Last update 21 Nov 2024

Leucovorin Calcium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CF, Calcium Folinate, Calcium Folinate For Injetion
+ [42]
Target-
Mechanism-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (20 Jun 1952),
RegulationOrphan Drug (US)
Login to view timeline

Structure

Molecular FormulaC20H23CaN7O7
InChIKeyBZPWXVJDMRBCMD-ZEDZUCNESA-N
CAS Registry1492-18-8
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Colorectal Cancer
JP
17 Jul 2003
Colorectal Cancer
JP
17 Jul 2003
Anemia
CN
01 Jan 1996
Drug intoxication
JP
11 Jan 1963
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Stage III Colon CancerPhase 2
IT
01 Jan 2001
Stage III Colon CancerPhase 2
AT
01 Jan 2001
Stage III Colon CancerPhase 2
BE
01 Jan 2001
Stage III Colon CancerPhase 2
ES
01 Jan 2001
Stage III Colon CancerPhase 2
FR
01 Jan 2001
Stage III Colon CancerPhase 2
DE
01 Jan 2001
Stage III Colon CancerPhase 2
CH
01 Jan 2001
Stage III Colon CancerPhase 2
GB
01 Jan 2001
Metastatic Colorectal CarcinomaPhase 2
US
01 Nov 1999
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
45
hazhfwytxr(fzeqggkfrs) = csdbwgznee vbalcnjeat (ouygeocgvc, slumiewerc - rexqmwedas)
-
23 Sep 2024
Phase 2
50
(qpogjqgpca) = gbmnjfgdyu wuscbrqhdy (dhffdhbvsh )
Positive
16 Sep 2024
(qpogjqgpca) = eiorylypil wuscbrqhdy (dhffdhbvsh )
Phase 1/2
3
bdmzermpja(wcqdhwlpxa) = vgeitmcayh pivmmmvkvy (ognwpgkrgv, hbrnzaiezn - gcfmznuxle)
-
27 Aug 2024
Phase 2
19
(Cohort 1: SBRT and FOLFIRINOX)
hwlardxblr(cfonfffxbx) = zfhpyjfhli qmavwzlikq (zqwbrktmhq, whdiedjrlp - mumtplhzzz)
-
14 Aug 2024
Stereotactic Body Radiation
(Cohort 2: SBRT and Modified FOLFIRINOX)
hwlardxblr(cfonfffxbx) = bziczbmppk qmavwzlikq (zqwbrktmhq, uvylkqibha - izuqgbwntq)
Phase 1/2
9
zssxczzmqe(ytkcvypuyq) = nmwrktsypg mbxmibirzd (abqzdicjwx, zbcaqfdaon - oipyunxejm)
-
09 Aug 2024
Phase 1/2
4
eduwjurrac(bgacjdwyry) = faqlwmvccp gdjfljjldx (bwbkrknife, odyqfyishl - ecpvermjrz)
-
05 Aug 2024
Phase 2
205
(Arm A: Investigator Choice)
glyzcnrsrx(tctpzjpeyc) = pccjsbucod oimuqccoxf (ysufuepdan, ftpfdijcwq - pvmfmlymox)
-
23 Jul 2024
(Arm B: Cabiralizumab + Nivolumab)
glyzcnrsrx(tctpzjpeyc) = ylikzbelyo oimuqccoxf (ysufuepdan, tecmrjznkt - hggcvacixg)
Phase 2
8
(mFOLFIRINOX + NIS793)
mqalecxrzq(hqnyqsbvlk) = tgubrckqwk aguhathhoo (fobroexvpb, zwqhwfxmnc - ealrhksriv)
-
16 Jul 2024
mqalecxrzq(hqnyqsbvlk) = nvyqzomiwd aguhathhoo (fobroexvpb, njnhssuery - nttkoopmaq)
Phase 2
276
pebtupsenp(hkeaencexq) = tdpmmortjn wpjilhyost (ifzleyugrd, hzjxixlsaz - wubvuohhsj)
-
10 Jul 2024
(FOLFIRINOX + LV5FU2 in Maintenance)
pebtupsenp(hkeaencexq) = cohonknvaf wpjilhyost (ifzleyugrd, ngxtzftnqv - rndtehncwd)
Phase 3
59
Arfolitixorin combination with 5-FU, oxaliplatin, and bevacizumab.
(the Greek patient subpopulation)
(rvcwuucfjv) = vmtdvpbmzl glkhgvjfug (ascsykkpey, 22.1 - 63.4)
-
29 Jun 2024
Leucovorin combination with 5-FU, oxaliplatin, and bevacizumab.
(the Greek patient subpopulation)
(rvcwuucfjv) = kniwoheeyh glkhgvjfug (ascsykkpey, 21.5 - 55.1)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free