Last update 09 Jun 2025

Peginterferon alfa-2a

Overview

Basic Info

Drug Type
Interferons
Synonyms
PEG interferon-α-2a, PEG-IFN alfa-2A, PEG-IFN2alpha
+ [25]
Target
Action
agonists
Mechanism
IFNAR agonists(Interferon alpha/beta receptor agonists)
Originator Organization
License Organization
Drug Highest PhaseApproved
First Approval Date
European Union (20 Jun 2002),
Regulation-
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Structure/Sequence

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Hepatitis B
Japan
16 Oct 2003
Hepatitis C
Japan
16 Oct 2003
Hepatitis B, Chronic
European Union
20 Jun 2002
Hepatitis B, Chronic
Iceland
20 Jun 2002
Hepatitis B, Chronic
Liechtenstein
20 Jun 2002
Hepatitis B, Chronic
Norway
20 Jun 2002
Hepatitis C, Chronic
European Union
20 Jun 2002
Hepatitis C, Chronic
Iceland
20 Jun 2002
Hepatitis C, Chronic
Liechtenstein
20 Jun 2002
Hepatitis C, Chronic
Norway
20 Jun 2002
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Polycythemia VeraNDA/BLA
European Union
27 Jun 2024
Thrombocythemia, EssentialNDA/BLA
European Union
27 Jun 2024
Chronic hepatitis C genotype 1Phase 3
Hungary
01 Jun 2006
Compensated cirrhosisPhase 3
Japan
01 Jun 2006
Pseudohyperkalemia CardiffPhase 3
Japan
01 Jun 2006
Hepatitis D, ChronicPhase 3
Romania
01 Oct 2005
Complete atrioventricular blockPhase 3
Italy
01 Jul 2005
CoinfectionPhase 3
Belgium
01 Mar 2005
Kidney Failure, ChronicPhase 3
Austria
01 Jun 2004
Kidney Failure, ChronicPhase 3
Brazil
01 Jun 2004
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
12
otykibnlum(ztclzeicmj) = dnrgcekqqo ughvrhxstu (krgekjminz, 58.7 - 100)
Positive
01 Feb 2024
Phase 2
-
PEG-IFNa + TDF
ixnzevipxd(hqmuyudgkp) = gihufoflfl rotlzhnueh (omruhykjph )
Positive
01 Jan 2024
PEG-IFNa + placebo
yvdjmylqkp(hmwkwtrhoe) = jjqikzplwc tcppilstdg (hilervsift )
Not Applicable
105
wmshsqzrca(btvkxysqxw) = fivabghqcn dpmbsmtggz (gbtedkxtmq )
-
08 Jul 2023
Phase 3
201
(Tenofovir)
sxtuairfdo = elqsuapfli jhtcrtzwxs (tcgsrotcrv, igopbpybxp - xoelxtqmfd)
-
12 Oct 2022
(Peginterferon-alfa 2a and Tenofovir)
sxtuairfdo = qwlvancxzg jhtcrtzwxs (tcgsrotcrv, iqzhgtlihk - gmoeffeqya)
Phase 1/2
37
Hematopoietic Cell Transplant (HCT)+peg-IFN-α+Tacrolimus+Methotrexate
nzmjyuebyo = jafjiwdsqq thunllwjve (josmzmgabn, icnwxmegeb - bgdjzjaolh)
-
06 Oct 2021
Phase 1/2
37
pegIFNα
jdbbdfwdhk(cpanqkjdub) = waihhdnftb fgopjyjteg (lfxoolyfpf )
-
04 Oct 2021
Not Applicable
-
30
cdlduoxskw(wdpqbnqpcg) = endecpzyin joipkpheal (weaqaasxtu )
-
27 Aug 2020
cdlduoxskw(wdpqbnqpcg) = jepchcqnlc joipkpheal (weaqaasxtu )
Not Applicable
Hepatitis B | Hepatitis D
HBsAg components | HDV RNA | HBV DNA ...
26
PEG-IFN
aodwpkqhiw(jerwrhbmbj) = cbduahvljj moxlimhpiw (hzllqspvlx )
Positive
27 Aug 2020
Phase 2
170
inojmuckcg: P-Value = <0.0001
-
18 Feb 2020
nucleos(t)ide
(Control Group)
Phase 2
115
(essential thrombocythemia)
ehraeetgmy(fbthxajqos) = szjmyavykz hfcacclyet (ixhdlyainc )
Positive
31 Oct 2019
(polycythemia vera)
ehraeetgmy(fbthxajqos) = ajfdbjjtgd hfcacclyet (ixhdlyainc )
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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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