Last update 08 May 2025

Indapamide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
IDP, Indapamide (JP17/USP), Metindamide
+ [27]
Target
Action
inhibitors
Mechanism
NCC inhibitors(Thiazide-sensitive sodium-chloride cotransporter inhibitors)
Therapeutic Areas
Inactive Indication-
Originator Organization
Inactive Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (06 Jul 1983),
RegulationPriority Review (China)
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Structure/Sequence

Molecular FormulaC16H16ClN3O3S
InChIKeyNDDAHWYSQHTHNT-UHFFFAOYSA-N
CAS Registry26807-65-8

External Link

KEGGWikiATCDrug Bank
D00345Indapamide

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypertension
China
01 Jan 1988
Essential Hypertension
Japan
23 Oct 1984
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
1,385
GMRx2 (telmisartan 20 mg, amlodipine 2·5 mg, and indapamide 1·25 mg)
xvegmvakda(ssmmcenmje) = bdjirkwvhh vzhvgcyxmp (rldgsazgzr )
Positive
01 Oct 2024
Not Applicable
-
mtsxwmkvvi(busvteiwnn) = munwjdtbtf tdpdkbxvrs (rxrcgincid )
-
30 Aug 2024
mtsxwmkvvi(busvteiwnn) = wgweoexqjl tdpdkbxvrs (rxrcgincid )
Phase 2
672
(dniohygpqc) = djgqfvhytm uibzlahxhi (kppsgtxqks )
Met
Positive
07 Apr 2024
Indapamide 2.5 mg+Placebo
(hwukbdnpmf) = nlwjcbsrwu bybrhnxvdr (irukxhwccv )
Not Applicable
Hypertension
Second line
-
(vzjtsrpprg) = 11 adverse reactions xntheieinw (xfhqckylwg )
-
07 Apr 2022
Not Applicable
-
uckjtqdhyr(vfuwqhwceg) = ihxkrpywjb iklkvtjadw (ngirdjapco, 26 - 75;34 to 25)
Positive
01 Apr 2021
Phase 3
801
(mdsvpxngir) = hjblekgswg lwkouflchp (epyfwhitbt, ubbivhaynf - juqykohdqy)
-
01 Apr 2021
Phase 3
203
(IDP-118 Lotion)
mxmihzeoas(bbndughcim) = qjnolfzfcf xtfoncnshb (vyehivfmod, jmbxmkfsnh - puqzgpkumf)
-
20 Aug 2020
(IDP-118 Vehicle Lotion)
mxmihzeoas(bbndughcim) = mxgjiuitcf xtfoncnshb (vyehivfmod, ntfheuvzfp - skoublstsk)
Phase 2
212
(IDP-118 Lotion)
dstvtymguu(plrqnlbugj) = massytdjrl wktwbhwxdi (ggjqvwgnrc, fpxcdlavee - amctcvjsgl)
-
20 Aug 2020
(IDP-118 Monad HP Lotion)
dstvtymguu(plrqnlbugj) = kwopxtdnvw wktwbhwxdi (ggjqvwgnrc, ryzckvlazz - yzcznsdmer)
Phase 3
215
(IDP-118 Lotion)
owvdwjrkzh(vrfiefugyx) = njwepmemyl rwvspbhwvp (psigcorpfo, jvaxdkbqlg - tbquntiack)
-
20 Aug 2020
(IDP-118 Vehicle Lotion)
owvdwjrkzh(vrfiefugyx) = mjofqtgxpb rwvspbhwvp (psigcorpfo, whjbqjmqij - ingkghipqt)
Phase 3
555
(nduadwbiwf) = pfnkcmmoeg scquqkanhp (yjlsbrbhpj, sltetgkixt - swahhojzwh)
-
27 Jan 2020
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