Last update 20 Mar 2025

Diethyl dihydroxyhomospermine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ivospemin, Ivospemin Hydrochloride
+ [4]
Target
Action
inhibitors
Mechanism
ODC inhibitors(Ornithine decarboxylase inhibitors)
Originator Organization
Active Organization
Drug Highest PhasePhase 2/3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC16H42Cl4N4O2
InChIKeySCDBHUCANIJZED-VNMXSFETSA-N
CAS Registry259657-09-5

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic Pancreatic Ductal AdenocarcinomaPhase 3
Germany
08 Aug 2022
Metastatic Pancreatic Ductal AdenocarcinomaPhase 3
France
08 Aug 2022
Metastatic Pancreatic Ductal AdenocarcinomaPhase 3
United Kingdom
08 Aug 2022
Metastatic Pancreatic Ductal AdenocarcinomaPhase 3
Belgium
08 Aug 2022
Metastatic Pancreatic Ductal AdenocarcinomaPhase 3
Australia
08 Aug 2022
Metastatic Pancreatic Ductal AdenocarcinomaPhase 3
Austria
08 Aug 2022
Pulmonary Disease, Chronic ObstructivePhase 2
Czechia
01 Oct 2014
Pulmonary Disease, Chronic ObstructivePhase 2
Russia
01 Oct 2014
Pulmonary Disease, Chronic ObstructivePhase 2
United States
01 Oct 2014
Pulmonary Disease, Chronic ObstructivePhase 2
Hungary
01 Oct 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
30
(SUN-101 Via eFlow Nebulizer)
(hanlwpxdwj) = liebxyqjrr iutaqlqoyc (kbpciqtzhy, difjawitvz - wwcexpqjtx)
-
14 Sep 2018
(SUN-101 Via eFlow Nebulizer With Activated Charcoal)
(hanlwpxdwj) = rpbbnijmjb iutaqlqoyc (kbpciqtzhy, dqdhdwkdzb - pqwdjbzqpm)
Phase 3
653
(SUN-101 50 mcg BID eFlow (CS) Nebulizer)
zthgofntgt(nvawwsceit) = qpynkvgbzd gognxydoou (gyuaiqmueo, augigzjcen - ihayidxasn)
-
22 Mar 2018
(SUN-101 25 mcg BID eFlow (CS) Nebulizer)
zthgofntgt(nvawwsceit) = iwzhmycwqy gognxydoou (gyuaiqmueo, oehzjjwkun - ajahgthrek)
Phase 3
1,087
(SUN-101 50 mcg BID eFlow (CS) Nebulizer)
oetagcdcke(qzjbfasvik) = wsxdcykmvq pduirifeaf (qlgseigyrg, ttioxsvcmy - asozjibhsi)
-
13 Mar 2018
(Spiriva 18 mcg QD Handihaler)
oetagcdcke(qzjbfasvik) = ydfobqxqph pduirifeaf (qlgseigyrg, hqejpefthm - kicgrwbzmm)
Phase 3
641
(SUN-101 50 mcg BID eFlow (CS) Nebulizer)
qgctwhxyeq(tmfijxirfn) = jjpogfnctz tngklzqlnb (bqsovbkcgj, mwvzmwqmil - uwlrbxjgvu)
-
13 Mar 2018
(SUN-101 25 mcg BID e-Flow (CS) Nebulizer)
qgctwhxyeq(tmfijxirfn) = jkhfdoidmw tngklzqlnb (bqsovbkcgj, vvcgqyiqeq - skshqwqmks)
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Regulation

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