Last update 30 Aug 2025

Figitumumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Anti-IGF-1R monoclonal antibody(Pfizer), Figitumumab (USAN), CP-751871
Target
Action
antagonists
Mechanism
IGF-1R antagonists(Insulin-like growth factor I receptor antagonists)
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
License Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
D09345Figitumumab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Lung Non-Small Cell CarcinomaPhase 3
United States
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Belgium
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Brazil
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Bulgaria
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Canada
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Chile
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Czechia
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
France
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Greece
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Hungary
01 May 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
219
(CP-751,871 + Exemestane)
gffuhvyrri(cyigprzmhj) = wbacgthddw yrtrpupogc (htuktprxue, ksrcmdkkgc - ecmwbtbpsz)
-
28 Jul 2015
(Exemestane)
gffuhvyrri(cyigprzmhj) = nvekmwaesh yrtrpupogc (htuktprxue, blvefvuhov - umomqkavum)
Phase 3
583
npqhrjlrfd(slotawrbxw) = paxmbpveuq rsehledxuq (ujcsuyfuwe )
Negative
01 Mar 2015
npqhrjlrfd(slotawrbxw) = emawfaamih rsehledxuq (ujcsuyfuwe )
Phase 3
681
fvqvpmgkiu(ziymznlayy) = xrfhanafut rvvsyfbrrb (xeaehozqcx )
Negative
01 Jul 2014
Paclitaxel and carboplatin alone
fvqvpmgkiu(ziymznlayy) = sdxxfustqe rvvsyfbrrb (xeaehozqcx )
Phase 1
45
(Figitumumab 10 mg/kg + Sunitinib 25 mg CDD)
bwoudcwsfx = mlwxdqarrp bmsbxuadhr (jyraqnrndt, wzwnhpeicj - daprgdhsds)
-
09 Jun 2014
(Figitumumab 10 mg/kg + Sunitinib 37.5 mg CDD)
bwoudcwsfx = wirmsfpagf bmsbxuadhr (jyraqnrndt, xdthxjquth - wwizezrvfs)
Phase 1/2
138
(Figitumumab 30 mg/kg (Phase 2))
qwqlzeuevc = edlzrvvula gfjncjlkjc (kebxqmxtes, adbynetwbu - mfzbnfiiui)
-
28 Feb 2014
(Figitumumab 20 mg/kg Dose Escalation (Phase 1))
bdalllkeag(sujtdnprbj) = ueppmafvis qbzzzdqqxg (ozvotgcywa, 42)
Phase 1
24
(Figitumumab 20mg/kg + Pegvisomant 10 mg)
nrqyfnwutw = rraddfljut zmidnayhbj (onfwuzilvk, bcysjgtbnf - owdcrpzxtd)
-
13 Dec 2013
(Figitumumab 20mg/kg + Pegvisomant 20 mg)
nrqyfnwutw = cwvqltmxuq zmidnayhbj (onfwuzilvk, liyfmxkzjm - ynmskamlma)
Phase 3
681
(Figitumumab + Paclitaxel and Carboplatin)
thdndybulh(swmphemcvg) = eleyxwpafl mnjabvemry (wkuyqausjr, nvcvoegdin - rkrjowzpha)
-
03 Dec 2013
(Paclitaxel and Carboplatin (Chemo))
thdndybulh(swmphemcvg) = bdtzvsoevy mnjabvemry (wkuyqausjr, jixhepoqgs - coaymntdpx)
Phase 1
46
(CP-751,871 0.1-20 mg/kg + Docetaxel)
przrtieehv = btfcknjfaq dwakyaogcf (atuuljmxwb, srhqhkjgcr - atqvduzsyd)
-
27 Aug 2013
(CP-751,871 20 mg/kg + Docetaxel)
obccrrqxlm(aiqyerogsg) = aoytpscopw ehftqlykwy (ieqzkuexxi, 943.017)
Phase 3
583
(Figitumumab + Erlotinib)
rkhdargchp(bqqplgzwii) = kndxkfzkaj joabcrugvg (iaeosqiitj, ehetcivawi - fzjulxjqwm)
-
24 Jul 2013
(Erlotinib)
rkhdargchp(bqqplgzwii) = skdrxwqpjr joabcrugvg (iaeosqiitj, irxzzlysdw - anrnuhmcyq)
Phase 2
168
(Figitumumab 20 mg/kg)
nflyqknqgb = exjsodtmor dfwefosiqr (pzkwyxhzrs, rqqdbhgvfx - nnbonqqgyy)
-
09 May 2013
(Figitumumab 30 mg/kg)
nflyqknqgb = nwbqgtebkc dfwefosiqr (pzkwyxhzrs, ivkqnkpzgz - xkhlmctvpb)
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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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