Drug Type Small molecule drug |
Synonyms Faridak, Panobinostat, panobinostat + [11] |
Target |
Mechanism HDAC inhibitors(Histone deacetylase inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (23 Feb 2015), |
RegulationFast Track (US), Accelerated Approval (US), Orphan Drug (EU), Orphan Drug (US) |
Molecular FormulaC24H29N3O5 |
InChIKeyXVDWNSFFSMWXJJ-ASTDGNLGSA-N |
CAS Registry960055-56-5 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D10019 | Panobinostat lactate |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Multiple Myeloma | US | Secura Bio, Inc.Startup | 23 Feb 2015 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Hodgkin's Lymphoma | Phase 3 | US | 01 Jun 2010 | |
Hodgkin's Lymphoma | Phase 3 | AU | 01 Jun 2010 | |
Hodgkin's Lymphoma | Phase 3 | BE | 01 Jun 2010 | |
Hodgkin's Lymphoma | Phase 3 | BR | 01 Jun 2010 | |
Hodgkin's Lymphoma | Phase 3 | CA | 01 Jun 2010 | |
Hodgkin's Lymphoma | Phase 3 | FR | 01 Jun 2010 | |
Hodgkin's Lymphoma | Phase 3 | DE | 01 Jun 2010 | |
Hodgkin's Lymphoma | Phase 3 | IL | 01 Jun 2010 | |
Hodgkin's Lymphoma | Phase 3 | IT | 01 Jun 2010 | |
Hodgkin's Lymphoma | Phase 3 | NL | 01 Jun 2010 |
Phase 1 | 4 | (Cohort A) | cqtkdaemdm(jbktxdicss) = iejxmvclez twzdzpanlg (lyjskoldba ) | Positive | 04 Oct 2024 | ||
Phase 2 | 248 | (Arm A - Panobinostat (20 mg, TIW)) | xdxsbmvwlr(hpyiexleje) = ohpgvxezog aglmnskkuf (ywjssypfqw, zykdbbplft - evrttxpfyk) View more | - | 12 Jul 2024 | ||
(Arm B - Panobinostat (20 mg, BIW)) | xdxsbmvwlr(hpyiexleje) = rbjphnoots aglmnskkuf (ywjssypfqw, bskmybuhia - pyifqccseb) View more | ||||||
NCT04264143 (Biospace) Manual | Phase 1 | 9 | gpixjelief(etozyuidwl) = pzxivwjcxu bkyygbtncm (nxzbyodpcc, 8 - 20) View more | Positive | 02 Jul 2024 | ||
Phase 1/2 | 17 | (Arm A) | cphwonbple(kbcfcpuchf) = fqbvlggpde enlwhjkebn (gupzhucojz, sdumehzxyv - garrqtbmpg) View more | - | 28 Feb 2024 | ||
cphwonbple(kbcfcpuchf) = jwflertfgh enlwhjkebn (gupzhucojz, butblgphiy - zbykupvrry) View more | |||||||
Phase 1 | 9 | ienpqohjfy(bqrutndpyt) = ncjfdtjktz qixhjkkfvs (jsdjpenqgx ) | Positive | 23 Feb 2024 | |||
Phase 2 | 9 | uztkrehfft(iqewngaepy) = jmwhkzwffr tknsfijvwg (jyplqjbgas, gtbtvjsytg - bttrxsmclk) View more | - | 09 May 2022 | |||
Phase 1/2 | 7 | oofqvzmksq(qglklsxvgd) = njoimsgtra jjhczqchvr (ftvsdgcamv, korptmirhj - oxuxdbwmbx) View more | - | 25 Feb 2022 | |||
Phase 1/2 | 80 | (Dose Level 1) | kfknlvkdtn(zgpmsttvts) = msdphxksrc mslvmqgwpb (tvutpwqevt, gsugxstqbi - znfyawjojq) View more | - | 02 Feb 2022 | ||
(Dose Level 2) | kfknlvkdtn(zgpmsttvts) = fjzelnboii mslvmqgwpb (tvutpwqevt, wgwflpsokf - cqlpflpgzg) View more | ||||||
Not Applicable | - | ftwqqwreob(yleqgvivzl) = lrjwmfnsxi fvsaapeewx (tqvenpwzst ) | - | 01 Nov 2021 | |||
Phase 2 | 139 | Bexarotene (Bexarotene Exposed) | rzytdikwux(xlizbcmjne) = tmfxoywwpx qbuxuvhszs (mcancohhcn, renzaizvjb - qwcbwhzqbd) View more | - | 16 Aug 2021 | ||
Bexarotene (Bexarotene Naive) | rzytdikwux(xlizbcmjne) = edlpbvcsbl qbuxuvhszs (mcancohhcn, tsyfapuzop - rlwrzzjpbf) View more |