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Last update 16 Jul 2026
Nilvanstomig
Last update 16 Jul 2026
Overview
Basic Info
Drug Type Bispecific antibody |
Synonyms ZG-005, ZG005 |
Target |
Action inhibitors |
Mechanism PD-1 inhibitors(Programmed cell death protein 1 inhibitors), TIGIT inhibitors(T cell immunoglobulin and ITIM domains inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
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Structure/Sequence
Sequence Code 453608435
Source: *****
Sequence Code 453608436
Source: *****
Related
15
Clinical Trials associated with NilvanstomigNCT07099547
A Study to Evaluate the Efficacy and Safety of ZG005 in Combination With Platinum-Based Chemotherapy as First-Line Treatment in Participants With Advanced Biliary Tract Carcinoma
NCT07080216
A Multicenter, Open-label, Dose-finding and Dose-expansion Phase I/II Study of ZG005 in Combination With Gecacitinib in Participants With Advanced Cervical Cancer
NCT07038096
A Phase Ib/II Study of the Tolerability, Safety, Efficacy, and Pharmacokinetics of ZG006 in Combination With ZG005 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma(NEC)
100 Clinical Results associated with Nilvanstomig
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100 Translational Medicine associated with Nilvanstomig
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100 Patents (Medical) associated with Nilvanstomig
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100 Deals associated with Nilvanstomig
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Biliary Tract Neoplasms | Phase 2 | China | 02 Dec 2025 | |
| Advanced biliary tract cancer | Phase 2 | China | 11 Nov 2025 | |
| Gallbladder adenocarcinoma | Phase 2 | China | 11 Nov 2025 | |
| Gallbladder Neoplasms | Phase 2 | China | 11 Nov 2025 | |
| Metastatic gallbladder cancer | Phase 2 | China | 11 Nov 2025 | |
| Small Cell Lung Cancer | Phase 2 | China | 23 Sep 2025 | |
| Advanced Lung Small Cell Carcinoma | Phase 2 | China | 04 Sep 2025 | |
| Advanced Malignant Solid Neoplasm | Phase 2 | China | 29 May 2025 | |
| Advanced Lung Non-Small Cell Carcinoma | Phase 2 | China | 08 May 2025 | |
| Recurrent Lymphoma | Phase 2 | China | 28 Apr 2025 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 2 | Advanced Hepatocellular Carcinoma First line | 95 | gdvpxtrepm(xyugaftelr) = sausxrlqfy pbierglzcw (cqutciejil ) View more | Positive | 29 May 2026 | ||
gdvpxtrepm(xyugaftelr) = paqwgsgefl pbierglzcw (cqutciejil ) View more | |||||||
| - | Advanced Cervical Carcinoma First line | 60 | smauhzqncf(jcnsddwvqz) = srvchbglcd rscorfnajt (iygwyhzrqz ) View more | Positive | 31 Oct 2025 | ||
murrwqvaea(jyzuysmbzh) = yycuhgxrwj muqbtznnbd (ozlvzanyhg ) View more | |||||||
Phase 1 | 21 | bwjarjvdyx(dqzenekacl) = ioygmkwfic byrwadhtaj (bieemjycjt ) View more | Positive | 31 Oct 2025 | |||
Phase 1/2 | Advanced Neuroendocrine Carcinoma First line | 39 | rtbhiesdxx(eyhvpukzrs) = No dose-limiting toxicities (DLT) were observed in part 1 zcvdlmxoax (njyflgbmwr ) View more | Positive | 17 Oct 2025 | ||
Phase 1/2 | Advanced Neuroendocrine Carcinoma First line | 84 | thhafgyawa(sqcsnrbycf) = mwttjjcopg soiccwwwda (prsltupaax ) View more | Positive | 11 Sep 2025 | ||
thhafgyawa(sqcsnrbycf) = onwdcrjjbp soiccwwwda (prsltupaax ) View more | |||||||
Phase 1/2 | Advanced Cervical Carcinoma Second line | 55 | gusywusoql(szxlhcyrwc) = qsrnjozrze uolfmbetsh (wclltzhcnv ) View more | Positive | 30 May 2025 | ||
lcggsawkla(nfvecxlfwi) = swexuyzqtt nakobrfjfy (ndagaldasj ) View more | |||||||
Phase 1/2 | Advanced Cervical Carcinoma First line | 41 | kwvkmbyoue(lkqvvgyfwr) = 1 SAE of bilateral lung pneumonia in the 10 mg/kg group was assessed related to ZG005 by the investigator rsgbqkzoxx (xnrbnnnazv ) | Positive | 30 May 2025 | ||
CTR20220021 (NEWS) Manual  | Phase 1/2 | 46 | rebhwhtldy(lnbahkasgs) = fvcyjdtruu bmiwcxqetn (tucqbxnzwa ) View more | Positive | 25 Sep 2024 | ||
(20 mg/kg) | rebhwhtldy(lnbahkasgs) = lirirsdkjn bmiwcxqetn (tucqbxnzwa ) View more | ||||||
Not Applicable | Advanced Hepatocellular Carcinoma First line | 10 | qrybptqmff(kdsbsiyltk) = lrqsadkpln iorawxjxko (emeszmtvgb ) View more | Positive | 25 Sep 2024 | ||
CTR20220021 (ASCO2024) Manual | Phase 1 | 57 | abhcuflasf(udpbzitlim) = dhaiqkhwck kbyebdqrir (pysorqlhak ) View more | Positive | 24 May 2024 | ||
(cervical cancer) | abhcuflasf(udpbzitlim) = jprobhwhxd kbyebdqrir (pysorqlhak ) View more |
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Biosimilar
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