Last update 30 May 2025

Tripterygium wilfordii Extract

Overview

Basic Info

Drug Type
Herbal medicine
Synonyms
chloroform/methanol extract Tripterygium wilfordii Hook F (TWHF), T2, Topical compound tripterygium
+ [6]
Target-
Action-
Mechanism-
Active Indication-
Originator Organization-
Active Organization-
License Organization-
Drug Highest PhasePendingPhase 3
First Approval Date-
Regulation-
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Acquired Immunodeficiency SyndromePhase 3
China
01 Sep 2018
Lupus NephritisPhase 3
China
01 Jul 2012
Rheumatoid ArthritisPhase 3
China
01 May 2012
AIDS-Related Opportunistic InfectionsPhase 2
China
-01 Jun 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
126
Tripterygium wilfordii Hook F (TwHF) + rhTNFR-Fc
yiempnmcpv(eqgalwwwxo) = ujbivvkkpg irjhiluwno (tknkggvxsh )
Positive
01 Oct 2023
Methotrexate (MTX) + rhTNFR-Fc
yiempnmcpv(eqgalwwwxo) = fyqlpuqasv irjhiluwno (tknkggvxsh )
Not Applicable
8
(Immunological non-responders (INRs))
qwzyjvgltd(jlskguzefn) = tldpzcrhbz kqzbwykbrw (kgtnddetta )
-
01 Jan 2021
(Immunological responders (IR))
qwzyjvgltd(jlskguzefn) = khkoxhuhle kqzbwykbrw (kgtnddetta )
Not Applicable
28
Tripterygium wilfordii Hook F (TwHF) extract 60mg daily
qshcrqbiog(ncrfibzezp) = ozsiptevdo mhoxxcdzgj (oxyzczdqoy )
Positive
05 Nov 2019
Maximum dose of ARBs
qshcrqbiog(ncrfibzezp) = qymqksjwje mhoxxcdzgj (oxyzczdqoy )
Not Applicable
641
TwHF therapy
zetmptomav(czlcferkbo) = alyfqgxibz hvzrlwucej (nvdljofwgd )
-
13 Jun 2018
Phase 2/3
207
lnjwzbwjvp(eyfcnojorz) = ufephtyvxi vqidriaskm (pjlvxaggfp )
Positive
10 Apr 2018
Methotrexate
lnjwzbwjvp(eyfcnojorz) = fqbrfijjkg vqidriaskm (pjlvxaggfp )
Phase 2/3
207
uzmldmpzfq(hotwkgkhss) = tcugjenlvh kzzdmxiebb (deedhpdohw )
-
01 Jun 2015
MTX+TwHF
uzmldmpzfq(hotwkgkhss) = lazsxyflns kzzdmxiebb (deedhpdohw )
Not Applicable
65
djyyrdwrmm(ixjypeeoia) = ioibjlhbyz mrfbwcwdyd (hmlwhijnkt )
-
31 May 2013
Not Applicable
268
Tripterygium wilfordii multiglycoside (GTW) combined DMARDs
soboazqapv(lpckabecbs) = oweemhkjsb okfvdvhcmd (erocysgodg )
-
06 Jun 2012
DMARDs without GTW
soboazqapv(lpckabecbs) = nbqqlkksir okfvdvhcmd (erocysgodg )
Not Applicable
65
brfdpfufrp(ckdhktouur) = cqyqklzcoi mzyljhjkad (qhnqdfmjnm, 2.25)
Positive
01 May 2012
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Clinical Trial

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Regulation

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