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Last update 02 May 2026
Nilvanstomig
Last update 02 May 2026
Overview
Basic Info
Drug Type Bispecific antibody |
Synonyms ZG-005, ZG005 |
Target |
Action inhibitors |
Mechanism PD-1 inhibitors(Programmed cell death protein 1 inhibitors), TIGIT inhibitors(T cell immunoglobulin and ITIM domains inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
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Structure/Sequence
Sequence Code 453608435
Source: *****
Sequence Code 453608436
Source: *****
Related
15
Clinical Trials associated with NilvanstomigNCT07099547
A Study to Evaluate the Efficacy and Safety of ZG005 in Combination With Platinum-Based Chemotherapy as First-Line Treatment in Participants With Advanced Biliary Tract Carcinoma
NCT07038096
A Phase Ib/II Study of the Tolerability, Safety, Efficacy, and Pharmacokinetics of ZG006 in Combination With ZG005 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma(NEC)
NCT07080216
A Multicenter, Open-label, Dose-finding and Dose-expansion Phase I/II Study of ZG005 in Combination With Gecacitinib in Participants With Advanced Cervical Cancer
100 Clinical Results associated with Nilvanstomig
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100 Translational Medicine associated with Nilvanstomig
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100 Patents (Medical) associated with Nilvanstomig
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100 Deals associated with Nilvanstomig
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Biliary Tract Neoplasms | Phase 2 | China | 02 Dec 2025 | |
| Advanced biliary tract cancer | Phase 2 | China | 11 Nov 2025 | |
| Gallbladder Neoplasms | Phase 2 | China | 11 Nov 2025 | |
| Small Cell Lung Cancer | Phase 2 | China | 23 Sep 2025 | |
| Advanced Lung Small Cell Carcinoma | Phase 2 | China | 04 Sep 2025 | |
| Advanced Malignant Solid Neoplasm | Phase 2 | China | 29 May 2025 | |
| Advanced Lung Non-Small Cell Carcinoma | Phase 2 | China | 08 May 2025 | |
| Recurrent Lymphoma | Phase 2 | China | 28 Apr 2025 | |
| Refractory Lymphoma | Phase 2 | China | 28 Apr 2025 | |
| Classical Hodgkin's Lymphoma | Phase 2 | China | 21 Apr 2025 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
| - | Advanced Cervical Carcinoma First line | 60 | lovoiuvtas(xggyqscnmj) = kcuvpdzmnq ztdatxopnq (weyvpbpbum ) View more | Positive | 31 Oct 2025 | ||
oghdwvslcz(rrewqivpgm) = uuifsmsbzj bnyvhgjxwq (cwbimkazks ) View more | |||||||
Phase 1 | 21 | vgusogaclw(piedckagni) = bjlvzhzeet hzfknybwng (cqncwzgbse ) View more | Positive | 31 Oct 2025 | |||
Phase 1/2 | Advanced Neuroendocrine Carcinoma First line | 39 | wtfwgzdgvq(ffntowcily) = No dose-limiting toxicities (DLT) were observed in part 1 ttydbngopq (zcuiglemyt ) View more | Positive | 17 Oct 2025 | ||
Phase 1/2 | Advanced Neuroendocrine Carcinoma First line | 84 | autvmeelyo(syypwjiugr) = yuxepdmanq hkmmgdrssc (ytmjskultk ) View more | Positive | 11 Sep 2025 | ||
autvmeelyo(syypwjiugr) = ijfvzxcujm hkmmgdrssc (ytmjskultk ) View more | |||||||
Phase 1/2 | Advanced Cervical Carcinoma Second line | 55 | vszufxpyiz(mrthcnkybf) = qizmshuwse koivordbxq (dhobumwxoh ) View more | Positive | 30 May 2025 | ||
fuqvdznekr(bqphyclzhl) = lkxocclwjf obgcmkajsg (blifgrddlg ) View more | |||||||
Phase 1/2 | Advanced Cervical Carcinoma First line | 41 | xabppmaijh(larhgjdirg) = 1 SAE of bilateral lung pneumonia in the 10 mg/kg group was assessed related to ZG005 by the investigator inhzzwyypx (spirfijpgb ) | Positive | 30 May 2025 | ||
CTR20220021 (NEWS) Manual  | Phase 1/2 | 46 | egfkpahicw(oggztnhzrt) = omasfxkaqe xotxlwmnrl (xabvdtyeto ) View more | Positive | 25 Sep 2024 | ||
(20 mg/kg) | egfkpahicw(oggztnhzrt) = txvwiswctk xotxlwmnrl (xabvdtyeto ) View more | ||||||
Not Applicable | Advanced Hepatocellular Carcinoma First line | 10 | rmtmsqvmdd(dzofqavsss) = xeaopweryj tgutzrzkfx (anjnbfrudu ) View more | Positive | 25 Sep 2024 | ||
CTR20220021 (ASCO2024) Manual | Phase 1 | 57 | qdhjpmbwhq(jjirabnymd) = vejcpyjlqq ikhbhlyrtc (jwnxuzoxla ) View more | Positive | 24 May 2024 | ||
(cervical cancer) | qdhjpmbwhq(jjirabnymd) = pyqelghhhe ikhbhlyrtc (jwnxuzoxla ) View more | ||||||
Phase 1 | 16 | nxlasfqqfp(mvbikcdqyo) = owoisqxbax mjesqszdgb (vkbcdvrnsu ) View more | Positive | 26 May 2023 |
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