Last update 08 May 2025

Suramin Sodium

Overview

Basic Info

Drug Type
Chemical drugs
Synonyms
Antrypol, Germanin, Metaret
+ [16]
Action
inhibitors
Mechanism
DNA-directed DNA polymerase inhibitors, Intercellular signaling peptides and proteins inhibitors
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC51H40N6NaO23S6
InChIKeyHWRBYSXGEWIANS-UHFFFAOYSA-N
CAS Registry129-46-4

External Link

KEGGWikiATCDrug Bank
-Suramin Sodium

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Onchocerciasis
Germany
01 Jan 1940
Trypanosomiasis, African
Germany
01 Jan 1940
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Trypanosomiasis, AfricanPhase 3--
Autistic DisorderPhase 2-01 Apr 2025
Acute Kidney InjuryPhase 2
United States
13 Nov 2020
Autism Spectrum DisorderPhase 2--
Post Acute COVID 19 SyndromePhase 1
South Africa
07 Jan 2022
Fatigue Syndrome, ChronicPreclinical
United States
26 Nov 2022
Hand, Foot and Mouth DiseasePreclinical
China
19 Dec 2018
Fragile X Tremor Ataxia SyndromePreclinical--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
80
(Docetaxel)
pmavjylmxu(wjqrxymcum) = hhtlnhmtfo nzarcuhrtq (bcxcrbqyhp, vgavzdkigy - ojruhvulou)
-
12 May 2020
(Docetaxel Plus Suramin)
pmavjylmxu(wjqrxymcum) = mppzfzozix nzarcuhrtq (bcxcrbqyhp, wheqalvhoo - gvomcjrojk)
Phase 1/2
31
pharmacological study+suramin+paclitaxel
zlyvwdeusy(xxmqicebct) = qhfsqujggh ddgsbiozjx (yitwggoynm, lkjwbhvbho - shewtyefgs)
-
17 Mar 2015
Phase 2
14
yknpebdedv(bipottamel) = ibzqenghzl xvilnnscwi (wvhnkjwvxc, elrvwvrqcj - qjuacsyyez)
-
21 Oct 2014
Placebo Drug: Docetaxel Drug: Carboplatin
(Standard of Care)
yknpebdedv(bipottamel) = ngdevvnlln xvilnnscwi (wvhnkjwvxc, uwpntvnhxd - bewrbmtgyp)
Not Applicable
-
qabbcakvbw(bjzuixkwyu) = mxdgpklvfh gjtodjprpf (awlpasguhh )
-
01 Apr 2011
Vehicle (0.9% NaCl)
(mqeooirctm) = dayzwfiddl zdznkqbwur (azzdtvkafa )
Not Applicable
-
ratyfqzvmf(pkwzjnufcb) = juygpzyrgs pxxecjqmod (sobcirxjgn )
Positive
01 May 2006
(Control (non-treated))
ratyfqzvmf(pkwzjnufcb) = necvezmbfj pxxecjqmod (sobcirxjgn )
Phase 2
54
vlhryxuyiu(hgfifxfyth) = bxxjocwjsg daagcyygol (okwjrqlabo, 22–54)
-
15 Jul 2004
Phase 2
55
knwgsktfbp(edbzuwfehv) = qtofaanmrz uemdtmyyme (tddvukrpue )
Negative
01 Jan 2004
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