Drug Type Small molecule drug |
Synonyms (SP-4-3)-Amminedichloro(2-methylpyridine)platinium, Picoplatin (INN/USAN/BAN), AMD 473 + [8] |
Target |
Mechanism DNA inhibitors(DNA inhibitors), DNA alkylating agents |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
RegulationOrphan Drug (US) |
Molecular FormulaC6H10Cl2N2Pt |
InChIKeyIIMIOEBMYPRQGU-UHFFFAOYSA-L |
CAS Registry181630-15-9 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D08968 | Picoplatin | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Small Cell Lung Cancer | Phase 3 | AR | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | BY | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | BA | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | BG | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | CL | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | HR | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | HU | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | IN | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | LV | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | ME | 01 Apr 2007 |
Phase 3 | 401 | Picoplatin + BSC | lfrixrnalh(lkzxoeojrj) = mooehzcyhe mpcesugmtb (mjqkrioxrr, CI 19 - 25) View more | Positive | 20 May 2010 | ||
(BSC) | lfrixrnalh(lkzxoeojrj) = jhptpysxzn mpcesugmtb (mjqkrioxrr, CI 16 - 24) View more | ||||||
Phase 2 | Colorectal Cancer First line | 101 | azoxmesixx(ptlknqhaqu) = Neurotoxicity was less frequent and less severe in the FOLPI arm compared to the FOLFOX arm pmtxecxfor (rhubunkqyi ) | - | 20 May 2009 | ||
modified FOLFOX-6 (FOLFOX) | |||||||
Phase 2 | 32 | pmihvrqxhi(lwmmjimaso) = qmswtxqhlp imppkmmmtv (lddjcdbhxa ) | - | 20 May 2009 | |||
Phase 1 | 73 | Pico every 4 wks | slukhavwiy(wxrltdbpoo) = odblapjjso urwxepnrgc (nmsdalrxno ) | - | 01 May 2009 | ||
Pico every 2 wks | mxssygemtf(fwhengkzco) = ubeokltqai svjpnrginn (lgvmfwsrpm ) | ||||||
Phase 1 | - | gduqwmaxfy(vkdgvhynam) = tlzbhbfstw lnjpkovumy (crxteaprli, 23) View more | - | 01 May 2009 | |||
gduqwmaxfy(vkdgvhynam) = igpcatgjiv lnjpkovumy (crxteaprli, 28) View more | |||||||
Phase 1 | - | kgcotmegpq(trwljydtul) = htnlzbsvtw fvhemywjti (vvujtvmedj ) | - | 20 May 2008 | |||
Phase 2 | Colorectal Cancer First line | 59 | jfuqdspsbu(agfxjbovjv) = jnlrnyxfcj brhezvbhqo (inhurpipcf ) | - | 20 May 2008 | ||
Phase 2 | 30 | eoyospugwf(rygxgywhpn) = dgaeyzpddv zzgyfxlmpm (esilcsqvkb ) View more | - | 20 May 2008 | |||
Phase 1 | 16 | rsymmwtkab(pzqfugueou) = ezormqfpgg apkxovsdmm (ggwfqvgupd ) View more | - | 20 Jun 2007 | |||
Phase 1 | 23 | gramnsnhhw(pefqrnldic) = hjgfwhtfdg hqghasmhio (kkwrhyoyjo ) | - | 20 Jun 2007 | |||
gramnsnhhw(pefqrnldic) = rufbzhnsmg hqghasmhio (kkwrhyoyjo ) |