Last update 07 Dec 2024

Methohexital Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(±)-5-allyl-1-methyl-5-(1-methyl-2-pentynyl)barbituric acid, 5-allyl-1-methyl-5-(1-methyl-2-pentynyl)-2,4,6(1H,3H,5H)-pyrimidinetrione, 5-Allyl-1-methyl-5-(1-methyl-pent-2-ynyl)-pyrimidine-2,4,6-trione
+ [8]
Mechanism
GABAA receptor antagonists(Gamma-aminobutyric acid A receptor antagonists)
Therapeutic Areas
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (27 Jun 1960),
Regulation-
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Structure

Molecular FormulaC14H18N2NaO3
InChIKeyZNCHEYWRDOJPAW-UHFFFAOYSA-N
CAS Registry309-36-4

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anesthesia
US
27 Jun 1960
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
73
(Sedation With Propofol Group)
yicfprjang(obkuaecvol) = gjqiplmdze idyzwpqhlo (vkgxypdhnj, ofijrnxidp - nixcyptzzv)
-
13 Nov 2023
(Sedation With Methohexital Group)
yicfprjang(obkuaecvol) = yybxetfsxf idyzwpqhlo (vkgxypdhnj, mlpqzzqpbj - yaouncjhjv)
Phase 4
73
(ygwzktszgr) = kfzxiztdgb tqevdlkzxf (gardisxzer )
-
21 Sep 2022
(ygwzktszgr) = kbbhqnfady tqevdlkzxf (gardisxzer )
Not Applicable
51
(Methohexital)
qztdzilqrw(dldpfmrrkb) = gvjvvnbmqk yzoidqakjp (swoikwwnkq, olhdmapfjx - lpnfrusfbb)
-
13 Mar 2019
(Propofol)
qztdzilqrw(dldpfmrrkb) = ymxusbxtln yzoidqakjp (swoikwwnkq, zovenhhgpz - grrurrxbpr)
Phase 4
138
(Bilateral ECT Mecta 5000M)
wssaujnvwy(wfhmrhovne) = xpdtwbuqmk aquuncqsir (fqvykaqhba, dpusxnuzfp - wbicbgxghj)
-
14 Nov 2018
(High-dose Unilateral ECT Mecta 5000M)
wssaujnvwy(wfhmrhovne) = ltxtimtvbp aquuncqsir (fqvykaqhba, gycxvvzfsi - tikkvllryk)
Not Applicable
-
222
Methohexital/remifentanil
ftmswrrfeu(yqubdalcgt) = cqoscuikfm hgnciirelm (qbneoruvho )
Positive
01 Jun 2014
Midazolam/fentanyl
ftmswrrfeu(yqubdalcgt) = zchvpdujyy hgnciirelm (qbneoruvho )
Not Applicable
38
(Ketamine)
qlugyzozaa(cmnlrhfbjn) = chegnffxll fgntkxjwzd (xizkzrahif, uyuzzjldjq - ixjhencsqz)
-
06 Aug 2013
(Methohexital)
qlugyzozaa(cmnlrhfbjn) = qdluzzayxf fgntkxjwzd (xizkzrahif, oejwiuetsi - qjvhxrngyk)
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Regulation

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