti-MSLN-PE24-cFP, LMB 100, LMB100 + [4] |
Target |
Action inhibitors |
Mechanism MSLN inhibitors(Mesothelin inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Adenocarcinoma of Lung | Phase 2 | United States | 11 Sep 2019 | |
Squamous non-small cell lung cancer | Phase 2 | United States | 11 Sep 2019 | |
Malignant Mesothelioma of Peritoneum | Phase 2 | United States | 04 Dec 2018 | |
Mesothelin positive Solid Tumors | Phase 2 | United States | 03 Aug 2016 | |
Metastatic Pancreatic Ductal Adenocarcinoma | Phase 2 | United States | 03 Aug 2016 | |
Mesothelioma | Phase 2 | - | - | |
Mesothelioma | Phase 2 | - | - | |
Malignant Pleural Effusion | Phase 1 | United States | 31 Jan 2024 | |
Malignant Pleural Mesothelioma | Phase 1 | United States | 31 Jan 2024 | |
Pancreatic Ductal Carcinoma | Phase 1 | United States | 31 Jan 2024 |
Phase 1 | 21 | (All Participants) | bzbkezlkfh = sogtyokcut purxncqjer (qiatkfholk, wtvwsnjrnk - jkdqhzigwk) View more | - | 23 Aug 2022 | ||
(Dose Level -1: 140mcg LMB-100) | ptqypqimpz = ghsgzfyvvv ozkcafdlcf (trbareukto, bdgbvwjonr - xqnuwmxqiq) View more | ||||||
Phase 2 | 18 | npsjyqubqu = ntacxjurzc eyyvyiwguh (tfzstuthaf, qatlctgtbi - aoatqtejqr) View more | - | 02 Dec 2021 | |||
Phase 1 | 13 | voyipyhqro(mchvozpuop) = Of the 8 patients who received two cycles of treatment at MTD, 4 met prespecified criteria for ADA prevention, and 2 patients who went on ~ receive cycle 3 had detectable LMB-100 plasma drug levels after administration uufbvyduok (vcrlplpcha ) View more | Negative | 22 Jan 2021 | |||
Phase 1/2 | 20 | ibzmhxpyqg(veacopfwtg) = fhlymttyyr mxkmmmvvba (rgiscvmbnw ) View more | Negative | 15 Feb 2020 | |||
Phase 2 | 18 | vgqbtyywep(yvvnfphezf) = ynxccgyzqr fzxvazdvhb (vfreafyrft ) View more | - | 09 Sep 2019 | |||
Phase 1 | Neoplasms human mesothelin | - | RG7787 + anti CTLA4 | jotgkrmtlo(bgzyysgyck) = vzwvwdbuwj twyuiluwaw (pwsatqqhlf ) | Positive | 04 Nov 2015 | |
anti CTLA4 | jotgkrmtlo(bgzyysgyck) = ouzshxnxss twyuiluwaw (pwsatqqhlf ) |