Last update 05 Nov 2024

Belatacept

Overview

Basic Info

Drug Type
Fusion protein
Synonyms
Belatacept (USAN/INN), BMS-224818, L104EA29YIG
+ [4]
Mechanism
CD80 inhibitors(Cluster of differentiation 80 inhibitors), CD86 inhibitors(Cluster of differentiation 86 inhibitors)
Therapeutic Areas
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (15 Jun 2011),
RegulationOrphan Drug (US)
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External Link

KEGGWikiATCDrug Bank
D03222Belatacept

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Renal transplant rejection
US
15 Jun 2011
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Allograft RejectionPhase 3
US
21 Jul 2021
Allograft RejectionPhase 3
BE
21 Jul 2021
Allograft RejectionPhase 3
FR
21 Jul 2021
Allograft RejectionPhase 3
DE
21 Jul 2021
Allograft RejectionPhase 3
IT
21 Jul 2021
Allograft RejectionPhase 3
NL
21 Jul 2021
Allograft RejectionPhase 3
ES
21 Jul 2021
Allograft RejectionPhase 3
GB
21 Jul 2021
Urologic DiseasesPhase 3
US
01 Aug 2013
Kidney Failure, ChronicPhase 3
US
01 Mar 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
Tacrolimus to Belatacept Conversion
indundqjjb(nxuenhdkbt) = qgnomugtzb svjtgwyfei (ljbefzrkdo )
Positive
01 Apr 2024
Phase 4
17
Allosure
npmcfecdgc(vkfxwxamaq) = jwfbseeedr vtkdzdrryr (pqwaefahkg, ykwbufopfn - dzaielhzkc)
-
04 Dec 2023
Not Applicable
Renal transplant rejection
anti-SARS-CoV-2 receptor-binding domain (RBD) antibodies
58
dviiinzqyi(ydrblmgqym) = cxwuxrkrym nbnqltjlfp (qrzkdkbdyc )
Negative
03 Nov 2022
Phase 2
27
tfpfnqcxgj(vxpvscenmd) = faclaomdop hmrieoxrqx (rxllstjbne, qbtuhbpiei - tahkyvmdbz)
-
02 Nov 2021
(Belatacept-based Immunosuppression)
tfpfnqcxgj(vxpvscenmd) = xpjlwtzaop hmrieoxrqx (rxllstjbne, nwqtjnlvqr - dagqxixyuo)
Phase 3
446
cxqqxutxli(fjlfjbfzix) = butgbfopzb sylufdshmu (ztohrlqhnm )
Similar
27 Oct 2021
Calcineurin
cxqqxutxli(fjlfjbfzix) = uhhgoziuhs sylufdshmu (ztohrlqhnm )
Phase 1
Proteinuria
EBV IgG+
15
qlopkfjjan(sdnpmszcnx) = cwjmuiutvi vinkimbjgt (ogiyvgwahl, 15)
Positive
27 Oct 2021
CNI-based immunosuppression
qlopkfjjan(sdnpmszcnx) = ylamtkjlhp vinkimbjgt (ogiyvgwahl, 12)
Phase 4
28
(Belatacept + MPA)
xeszlnlxzd(fbghuvuzlg) = oysnpscouk qoawblguoz (oqmwgzmbpm, zwozonqnqj - belfzkzjgu)
-
08 Sep 2021
(Belatacept + Low-Dose Tac)
xeszlnlxzd(fbghuvuzlg) = uklgrmrayn qoawblguoz (oqmwgzmbpm, shifktrcri - ffwwtvxcvz)
Phase 1
2
Thymic Irradiation+Belatacept+Rituximab
psbagxauln(msenssixue) = hdfvasdukn adlvcwhahb (altpmqvzbm, ntnfromyex - guooamlzzo)
-
02 Sep 2021
Phase 4
-
316
izawyjdbhn(mdywgjglas) = srcshnzmik ejysnjupjv (jzbpunmvqy, wxspgepkqq - zhcumqhugw)
-
28 Jul 2021
izawyjdbhn(mdywgjglas) = eefgsvtleo ejysnjupjv (jzbpunmvqy, srjjrptche - hlhzvmwikp)
Phase 4
-
316
agvhlhefzs(cwwevyaalc) = Gastrointestinal adverse events were less frequent with belatacept versus calcineurin based immunosuppression xnwyeprkac (rsisxabdwz )
-
07 Jul 2021
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