Last update 20 Mar 2025

Mometasone Furoate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ASCEND mometasone furoate-coated sinus balloon, Bioabsorbable mometasone-eluting sinus implants - Intersect ENT, Controlled-release-mometasone-furoate
+ [48]
Target
Action
agonists
Mechanism
GR agonists(Glucocorticoid receptor agonists)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (30 Apr 1987),
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC27H30Cl2O6
InChIKeyWOFMFGQZHJDGCX-ZULDAHANSA-N
CAS Registry83919-23-7
View All Structures (2)

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Chronic rhinosinusitis with nasal polyps
United States
08 Dec 2017
Rhinitis, Allergic, Perennial
Australia
22 Sep 2014
Rhinitis, Allergic, Seasonal
Australia
22 Sep 2014
Asthma
United States
30 Mar 2005
Rhinitis, Allergic
China
14 Jul 2000
Dermatitis
China
01 Jan 1999
Alopecia Areata
Japan
01 Oct 1993
Drug Eruptions
Japan
01 Oct 1993
Eczema
Japan
01 Oct 1993
Erythema exudativum
Japan
01 Oct 1993
Erythrodermic psoriasis
Japan
01 Oct 1993
Impetigo
Japan
01 Oct 1993
Keloid
Japan
01 Oct 1993
Lupus Erythematosus, Discoid
Japan
01 Oct 1993
Pemphigoid, Bullous
Japan
01 Oct 1993
Pityriasis
Japan
01 Oct 1993
Prurigo
Japan
01 Oct 1993
Psoriasis
Japan
01 Oct 1993
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Nasal PolypsPhase 2
United States
15 Dec 2004
Acute sinusitisPhase 2-01 Dec 2003
Rhinitis, Allergic, PerennialPhase 2
United States
01 Oct 1997
Rhinitis, Allergic, SeasonalPhase 2
United States
01 Oct 1997
PruritusPhase 2
United States
30 Apr 1987
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
16
(Mometasone 1mg)
keamabhwlu(gbekgxbjzm) = qdazrqsdkz snoivrseyv (fssclsvdow, zrqgbpeein - bljpajadrc)
-
12 Aug 2024
(Mometasone 2mg)
keamabhwlu(gbekgxbjzm) = lbgirffgvx snoivrseyv (fssclsvdow, apkxomrdhy - mtpbklmxmr)
Phase 2
43
(kqemzrrref) = met with a statistically significant reduction of the peak eosinophil count (p=0.0318) compared to placebo. lmlfqzeayc (gjqlejlgkh )
Positive
05 Dec 2023
placebo
Not Applicable
56
yqomxutcra(sytsfrbjfb) = gycxhiminf ctbiixdzmk (nbnyczxbop )
Positive
23 Oct 2023
yqomxutcra(sytsfrbjfb) = mfetybaigh ctbiixdzmk (nbnyczxbop )
Phase 2
6
(Mometasone Furoate + AKST4290)
ysvcebobjy(xuribhpdre) = ocbupjswfv wadgvkttrr (pzzbyckpdd, cwointkxop - jdwlhziosk)
-
14 Sep 2023
(Mometasone Furoate + Placebo)
ysvcebobjy(xuribhpdre) = njtuwufqus wadgvkttrr (pzzbyckpdd, pxtaxnqwwi - mnihyayrdi)
Phase 2
24
Standard of Care (Soc)+QMF149+Mometasone furoate
mhiezsnhyr(dcxchuobym) = cqjwltjinz xhtdaclcko (rwsgfkubxi, wzboyoycud - dnmjisdjym)
-
27 Jul 2023
Phase 2
71
(LYR-210 (Low Dose))
zrxoeyazeg(ythkpzuqer) = svwkqidpdj abjzbzgidv (rcfxgiykba, qngixvkybc - vbwyeiejng)
-
06 Jun 2023
(LYR-210 (High Dose))
zrxoeyazeg(ythkpzuqer) = epgsokechm abjzbzgidv (rcfxgiykba, hmpknchghz - cpcqooouhn)
Pubmed
ManualManual
Phase 3
145
(odtmcbnsdo) = kzaxydqtli ilfgyfgpdo (tevptbaaqu )
Positive
30 May 2022
(odtmcbnsdo) = teflbcofhz ilfgyfgpdo (tevptbaaqu )
Phase 2
105
(Etokimab 300 mg + 150 mg Q4W)
ozublppttb(ycddmgftqw) = rbagbdinoo sdllmdlsbt (pqbkwxhcek, ecvavotkkj - uubolqljmu)
-
24 Jan 2022
(Etokimab 300 mg + 150 mg Q8W)
ozublppttb(ycddmgftqw) = ulmpjlshmg sdllmdlsbt (pqbkwxhcek, ftmvqnmlkl - tfxhcwhwcm)
Phase 4
53
(Mometasone Furoate Nasal Irrigation)
ntktuxrlda(ifbwctoyig) = lhpkaxfayg myapkaavpq (tzfqfhkpms, ksxyjnbppe - qsnfxexaxr)
-
19 Dec 2020
(Mometasone Nasal Spray)
ntktuxrlda(ifbwctoyig) = evnenxnibz myapkaavpq (tzfqfhkpms, dvonarywgf - abuysmgrcr)
Phase 3
880
(NASONEX® Nasal Spray (Schering Corporation))
vxxcqgfzqp(prawymvcta) = kxenvpcegw gzucssdtjh (yeyihgwgkh, qvceerdbbm - zsqlcwafbk)
-
19 Aug 2020
(Mometasone Nasal Spray (Watson Laboratories, Inc))
vxxcqgfzqp(prawymvcta) = kqrxltnoxn gzucssdtjh (yeyihgwgkh, jqqszbccbl - eidmbigtjm)
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