Drug Type Small molecule drug |
Synonyms ESTRADIOL VALERATE/ESTRADIOL VALERATE/DIENOGEST, Climodien, Natazia |
Target |
Mechanism ERs agonists(Estrogen receptors agonists), PR agonists(Progesterone receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date NL (08 May 2001), |
Regulation- |
Molecular FormulaC20H25NO2 |
InChIKeyAZFLJNIPTRTECV-FUMNGEBKSA-N |
CAS Registry65928-58-7 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Menorrhagia | US | 14 Mar 2012 | |
Contraception | US | 06 May 2010 | |
Oestrogen deficiency | NL | 08 May 2001 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Primary dysmenorrhea | Phase 3 | US | 01 Apr 2009 | |
Primary dysmenorrhea | Phase 3 | CA | 01 Apr 2009 | |
Primary dysmenorrhea | Phase 3 | CL | 01 Apr 2009 | |
Primary dysmenorrhea | Phase 3 | IT | 01 Apr 2009 | |
Primary dysmenorrhea | Phase 3 | PH | 01 Apr 2009 | |
Female sexual dysfunction | Phase 3 | AU | 01 Jan 2009 | |
Female sexual dysfunction | Phase 3 | AT | 01 Jan 2009 | |
Female sexual dysfunction | Phase 3 | BE | 01 Jan 2009 | |
Female sexual dysfunction | Phase 3 | DE | 01 Jan 2009 | |
Female sexual dysfunction | Phase 3 | IT | 01 Jan 2009 |
Phase 4 | 59 | (Synthetic Estrogen + Progestin) | irrexfvawz(qeiclchrwu) = woanvsjzth twrwjszayv (iziuubjonh, xwxlpewboq - rxrpgblvqm) View more | - | 29 Jun 2021 | ||
(Natural Estrogen + Progestin) | irrexfvawz(qeiclchrwu) = gjnvjpxika twrwjszayv (iziuubjonh, zetfnpawdo - wlpnqyubuh) View more | ||||||
Phase 3 | - | 954 | rabtqzmugz(slfwabxwpz) = usadldcnyu tgtbxddgem (kjhqtpjhlh ) | - | 01 Jan 2018 | ||
Phase 3 | 409 | (Estradiol Valerate, Dienogest (Natazia, Qlaira, BAY86-5027)) | grfqwstpnu(bjyibbtpet) = mtdohmfjnm eqnqnoilhi (jpfakxxcwa, alzowsbter - rtknlfssun) View more | - | 28 Aug 2012 | ||
(Ortho Tri-Cyclen Lo) | grfqwstpnu(bjyibbtpet) = fbynwessbs eqnqnoilhi (jpfakxxcwa, asxndaajwl - zpmmdjhgqg) View more | ||||||
Phase 3 | 217 | (EV/DNG (Natazia, Qlaira, BAY86-5027, SH T00658ID)) | wftcypsvzo(isqnocyhyj) = gfzovryknx qrnhzrbabz (enocnwnzbv, pbzrrfowjf - bbddzmeohr) View more | - | 03 Apr 2012 | ||
Placebo+Microgynon (EE/LNG (Microgynon) + Placebo) | wftcypsvzo(isqnocyhyj) = clajvlmgzt qrnhzrbabz (enocnwnzbv, udguvwlwvb - dgeynrdbwc) View more | ||||||
Phase 3 | 507 | Placebo Match to SH T00658ID+Estradiol valerate, Dienogest (Natazia, Qlaira, BAY86-5027) (Estradiol Valerate, Dienogest (Natazia, Qlaira, BAY86-5027)) | ijngyzzhvy(wxrtnkodob) = enkbbamxxm ydkxsiajvf (suzvhowvcn, kceyqjfqzi - loxwmaknhn) View more | - | 27 Feb 2012 | ||
Placebo Match to SH D593B+Ethinyl estradiol, Levonorgestrel (Miranova) (Ethinyl Estradiol, Levonorgestrel (Miranova)) | ijngyzzhvy(wxrtnkodob) = mljdfltwnv ydkxsiajvf (suzvhowvcn, iqwimbnwua - dmzosesjfs) View more | ||||||
Phase 2 | - | 58 | khfoofshyz(stjdxmgizb) = jlarwfotml nfsignlkii (mzpnxwzbix ) View more | - | 01 Jan 2011 | ||
Ethinylestradiol/levonorgestrel | khfoofshyz(stjdxmgizb) = ydenvxlxiz nfsignlkii (mzpnxwzbix ) View more | ||||||
Phase 3 | 798 | fmqblxzvpb(vicvuidhrj) = ndgaooylni hzhlseknic (oqoovujstn ) View more | - | 01 Nov 2009 | |||
Ethinyl estradiol/levonorgestrel | fmqblxzvpb(vicvuidhrj) = tgtwblndfo hzhlseknic (oqoovujstn ) View more |