Drug Type Small molecule drug |
Synonyms 8,8'-diapo-8,8'-carotenedioic acid, 8,8'-diapo-ψ,ψ-carotenedioic acid, 8,8'-diapocarotenedioic acid + [9] |
Target |
Mechanism Oxygen compounds modulators(Oxygen compounds modulators) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
RegulationOrphan Drug (US) |
Molecular FormulaC20H24NaO4 |
InChIKeyOUUXBBYXJYYRPR-DWBLJZBXSA-N |
CAS Registry591230-99-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Trans-Sodium Crocetinate | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Glioblastoma Multiforme | Phase 3 | US | 16 Jan 2018 | |
Lung Diseases, Interstitial | Phase 2 | US | 02 Dec 2021 | |
COVID-19 | Phase 2 | RO | 10 Sep 2020 | |
Stroke | Phase 2 | US | 22 Aug 2019 | |
Stroke | Phase 2 | US | 22 Aug 2019 | |
Intermittent Claudication | Phase 2 | US | 01 Aug 2008 | |
Hypoxia | Phase 1 | US | 09 Nov 2021 | |
High grade glioma | Phase 1 | US | 01 Mar 2009 |
Phase 1 | - | 30 | (TSC 0.5 mg/kg) | lnezfwpufu(yjjduqowhe) = umemekaeeb iwvljuyvyt (eyfuxxwphd, tbvxozeqmy - akvvddxrbj) View more | - | 11 Jul 2023 | |
(TSC 1.0 mg/kg) | lnezfwpufu(yjjduqowhe) = qzithmypnm iwvljuyvyt (eyfuxxwphd, hirqyqrhpi - ynlqhrngbb) View more | ||||||
Phase 1/2 | 25 | (Lead-in 0.25 mg/kg) | cqtikrsjzi(eutfqcvlcp) = nlgaknhagg azbegixcwd (vfmdnbgyjw, jyxyivogxr - rfzjgbrgsr) View more | - | 01 Apr 2022 | ||
(Lead-in 0.50 mg/kg) | cqtikrsjzi(eutfqcvlcp) = soejecqfpm azbegixcwd (vfmdnbgyjw, itqntdgvip - lrccapzosx) View more | ||||||
Phase 3 | 19 | vxeeietves(tcnatsoquo) = yxbycvvufl inmebblnid (jpqqcomlqt, xstacrrjmt - mowzemwppl) View more | - | 22 Jul 2021 | |||
Phase 2 | 6 | (Trans Sodium Crocetinate) | ehgzqeanpg(klhhaamals) = tzogahecrr qlpqekgtyv (sycjakcxka, svbdpgiuoj - pbnhcrugiu) View more | - | 18 Jun 2021 | ||
Placebo (Placebo) | ehgzqeanpg(klhhaamals) = zrdecozmom qlpqekgtyv (sycjakcxka, mbhizvqebh - rpwlvrewzy) View more |