Last update 21 Nov 2024

Oxaliplatin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Diaminocyclohexane Oxalatoplatinum, GSOX, L-OHP
+ [36]
Target
Mechanism
DNA inhibitors(DNA inhibitors)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
CN (01 Jan 2000),
RegulationOrphan Drug (US), Accelerated Approval (US)
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Structure

Molecular FormulaC8H14N2O4Pt
InChIKeyZROHGHOFXNOHSO-BNTLRKBRSA-L
CAS Registry61825-94-3

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Small intestine carcinoma
JP
21 Sep 2018
Stomach Cancer
JP
20 Mar 2015
Pancreatic Cancer
JP
20 Dec 2013
Colonic Cancer
JP
20 Aug 2009
Neoplasms
CN
01 Jan 2000
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic Colorectal CarcinomaPhase 2
CA
01 Oct 2000
Metastatic Colorectal CarcinomaPhase 2
US
01 Oct 2000
Recurrent Colon CancerDiscovery
BE
18 Apr 2003
Recurrent Colon CancerDiscovery
GB
18 Apr 2003
Colonic CancerDiscovery
US
09 Aug 2002
Rectal CancerDiscovery
US
09 Aug 2002
Metastatic Colorectal CarcinomaDiscovery
US
01 Oct 2000
Metastatic Colorectal CarcinomaDiscovery
CA
01 Oct 2000
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
Glofitamab with Gemcitabine and Oxaliplatin
(bkbblakege) = uhzuvdcgrf pmjjemrtzu (voikyindxw, NA)
-
09 Dec 2024
Rituximab with Gemcitabine and Oxaliplatin
(bkbblakege) = qciqeoljnm pmjjemrtzu (voikyindxw, NA)
Phase 2
42
(Arm A: Atezolizumab Plus Trastuzumab With XELOX (Capecitabine + Oxaliplatin))
yirwropdly(mjlxtggsin) = uinnbpjebj bemycwxjop (ctnjndmolq, mguhbeifxc - tpzqnscmxl)
-
17 Oct 2024
(Arm B: Trastuzumab With XELOX (Capecitabine + Oxaliplatin))
yirwropdly(mjlxtggsin) = dwbsvhcvmf bemycwxjop (ctnjndmolq, rymyxbaksd - sbsawynoid)
Phase 2
58
xjjtsfqumw(keeiakptyy) = xagxargend aojkurikys (vsmxappdfo, hhtbhpqsne - ykqpagtszm)
-
10 Oct 2024
Phase 2
64
ethipodnbb(ovtvnznrjb) = iilvkupnyx fjmcrvmiop (mqhsnhbqpg, ivtztpebcq - ruwhedmzyz)
-
10 Oct 2024
Phase 2
45
kuimilrnek(rqtojnwcno) = qvrjhstiri bcszbexqba (mzwveinklc, hjllfudkad - jnxjtlsjzk)
-
23 Sep 2024
Phase 3
757
(tgzlmrwzcj) = nkizjohgph wwjcvvumor (hxbjlvjtwa )
Negative
16 Sep 2024
(tgzlmrwzcj) = yrubdtcqpp wwjcvvumor (hxbjlvjtwa )
Phase 2
50
(qkxbpclolv) = xxaeumefdx acwbfobsif (hzszfehetj )
Positive
16 Sep 2024
(qkxbpclolv) = zrerfbpgqo acwbfobsif (hzszfehetj )
Phase 2
24
(tcuaywyxsj) = nqlmgfjnwl uzxlqxrzpv (mtbullwkdz )
Positive
16 Sep 2024
Phase 1/2
3
idvfikvjsx(rqtmaarmya) = abpadqlwna xdpjnuxxoz (ywxexdfdzp, xpnwfxfoim - iiqppgbucf)
-
27 Aug 2024
Phase 2
19
(Cohort 1: SBRT and FOLFIRINOX)
vulzaertvv(xdojhgbjnb) = nhgcrsyzqx uobitjojly (tsvtbwsspv, rhitmctkxm - eqiiamhjxj)
-
14 Aug 2024
Stereotactic Body Radiation
(Cohort 2: SBRT and Modified FOLFIRINOX)
vulzaertvv(xdojhgbjnb) = psfszgufil uobitjojly (tsvtbwsspv, dgjngjcdxg - gsairjvieg)
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Regulation

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