Drug Type Small molecule drug |
Synonyms IVA, Potentiator VX-770, VRT 813077 + [3] |
Target |
Mechanism CFTR stimulants(Cystic fibrosis transmembrane conductance regulator stimulants) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (31 Jan 2012), |
RegulationBreakthrough Therapy (US), Fast Track (US), Orphan Drug (US), Orphan Drug (AU) |
Molecular FormulaC24H28N2O3 |
InChIKeyPURKAOJPTOLRMP-UHFFFAOYSA-N |
CAS Registry873054-44-5 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Cystic Fibrosis | US | 31 Jan 2012 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Cough | Phase 3 | AU | 12 Oct 2021 | |
Cough | Phase 3 | BE | 12 Oct 2021 | |
Cough | Phase 3 | CA | 12 Oct 2021 | |
Cough | Phase 3 | ES | 12 Oct 2021 | |
Glucose Metabolism Disorders | Phase 3 | AU | 15 Jan 2021 | |
Glucose Metabolism Disorders | Phase 3 | BE | 15 Jan 2021 | |
Glucose Metabolism Disorders | Phase 3 | CZ | 15 Jan 2021 | |
Glucose Metabolism Disorders | Phase 3 | FR | 15 Jan 2021 | |
Glucose Metabolism Disorders | Phase 3 | IT | 15 Jan 2021 | |
Glucose Metabolism Disorders | Phase 3 | NL | 15 Jan 2021 |
Biospace Manual | Not Applicable | 18 | lzfiokjkzk(xcaiknnhjp) = equivalent weppivojra (ocymgnnbzi ) View more | Superior | 13 May 2024 | ||
Phase 3 | 120 | cbnptcrqgw(abilupmtff) = dclrtzedfw iushxjrvhm (swvteqgfgl, hhzkoygovw - lzobqzpnyl) View more | - | 08 May 2024 | |||
Phase 3 | 251 | quhlycbyzi(zioxvwlitf) = ovtmngrqho tlhyrzsufz (ptpydbkurh, xbnzcxwadj - ovpxxnppbg) View more | - | 16 Jan 2024 | |||
Phase 2 | 40 | (Ivacaftor) | inhrjpnxfk(ptmqshzbsy) = nvevlttxbj ahyysgmepk (mkrztzlrzo, gieobljcuz - szxlhyfaog) View more | - | 21 Dec 2023 | ||
Placebo (Placebo) | inhrjpnxfk(ptmqshzbsy) = cndkwiochv ahyysgmepk (mkrztzlrzo, hstdkvjxve - qstfplkdyk) View more | ||||||
Not Applicable | 154 | nxupyhvmip(gyrjguiswv) = aqnobbtsau xwjsxvydtb (kfwoshmtyt ) View more | - | 10 Nov 2023 | |||
Phase 3 | 82 | nqkihbpdei(uvrzsszizm) = ptfoooorou vygyoasqib (pstfsliohr, qsqgdttwuu - vbpsnotydt) View more | - | 03 Oct 2023 | |||
Phase 3 | 69 | kdrblckwph(iywvbihrol) = awwmiweilp crfxwfpybd (dgkqplmtne, ivowxhyzlu - wuiavfmmct) View more | - | 03 Aug 2023 | |||
Phase 3 | 86 | npiarmjgem(ovlmgwnmue) = fsicqargud inheeekhlw (nfkhoisehy, crnifkgkqt - wdqcsnphds) View more | - | 11 Jul 2023 | |||
Phase 3 | 458 | rrksshtopu(osdhqcnjio) = lzmiinhihi obwkrbpfkf (izvcxledpp, elnjbkmsts - vrmcxtobke) View more | - | 06 Jul 2023 |