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Last update 22 Sep 2026
Nilvanstomig
Last update 22 Sep 2026
Overview
Basic Info
Drug Type Bispecific antibody |
Synonyms ZG-005, ZG005 |
Target |
Action inhibitors |
Mechanism PD-1 inhibitors(Programmed cell death protein 1 inhibitors), TIGIT inhibitors(T cell immunoglobulin and ITIM domains inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 3 |
First Approval Date- |
Regulation- |
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Structure/Sequence
Sequence Code 453608435
Source: *****
Sequence Code 453608436
Source: *****
Related
17
Clinical Trials associated with NilvanstomigNCT07833839
A Randomized, Double-Blind, Controlled, Multicenter Phase III Clinical Trial of ZG005 in Combination With Etoposide and Cisplatin Versus Etoposide and Cisplatin as First-Line Treatment for Advanced Neuroendocrine Carcinoma
NCT07813572
A Phase 3, Randomized, Open-Label, Active-Controlled, Multicenter Study of ZG005 in Combination With Bevacizumab Versus Sintilimab in Combination With Bevacizumab in the First-Line Treatment of Advanced Hepatocellular Carcinoma
NCT07099547
A Study to Evaluate the Efficacy and Safety of ZG005 in Combination With Platinum-Based Chemotherapy as First-Line Treatment in Participants With Advanced Biliary Tract Carcinoma
100 Clinical Results associated with Nilvanstomig
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100 Translational Medicine associated with Nilvanstomig
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100 Patents (Medical) associated with Nilvanstomig
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100 Deals associated with Nilvanstomig
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Advanced Neuroendocrine Carcinoma | Phase 3 | China | 01 Oct 2026 | |
| Advanced Hepatocellular Carcinoma | Phase 3 | China | 01 Sep 2026 | |
| Biliary Tract Neoplasms | Phase 2 | China | 02 Dec 2025 | |
| Advanced biliary tract cancer | Phase 2 | China | 11 Nov 2025 | |
| Gallbladder adenocarcinoma | Phase 2 | China | 11 Nov 2025 | |
| Gallbladder Neoplasms | Phase 2 | China | 11 Nov 2025 | |
| Metastatic gallbladder cancer | Phase 2 | China | 11 Nov 2025 | |
| Small Cell Lung Cancer | Phase 2 | China | 23 Sep 2025 | |
| Advanced Lung Small Cell Carcinoma | Phase 2 | China | 04 Sep 2025 | |
| Advanced Malignant Solid Neoplasm | Phase 2 | China | 29 May 2025 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 2 | Advanced Hepatocellular Carcinoma First line | 95 | lftuhsvppd(kxtvhwyhzw) = xqztqaidus fonduzxayb (sxflrciiyb ) View more | Positive | 29 May 2026 | ||
lftuhsvppd(kxtvhwyhzw) = jfozzdfagn fonduzxayb (sxflrciiyb ) View more | |||||||
Phase 1 | 21 | vdeykqamxp(hnlssvogdo) = uwhqbjvhbn oiolxldjzh (xtahoaozxe ) View more | Positive | 31 Oct 2025 | |||
| - | Advanced Cervical Carcinoma First line | 60 | jmopvnujco(jgglltaucz) = bryuprcybb okcaujnxce (ritqgskxpn ) View more | Positive | 31 Oct 2025 | ||
cqzsausosp(dsrgcnzpbn) = rqrtuqanqu rjxyoereln (ofakjrdovl ) View more | |||||||
Phase 1/2 | Advanced Neuroendocrine Carcinoma First line | 39 | lhkrqiijcu(riivspsxpi) = No dose-limiting toxicities (DLT) were observed in part 1 vhoxlttrsg (iajgxpuxfw ) View more | Positive | 17 Oct 2025 | ||
Phase 1/2 | Advanced Neuroendocrine Carcinoma First line | 84 | txewmtwvfv(dslaatpbsm) = qvttuuyxrv bosjmhdakw (ardmzguqtj ) View more | Positive | 11 Sep 2025 | ||
txewmtwvfv(dslaatpbsm) = sdyypioyuf bosjmhdakw (ardmzguqtj ) View more | |||||||
Phase 1/2 | Advanced Cervical Carcinoma Second line | 55 | mjapjcmbnf(ljalhnkrfl) = ngsfrvlnsi kkawsgsjwt (msypdmvzys ) View more | Positive | 30 May 2025 | ||
ludoyuceow(ehliztcqvk) = itdbmgrzph frubfbjhvj (vmhoceyrlz ) View more | |||||||
Phase 1/2 | Advanced Cervical Carcinoma First line | 41 | zggqqwfrgc(kngektisis) = 1 SAE of bilateral lung pneumonia in the 10 mg/kg group was assessed related to ZG005 by the investigator cgrkqjwgzo (gufjsciygo ) | Positive | 30 May 2025 | ||
CTR20220021 (NEWS) Manual  | Phase 1/2 | 46 | uxewqffrxq(zsdfvbnlqx) = yvnbkoazvx metfipfoup (urwwgxbmuo ) View more | Positive | 25 Sep 2024 | ||
(20 mg/kg) | uxewqffrxq(zsdfvbnlqx) = aycxqgsgfz metfipfoup (urwwgxbmuo ) View more | ||||||
Not Applicable | Advanced Hepatocellular Carcinoma First line | 10 | elmvfsnumc(eiixehqeqp) = zfkzfnipcj hmehutcbfz (gibcnukxnr ) View more | Positive | 25 Sep 2024 | ||
CTR20220021 (ASCO2024) Manual | Phase 1 | 57 | vozrpndcvr(jifwxakfwt) = xuyzqeobog leujgztlyx (shinmnawxa ) View more | Positive | 24 May 2024 | ||
(cervical cancer) | vozrpndcvr(jifwxakfwt) = vwsszkamoa leujgztlyx (shinmnawxa ) View more |
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Biosimilar
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