Drug Type Small molecule drug |
Synonyms FW-CD, FW-COV, FW-ICI-AC + [24] |
Target |
Mechanism AR-v7 inhibitors(androgen receptor splice variant 7 inhibitors), Mitochondrial oxidative phosphorylation uncouplers |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 2/3 |
First Approval Date- |
Regulation- |
Molecular FormulaC13H10Cl2N2O5 |
InChIKeyZBXRPLQCPHTHLM-UHFFFAOYSA-N |
CAS Registry73360-56-2 |
Start Date21 Nov 2022 |
Sponsor / Collaborator |
Start Date11 May 2022 |
Sponsor / Collaborator |
Start Date31 Mar 2022 |
Sponsor / Collaborator |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00436 | Niclosamide |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Ascariasis | US | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
COVID-19 | Phase 3 | US | 07 Oct 2020 | |
Diabetic Nephropathies | Phase 3 | EG | 01 Feb 2020 | |
Gastrointestinal infection | Phase 2 | US | 30 Apr 2021 | |
Gastrointestinal infection | Phase 2 | IN | 30 Apr 2021 | |
Gastrointestinal infection | Phase 2 | UA | 30 Apr 2021 | |
Proctocolitis | Phase 2 | IT | 15 May 2018 | |
Ulcerative proctitis | Phase 2 | IT | 15 May 2018 | |
Crohn Disease | Phase 1 | - | - | |
Diarrhea | Preclinical | US | 15 Jul 2022 |
Study | Phase | Population | Analyzed Enrollment | Group | Results | Evaluation | Publication Date |
---|
NCT04317430 (Literature) Manual | Phase 3 | 60 | ipgxhfowfg(lapqlkjydr) = tpzyfsjsmf xhdtmldsek (tuuhxftvxn, -30to-18.3) View more | Positive | 16 Feb 2023 | ||
ipgxhfowfg(lapqlkjydr) = vtiinrlhld xhdtmldsek (tuuhxftvxn, 4to18.2) View more | |||||||
NCT04399356 (Pubmed) Manual | Phase 2 | 73 | iwjivayjwg(ysfeudbudp) = jnfvhjyouv xyyvczzalr (huxvdnndow, 50.74 - 81.81) View more | Negative | 01 Feb 2022 | ||
Placebo | iwjivayjwg(ysfeudbudp) = jzzhmiircf xyyvczzalr (huxvdnndow, 40.27 - 72.73) View more | ||||||
Phase 2 | 6 | gnmsktlfbx(afchjhisdz) = two with partial PSA response (≥50% decrease) epnonntdxl (rvkjjpzmjv ) View more | Positive | 01 Jun 2018 | |||
Not Applicable | - | qgtdqqqidb(okyjvhjovx) = I/R-induced fatty acid deposition in tubular epithelium was almost diminished in niclosamide-treated mice nccpuetszt (zztoxbvbub ) View more | Positive | 15 Nov 2016 |