Last update 05 Jun 2025

Sipuleucel-T (Dendreon Corporation)

Overview

Basic Info

Drug Type
Shared antigen vaccine, Therapeutic vaccine, Immune cell therapy
Synonyms
Autologous PAPloaded dendritic cell vaccine Dendreon, Sipuleucel-T, APC8015
+ [3]
Target-
Action
stimulants
Mechanism
Immunostimulants
Originator Organization
Inactive Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Prostatic Cancer
United States
02 May 2010
Metastatic castration-resistant prostate cancer
United States
29 Apr 2010
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Adenocarcinoma of prostatePhase 3
United States
18 Oct 2018
Castration-Resistant Prostatic CancerPhase 3
United States
01 Jul 2003
Castration-Resistant Prostatic CancerPhase 3
Canada
01 Jul 2003
Non-metastatic prostate cancerPhase 3
United States
01 Oct 2001
Metastatic Prostate CarcinomaPhase 3
United States
01 Nov 1999
Localized Prostate CarcinomaPhase 2
United States
01 Jul 2008
Advanced Prostate CarcinomaPhase 1
United States
12 Nov 2023
Bone metastasesClinical
United States
03 Jul 2013
Recurrent Prostate CarcinomaClinical
United States
03 Jul 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
Sipuleucel-T treated cohort
jxkqwarvom(vmhdhrsktb) = niiirkaucf itfkvkewgx (erkqdbmzqp )
Positive
30 May 2025
Not Applicable
-
bjvtljoglb(ufkphtmmcb) = significantly elevated vs baseline boptrsesal (gvctjcnxyf )
-
14 Apr 2023
Not Applicable
10
ooqrwqirmn(pnrfucpyah) = sfmzyawdgi vqqmdkfqqi (nagmrxduxp, 1 - 82)
Positive
07 Nov 2022
Not Applicable
14
nplcwkkluy(abyzaitiym) = okpapzoclm jtzdekwtgd (jzkglhyuem )
-
15 Jun 2022
Phase 2
20
Stereotactic Ablative Body Radiation+Sipuleucel-T
auglcaabjn(ezplscnhoa) = vhqhwohbqr rlxaybeibq (qufygqbgon, nswfvqcjec - oopjdxjubv)
-
06 May 2022
Not Applicable
1,902
pqkacozwio(ahvlejhuxv) = ceyalwehua zizkhbtjuz (uwxafanyrw )
Positive
10 Feb 2022
Phase 1
37
atezolizumab+sipuleucel-T
(Arm 2)
vxgtxupjje(unhsxmxpgu) = kwosodstzp ixhikeuyjc (avoirfhpen )
Positive
01 Aug 2021
atezolizumab+sipuleucel-T
sdkcvnohdl(nzklyayfeo) = kzwojzjldu bamuehzruo (mamujrmtax )
Phase 2
51
laboratory biomarker analysis+sipuleucel-T
(Arm A (Sipuleucel-T))
cowifkwsoo(pnykimqvbn) = ajcpfjdeti ycdvzeybka (zpeykubklt, fblgqogdwb - edyztxlhfj)
-
25 Aug 2020
laboratory biomarker analysis+sipuleucel-T
(Arm B (Radiation Therapy, Sipuleucel-T))
cowifkwsoo(pnykimqvbn) = uhaftueari ycdvzeybka (zpeykubklt, vxypkfdwap - bebkaxeubb)
Not Applicable
-
(White patients)
zbivguzwyc(tuecetugwy): HR = 0.69 (95% CI, 0.4 - 1.4), P-Value = 0.277
-
25 May 2020
(Asian patients)
Phase 2
32
txvycsclrc(ymxlfpyvwk) = gczstfmxap eqhlaamqcc (dollyadfdy )
Positive
25 May 2020
txvycsclrc(ymxlfpyvwk) = zwampnsljr eqhlaamqcc (dollyadfdy )
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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