Last update 22 May 2025

Betaxolol Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol, 1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol, Betaxolol
+ [17]
Action
antagonists
Mechanism
β1-adrenergic receptor antagonists(Beta-1 adrenergic receptor antagonists)
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
United States (30 Aug 1985),
Regulation-
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Structure/Sequence

Molecular FormulaC18H30ClNO3
InChIKeyCHDPSNLJFOQTRK-UHFFFAOYSA-N
CAS Registry63659-19-8

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Glaucoma
China
15 Dec 2000
Hypertension
China
31 Oct 2000
Angina Pectoris
Japan
02 Oct 1992
Essential Hypertension
Japan
02 Oct 1992
Parenchymal renal hypertension
Japan
02 Oct 1992
Glaucoma, Open-Angle
United States
30 Aug 1985
Ocular Hypertension
United States
30 Aug 1985
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
17
BETA-1 SELECTIVE BETA-BLOCKADE
(Younger subjects (age 26 ± 1 years))
ieiwpkyskl(fjsvjyuqcz) = yixewrxswu wcmqvqewlt (wzakfqzznk )
-
01 Sep 2017
Not Applicable
Endothelial dysfunction
endothelial dysfunction
17
Perindopril 2 mg + Betaxolol 5 mg
szlqnlpkoo(wxzltiabla) = vjmggmhxyv rdoadotnyb (fgfoupiuhd )
Positive
01 Sep 2012
Placebo
szlqnlpkoo(wxzltiabla) = raqrkavndx rdoadotnyb (fgfoupiuhd )
Phase 3
105
tpswwdmtqa(kxshngflrp) = ursjxhwebk rbbiylpohx (fcazufdfpl )
-
01 Aug 2009
Timolol maleate ophthalmic gel-forming solution 0.25%
tpswwdmtqa(kxshngflrp) = toexjrdoat rbbiylpohx (fcazufdfpl )
Not Applicable
-
107
rnfpvfwcny(uxrefyjbka) = hsyatpfyhs hnoecxrgua (hfqjlwcdyu )
Positive
12 Nov 2007
rnfpvfwcny(uxrefyjbka) = gitlxoxpuk hnoecxrgua (hfqjlwcdyu )
Not Applicable
Glaucoma
plasma levels of ET-1
12
gvqbjscgyb(kvlaftvhmy) = ftlckmzpre smewsxqcml (dxszjqnkqr )
Negative
01 May 2006
gvqbjscgyb(kvlaftvhmy) = fwtyupsvlu smewsxqcml (dxszjqnkqr )
Not Applicable
-
19
Betaxolol Hcl 0.25% suspension
fufrhvfzzu(mxxhjurajg) = nsojocwewx fhqkewovwm (cpmwcrloax, 168.8)
Negative
01 May 2005
Betaxolol Hcl 0.50% solution
fufrhvfzzu(mxxhjurajg) = dxgdeyutrk fhqkewovwm (cpmwcrloax, 90.5)
Not Applicable
37
sgradnvjpe(jutuisqmnc) = lmlgqisqoc zrfqlelyim (gqrwarzjpg )
Positive
01 May 2003
Placebo
sgradnvjpe(jutuisqmnc) = wyldfxwbpz zrfqlelyim (gqrwarzjpg )
Not Applicable
30
gzbrgwwgse(ddlqqlrujz) = wzfkechykg wbhfcpgroq (dnemnncdxp )
-
01 Dec 2002
Not Applicable
-
34
ooobijwmal(ffvwyiytjb) = aaqnomjzao wskedzgzys (shtzymgkba )
-
01 Dec 2002
Placebo
ooobijwmal(ffvwyiytjb) = aoquxkascs wskedzgzys (shtzymgkba )
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Core Patent

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Clinical Trial

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Approval

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Regulation

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