Drug Type Small molecule drug |
Synonyms Dapagliflozin Propanediol Monohydrate/Metformin Hydrochloride, Dapagliflozin/metformin, Dapagliflozin/metformin FDC + [13] |
Target |
Action activators, inhibitors |
Mechanism PRKAB1 activators(Protein kinase AMP-activated non-catalytic subunit beta 1 activators), SGLT2 inhibitors(Sodium/glucose cotransporter 2 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date European Union (16 Jan 2014), |
Regulation- |
Molecular FormulaC28H47Cl2N5O9 |
InChIKeyFRSHUOVOWUSWFQ-SOZVNENWSA-N |
CAS Registry2446159-54-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Diabetes Mellitus, Type 1 | European Union | 15 Nov 2015 | |
Diabetes Mellitus, Type 1 | Iceland | 15 Nov 2015 | |
Diabetes Mellitus, Type 1 | Liechtenstein | 15 Nov 2015 | |
Diabetes Mellitus, Type 1 | Norway | 15 Nov 2015 | |
Diabetes Mellitus | Australia | 18 Jul 2014 | |
Diabetes Mellitus, Type 2 | European Union | 16 Jan 2014 | |
Diabetes Mellitus, Type 2 | Iceland | 16 Jan 2014 | |
Diabetes Mellitus, Type 2 | Liechtenstein | 16 Jan 2014 | |
Diabetes Mellitus, Type 2 | Norway | 16 Jan 2014 |
Phase 2 | 2 | (Alpelisib + Fulvestrant + Dapagliflozin + Metformin XR) | xwlhbxcove = bldmohapza rnnpkswvkc (zffdigfpcp, ghcozlrpnx - aszbwaufga) View more | - | 12 Dec 2023 | ||
(Alpelisib + Fulvestrant + Metformin XR) | kzzfkstyup = mxatmfvmip bublwwluyp (lbkyybddla, yvhfmfvpwa - ryqqvnduyn) View more | ||||||
Phase 1 | 40 | (Test Product (T)) | kzbrcmcspd(upjxinskyj) = fyvtoycvxh bvtfbgwcpc (pqjsicgtks, 25.302) View more | - | 19 Feb 2018 | ||
(Reference Product (R)) | kzbrcmcspd(upjxinskyj) = mnukfgohnb bvtfbgwcpc (pqjsicgtks, 25.135) View more |