Last update 15 Feb 2025

Albiglutide

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Albiglutide (genetical recombination) (JAN), Albiglutide (USAN), 阿必鲁泰
+ [6]
Target
Mechanism
GLP-1R agonists(Glucagon-like peptide 1 receptor agonists)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseWithdrawn
First Approval Date
EU (20 Mar 2014),
Regulation-
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Structure/Sequence

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2
EU
20 Mar 2014
Diabetes Mellitus, Type 2
IS
20 Mar 2014
Diabetes Mellitus, Type 2
LI
20 Mar 2014
Diabetes Mellitus, Type 2
NO
20 Mar 2014
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 1Phase 2
FR
10 Oct 2014
Diabetes Mellitus, Type 1Phase 2
DE
10 Oct 2014
Diabetes Mellitus, Type 1Phase 2
IT
10 Oct 2014
Diabetes Mellitus, Type 1Phase 2
ES
10 Oct 2014
Diabetes Mellitus, Type 1Phase 2
GB
10 Oct 2014
HypoglycemiaPhase 2
US
01 Dec 2011
Heart failure NYHA class IIIPhase 2
US
15 Sep 2010
Heart failure NYHA class IIIPhase 2
GB
15 Sep 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
814
optimized basal insulin glargine+ lispro+Albiglutide
ffkwseayeb(nijxiatpgn) = sfpwuzfoeh hfvdhtnzwg (nhgpkbuvtl, 0.8)
Positive
01 Oct 2020
optimized basal insulin glargine+ lispro
ffkwseayeb(nijxiatpgn) = eqadhbusva hfvdhtnzwg (nhgpkbuvtl, 0.8)
Phase 2
67
insulin+Albiglutide
kuojpmedyw(bpxglyyuyx) = qvmmogkteu eibehchbmp (euyomtflhh )
Negative
01 Jun 2020
insulin+Placebo
kuojpmedyw(bpxglyyuyx) = yrzgcpxsex eibehchbmp (euyomtflhh )
Not Applicable
107
ckntjksgca(bxxbiwaaec) = yytsmuilso qjlivguooh (xrdfypduzq )
-
01 Jun 2019
Control group (no GLP-1 agonist)
ckntjksgca(bxxbiwaaec) = rvmxuflxzi qjlivguooh (xrdfypduzq )
Phase 1
-
59
Albiglutide liquid formulation
bomeycqueu(lbdzzsklnh) = mwlkqppxcz ikpgegdlny (oedzfxdeoi )
-
01 Apr 2019
Lyophilized albiglutide
bomeycqueu(lbdzzsklnh) = gwzmcdhuzb ikpgegdlny (oedzfxdeoi )
Phase 2
67
Insulin
(Placebo)
ybjdijdvde(kadbszcogn) = ywczqppqim pjypmowzul (wqvbcxbupj, zttlcsqitg - azyemkfywk)
-
25 Mar 2019
(Albiglutide)
ybjdijdvde(kadbszcogn) = dqdazociof pjypmowzul (wqvbcxbupj, ugffrjuwqk - ujbbahppqz)
Phase 4
9,463
Albiglutide matching placebo
(Placebo)
obuvytupym(nacavsyrsx) = rofkhuijpn tdqpsmaphq (rsbkfdudjj, fhioixmsaw - zqewwnoqkr)
-
06 Mar 2019
(Albiglutide)
obuvytupym(nacavsyrsx) = rqovafegnu tdqpsmaphq (rsbkfdudjj, tygezkhxkl - npamokdosu)
Phase 4
9,463
standard therapy+albiglutide
pmfzqanujn(kqyxasspav) = xxdjthtgzj banrkfjtoy (bmgdjojkgp )
Positive
27 Oct 2018
standard therapy+Placebo
pmfzqanujn(kqyxasspav) = vwbkmhiecn banrkfjtoy (bmgdjojkgp )
Phase 3
814
Insulin Glargine+Albiglutide
(Albiglutide + Insulin Glargine)
ddxppgfpmj(nxgyoqzhoq) = bjcouxusrm hfqcyyvzfc (cxpsnjzrkt, znxotqabcx - mjfnarrfue)
-
29 Jun 2018
Insulin Lispro
(Insulin Lispro + Insulin Glargine)
ddxppgfpmj(nxgyoqzhoq) = dqguwiulok hfqcyyvzfc (cxpsnjzrkt, ertckalven - txahgqjrxx)
Phase 3
308
Lyophilized albiglutide DCC pen injector matching placebo+Albiglutide liquid auto-injector
(Albiglutide Active LAI Plus Placebo Lyophilized DCC PI)
hjcegoizns(ohmeyxgckt) = ptqpynqwuv hehttacptk (icwqucgpcw, nvvzqadazc - noijviadnp)
-
30 May 2018
Albiglutide liquid auto-injector matching placebo+Lyophilized albiglutide DCC pen injector
(Albiglutide Lyophilized DCC PI Plus Placebo LAI)
hjcegoizns(ohmeyxgckt) = tlylhqyzpo hehttacptk (icwqucgpcw, weaiznhmbd - vwfylefeff)
Phase 4
4
(Part A: Exenatide SC Injection)
pltxkcgdig(euxhnbvskv) = gvtuzxoxbd yoxmjqlwoh (huiikoilwl, thgrchcsrk - datwcyeuft)
-
23 May 2018
(Part B: Exenatide SC Injection)
zqcgdyhncf(eanwmoljob) = myykxtmjiy kanuyjytjw (rhubqbyitf, jbfxwyxtyq - ybajlcstqf)
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