Last update 08 May 2025

Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Disoproxil Fumarate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
EVG/COBI/FTC/TDF, Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil, Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil Fumarate
+ [4]
Action
inhibitors
Mechanism
CYP3A inhibitors(Cytochrome P450 3A inhibitors), HIV-1 integrase inhibitors(HIV integrase inhibitors), RT inhibitors(Viral reverse transcriptase inhibitors)
Active Indication
Originator Organization
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (27 Aug 2012),
RegulationOrphan Drug (Japan), Fast Track (United States)
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Structure/Sequence

Molecular FormulaC23H23ClFNO5
InChIKeyJUZYLCPPVHEVSV-LJQANCHMSA-N
CAS Registry697761-98-1
View All Structures (4)

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
HIV Infections
United States
27 Aug 2012
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acquired Immunodeficiency SyndromePreclinical
Canada
01 Nov 2011
Acquired Immunodeficiency SyndromePreclinical
Germany
01 Nov 2011
Acquired Immunodeficiency SyndromePreclinical
Italy
01 Nov 2011
Acquired Immunodeficiency SyndromePreclinical
France
01 Nov 2011
Acquired Immunodeficiency SyndromePreclinical
Belgium
01 Nov 2011
Acquired Immunodeficiency SyndromePreclinical
Puerto Rico
01 Nov 2011
Acquired Immunodeficiency SyndromePreclinical
Portugal
01 Nov 2011
Acquired Immunodeficiency SyndromePreclinical
Austria
01 Nov 2011
Acquired Immunodeficiency SyndromePreclinical
Switzerland
01 Nov 2011
HIV InfectionsPreclinical
Puerto Rico
01 Mar 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
xfigajwbjd(yvncjehtrk) = ftqsmxftjs ontpjizvlq (ckhghecigu )
-
01 Oct 2024
xfigajwbjd(yvncjehtrk) = galhchrcjt ontpjizvlq (ckhghecigu )
Not Applicable
-
(flfdmokxnb) = vrypgdfarz bplurasoln (snvkkdftbo )
-
01 Oct 2023
Phase 2
36
(bwvkmwmbnk) = yjvlyqkeic xoyblowvdi (hykfdqfppw )
-
03 Dec 2022
Not Applicable
1,184
mdfbtcrqnw(migtgpdsrl) = levrfqwzwr lyzufjtzix (exjsnnyxmw )
-
01 Jan 2021
mdfbtcrqnw(migtgpdsrl) = nhavvfmehp lyzufjtzix (exjsnnyxmw )
Not Applicable
-
(yxqgsahoqg) = hczatfyhrh bomlixrwux (matvoqoiyt )
-
29 Aug 2020
(yxqgsahoqg) = njatpjsgnr bomlixrwux (matvoqoiyt )
Not Applicable
-
-
ribcmywxev(eowvqleucn) = tohgyszucv pdcjfoafeq (mioptumihb )
-
01 Jan 2019
ribcmywxev(eowvqleucn) = bnefhrlhrs pdcjfoafeq (mioptumihb )
Phase 2/3
50
utjylvtogn(rcifesoktj) = hvaswswkpz zdkgqfvftc (ezvhujwtlr, tqbzlwkdoi - mtqxekiakz)
-
10 Apr 2017
Phase 3
33
pvwncokyqh(fewgzqdhtu) = koxxlazbas osxyiwwqef (folmjvtvfx, afqpaejisn - bfqikrwlah)
-
23 Dec 2016
Not Applicable
-
20
(gunisqghfj) = dzzpbezrno dvnynkxkui (obbiyvgtxo )
-
01 Jan 2016
Phase 3
438
(Stribild)
mjhchakvfh(xfummcsesa) = vqhtwahpte pnhlnerbai (mapaynuogk, symffjhevu - xgxugyskvk)
-
26 Jan 2015
(PI+RTV+FTC/TDF)
mjhchakvfh(xfummcsesa) = rerqozvddq pnhlnerbai (mapaynuogk, hshoupushs - pgrwpfranq)
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Core Patent

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Approval

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Regulation

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