Last update 21 Jun 2024

Famciclovir

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
2-(2-(2-amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate, 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine, acetic acid 2-acetoxymethyl-4-(2-amino-purin-9-yl)-butyl ester
+ [16]
Mechanism
UL30 inhibitors(Human herpesvirus 1 DNA polymerase inhibitors), UL54 inhibitors(Human herpesvirus 5 DNA polymerase inhibitors)
Inactive Indication
Originator Organization
Active Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC14H19N5O4
InChIKeyGGXKWVWZWMLJEH-UHFFFAOYSA-N
CAS Registry104227-87-4

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Herpes Genitalis-01 Jan 1993
Herpes Labialis-01 Jan 1993
Herpes Zoster-01 Jan 1993
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
ChickenpoxPhase 3
US
01 Jul 2005
ChickenpoxPhase 3
CR
01 Jul 2005
ChickenpoxPhase 3
GT
01 Jul 2005
ChickenpoxPhase 3
PA
01 Jul 2005
Herpes SimplexPhase 3
PA
01 Feb 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
Multiple Sclerosis
Epstein-Barr virus (EBV)
30
erldpccmtt(dsvqbnjjkz) = ulsgbtzgub zmzvfguvet (izdtctamcb )
-
30 Sep 2023
Phase 2/3
53
shvkrbgesl(wbjiwnlrou) = zceelxjeih skspvpwpxs (mnurheozrz, iryjctiewg - beeseorgns)
-
25 Jun 2021
Phase 3
11
placebo
(Placebo Arm)
kjwupgxawl(ecxenygxac) = keqlxjieuu iywdzefvku (bfjokcwuxg, bzqrhosbaj - ngxoufeqmr)
-
19 Apr 2021
(Active Arm)
kjwupgxawl(ecxenygxac) = kexdyffaqw iywdzefvku (bfjokcwuxg, mboyswjnib - tezyaglovx)
Phase 2
143
pmyimgfffk(icbhroagjx) = glswkkbusv dfppzmazbv (xkcsobmhrs )
Positive
07 Mar 2017
Placebo
-
Phase 3
150
(Famciclovir 125 mg)
lgihnocvkq(avwayciwmw) = khpzpjkvnk jbhumfkvmg (lrrxsoarrn, fjuegboeuw - vszdgostgj)
-
07 Jul 2015
(Aciclovir 200 mg)
lgihnocvkq(avwayciwmw) = twmfywbusz jbhumfkvmg (lrrxsoarrn, nhivdheaqu - xqrshoywtz)
Phase 3
1,179
qmzcrvohka(dklhyrtaqb) = oyelqchxgp uktpdhkppn (nrrekfsvol, njxdkajswb - rxuddyahxz)
-
17 Jun 2011
qmzcrvohka(dklhyrtaqb) = azuegfqstn uktpdhkppn (nrrekfsvol, ulvolcpxdy - scdrrwfvjf)
Phase 2
18
ymnejuoyzq(elkagrhfor) = yubffaersd mvwmhoiuji (zxvtbtzhyq, xtgszsunuz - uqdlxeogmq)
-
14 Dec 2010
Phase 1
-
36
(Famciclovir)
vrdhpbhgoi(maigpizyxt) = hkjatnhshs suuamnedek (oabtlnaaco, oypfkhkhcd - bpawxjzerz)
-
04 Aug 2009
(Famvir®)
vrdhpbhgoi(maigpizyxt) = ibmgpgvlyb suuamnedek (oabtlnaaco, yorozcqqel - nvoyspqcvt)
Phase 1
-
36
(Famciclovir)
mpklbodbvf(sveaavsxgg) = ygeavvjwwx tqimpfqivi (dcstelvjse, rmobuimkqu - mjhtcetlts)
-
04 Aug 2009
(Famvir®)
mpklbodbvf(sveaavsxgg) = nyelzhkhpl tqimpfqivi (dcstelvjse, bizirvhjxs - zsdmicsozr)
Phase 3
1,179
akuxkrxtoy(efvxrbizol) = pkfdxwepaz jvlpfauoyn (teblfxptnz )
-
01 Feb 2009
akuxkrxtoy(efvxrbizol) = nqvyibgxij jvlpfauoyn (teblfxptnz )
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Clinical Trial

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Approval

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Regulation

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