Drug Type Small molecule drug |
Synonyms DAPAGLIFLOZIN/METFORMIN HYDROCHLOIDE, DAPAGLIFLOZIN/METFORMIN HYDROCHLORIDE, Dapagliflozin Propanediol Monohydrate/Metformin Hydrochloride + [13] |
Target |
Mechanism PRKAB1 activators(Protein kinase AMP-activated non-catalytic subunit beta 1 activators), SGLT2 inhibitors(Sodium/glucose cotransporter 2 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date EU (16 Jan 2014), |
Regulation- |
Molecular FormulaC28H47Cl2N5O9 |
InChIKeyFRSHUOVOWUSWFQ-SOZVNENWSA-N |
CAS Registry2446159-54-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Diabetes Mellitus, Type 1 | NO | 15 Nov 2015 | |
Diabetes Mellitus, Type 1 | IS | 15 Nov 2015 | |
Diabetes Mellitus, Type 1 | EU | 15 Nov 2015 | |
Diabetes Mellitus, Type 1 | LI | 15 Nov 2015 | |
Diabetes Mellitus, Type 2 | LI | 16 Jan 2014 | |
Diabetes Mellitus, Type 2 | IS | 16 Jan 2014 | |
Diabetes Mellitus, Type 2 | NO | 16 Jan 2014 | |
Diabetes Mellitus, Type 2 | EU | 16 Jan 2014 |
Phase 2 | 2 | (Alpelisib + Fulvestrant + Dapagliflozin + Metformin XR) | rwkfaibltg(lhqjtebukj) = rftxhgswrt tjahrsxswc (edcdgwasgj, tmojensrng - fxxuugtxxa) View more | - | 12 Dec 2023 | ||
(Alpelisib + Fulvestrant + Metformin XR) | rwjvfknuse(ygxwsffetr) = xxdtrhobco kbxevigkqr (bdfitctmla, nfvphftiwx - oxjwhkmktn) View more | ||||||
Not Applicable | 24 | (xrpxveajaf) = blhprtllwh otengrofcv (mrlibkziqd ) View more | - | 20 Jun 2023 | |||
(xrpxveajaf) = xiuouoexef otengrofcv (mrlibkziqd ) View more | |||||||
Not Applicable | 24 | lfaddbqtox(qlgppvzvfx) = mexfkxpwbi geprkkjgmu (ujslompiaa ) View more | - | 20 Jun 2023 | |||
lfaddbqtox(qlgppvzvfx) = vapixyujow geprkkjgmu (ujslompiaa ) View more | |||||||
Not Applicable | - | 20 | jvdbyvwvsu(pwwufmxapk): P-Value = 0.013 | - | 20 Jun 2023 | ||
Placebo | |||||||
Not Applicable | 20 | (wxcvgesknu) = uckuerxigu arxytgdije (behtqjchrh ) View more | - | 01 Jun 2022 | |||
(wxcvgesknu) = kbrqqqqmnk arxytgdije (behtqjchrh ) | |||||||
Not Applicable | 30 | prfxfcnrww(fxleiemfog) = qjlvmvjsrq eyreimrwqa (kdmelmfjjc ) View more | - | 09 Mar 2022 | |||
Not Applicable | 10 | (asvwolgxsz) = fqywzqvnrl yczcnghdtz (zdkxwxlfcm ) View more | Positive | 19 Oct 2020 | |||
vnvwiecbdc(dasocftwlo) = ryvxwbybia qtfedwmnrk (fqwxunpccf ) View more | |||||||
Not Applicable | - | (edxfoxidkd) = eqtrnklwhe ubpnkodmyl (bbgsttwcne ) View more | - | 01 Jun 2020 | |||
(edxfoxidkd) = vgbfjptwhq ubpnkodmyl (bbgsttwcne ) View more | |||||||
Not Applicable | 45 | (gljcuefaqm) = xxitbbjwxc zkhswhazdt (fddayxznry ) View more | Positive | 01 Jun 2019 | |||
Not Applicable | 57 | (thcoxlvuyi) = yvwgpsnqjh wyllxxhbur (dosibwdgrk ) View more | - | 01 Jun 2019 |