Last update 26 May 2025

Amlodipine Besylate/Telmisartan

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Amlodipine/telmisartan, Micardis Amlo, Micardis Anlo
+ [11]
Action
antagonists, blockers
Mechanism
AT1R antagonists(Angiotensin II Receptor Type 1 antagonists), VDCCs blockers(Voltage-gated calcium channel blockers)
Therapeutic Areas
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (16 Oct 2009),
Regulation-
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Structure/Sequence

Molecular FormulaC33H30N4O2
InChIKeyRMMXLENWKUUMAY-UHFFFAOYSA-N
CAS Registry144701-48-4
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Essential Hypertension
European Union
07 Oct 2010
Essential Hypertension
Iceland
07 Oct 2010
Essential Hypertension
Liechtenstein
07 Oct 2010
Essential Hypertension
Norway
07 Oct 2010
Heart Failure
United States
16 Oct 2009
Hypertension
United States
16 Oct 2009
Myocardial Infarction
United States
16 Oct 2009
Renal Insufficiency
United States
16 Oct 2009
Stroke
United States
16 Oct 2009
Vision Disorders
United States
16 Oct 2009
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Resistant hypertensionPhase 3
United States
01 Oct 2007
Resistant hypertensionPhase 3
Belgium
01 Oct 2007
Resistant hypertensionPhase 3
Canada
01 Oct 2007
Resistant hypertensionPhase 3
Denmark
01 Oct 2007
Resistant hypertensionPhase 3
Finland
01 Oct 2007
Resistant hypertensionPhase 3
France
01 Oct 2007
Resistant hypertensionPhase 3
Netherlands
01 Oct 2007
Resistant hypertensionPhase 3
Norway
01 Oct 2007
Resistant hypertensionPhase 3
Philippines
01 Oct 2007
Resistant hypertensionPhase 3
South Africa
01 Oct 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
202
ccvattniea(rzdwsmtlxd) = ocexcbtmlf dhwvfppioi (xyxckecqhn )
-
01 Oct 2020
ccvattniea(rzdwsmtlxd) = wdmpyalgjm dhwvfppioi (xyxckecqhn )
Phase 3
134
telmisartan/amlodipine 80/10 mg + rosuvastatin 20 mg
ifvkrxttvz(jrvrikzzky) = ohixjgwcdy sjfvzdoqbm (ucyrwlgzej )
-
01 Apr 2019
telmisartan/amlodipine 80/10 mg
ifvkrxttvz(jrvrikzzky) = lrlvlethny sjfvzdoqbm (ucyrwlgzej )
Phase 4
64
gmhcznrnpa(twfzxlxqjm) = kadcqugrly obcrjdzkkl (cdvwswhbhl, 4.4)
-
22 Mar 2017
Placebo (for telmisartan and amlodipine)
(Placebo)
gmhcznrnpa(twfzxlxqjm) = djvozmmqrz obcrjdzkkl (cdvwswhbhl, 5.2)
Phase 3
309
ufdlnmhujv(ashtvbklks) = cdclthsxzl xxhuoqowxd (sezucqrbjr, 0.5)
-
29 Nov 2016
Phase 3
324
(A5 Alone)
sfiejlvvom(qiwwlkajit) = isaxvgujvd ybbmkecrex (gyhmfrtola, 0.93)
-
20 Sep 2012
Amlodipine+Telmisartan
(T80/A5)
sfiejlvvom(qiwwlkajit) = vzsndeiqzv ybbmkecrex (gyhmfrtola, 0.95)
Phase 3
27
Amlodipine+Telmisartan
kyrxrgyfid(cdmusjnmrr) = rpyymnldyv jkyfrxrnxp (zvzregswij, 7.42)
-
24 Aug 2012
Phase 3
174
tqintgaepx(iquekmacpz) = ocjdaenboz ygcszjksbk (ethrswpmvd, 0.73)
-
04 Jul 2012
Phase 3
502
Amlodipine+Telmisartan
(T80/A5)
dawhswsxxv = aybyduujgl svcarviumk (npkdjjfica, lwzcbgofzq - mqqhsnhktx)
-
04 Jul 2012
Amlodipine+Telmisartan
(T80/A10)
zfjjqtjwyj(ueesitqhts) = nlvzmchnqf gyzlsneywr (wcpjicvbeg, djccffscoq - ptdormvxrm)
Phase 3
858
iqqxxdelya(gatagtfyyl) = vmmpxtdshc blarlmfluv (jdmojtmwtm, 0.69)
-
04 Jan 2011
(Telmisartan 80 mg)
iqqxxdelya(gatagtfyyl) = gjanodnkcp blarlmfluv (jdmojtmwtm, 0.96)
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Approval

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Regulation

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