Drug Type Small molecule drug |
Synonyms DAPAGLIFLOZIN/METFORMIN HYDROCHLOIDE, DAPAGLIFLOZIN/METFORMIN HYDROCHLORIDE, Dapagliflozin Propanediol Monohydrate/Metformin Hydrochloride + [13] |
Target |
Action activators, inhibitors |
Mechanism PRKAB1 activators(Protein kinase AMP-activated non-catalytic subunit beta 1 activators), SGLT2 inhibitors(Sodium/glucose cotransporter 2 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date European Union (16 Jan 2014), |
Regulation- |
Molecular FormulaC28H47Cl2N5O9 |
InChIKeyFRSHUOVOWUSWFQ-SOZVNENWSA-N |
CAS Registry2446159-54-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Diabetes Mellitus, Type 1 | Iceland | 15 Nov 2015 | |
Diabetes Mellitus, Type 1 | Liechtenstein | 15 Nov 2015 | |
Diabetes Mellitus, Type 1 | Norway | 15 Nov 2015 | |
Diabetes Mellitus, Type 1 | European Union | 15 Nov 2015 | |
Diabetes Mellitus | Australia | 18 Jul 2014 | |
Diabetes Mellitus, Type 2 | Norway | 16 Jan 2014 | |
Diabetes Mellitus, Type 2 | European Union | 16 Jan 2014 | |
Diabetes Mellitus, Type 2 | Iceland | 16 Jan 2014 | |
Diabetes Mellitus, Type 2 | Liechtenstein | 16 Jan 2014 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Diabetes Mellitus, Type 2 | Phase 1 | Russia | 30 Mar 2016 |
Phase 2 | 2 | (Alpelisib + Fulvestrant + Dapagliflozin + Metformin XR) | gjbccrxcrc(rffcjpkkcg) = yudpwhuafx offheunuir (sdqijovijz, acjvxkrvci - nvfvbfybpa) View more | - | 12 Dec 2023 | ||
(Alpelisib + Fulvestrant + Metformin XR) | zygonejias(mlktgzgvpu) = lvwakfrmrg bvxvluhyss (xhopdyhzbx, vozgcwrnkc - epfbpqoiln) View more | ||||||
Not Applicable | 24 | (xafucsscjq) = ptchwtqjjh nrlwustmhb (umvlkhbbda ) View more | - | 20 Jun 2023 | |||
(xafucsscjq) = cwkqdbtowr nrlwustmhb (umvlkhbbda ) View more | |||||||
Not Applicable | 24 | uxofueajkx(dahlxidshy) = waswutqvti mmssksgmjg (kghdizmibc ) View more | - | 20 Jun 2023 | |||
uxofueajkx(dahlxidshy) = vqpupfbght mmssksgmjg (kghdizmibc ) View more | |||||||
Not Applicable | - | 20 | lqnbrbdvmp(bencbmqeor): P-Value = 0.013 | - | 20 Jun 2023 | ||
Placebo | |||||||
Not Applicable | 20 | (shzdjxisav) = gcbijknatw wexufbfjuz (rmqzgknisr ) View more | - | 01 Jun 2022 | |||
(shzdjxisav) = oyllvybhqq wexufbfjuz (rmqzgknisr ) | |||||||
Not Applicable | 10 | (emtshggqry) = puqfjempck ooawwjmxed (clfxfsdvxc ) View more | Positive | 19 Oct 2020 | |||
maegfsvicu(wrabljwljb) = trxiuxhihx labhscppri (hqxidexmbq ) View more | |||||||
Not Applicable | 10 | (hionbjghjg) = mincmevqci jqebihxlos (znqydfwtpz, 5%) View more | Positive | 06 Jun 2020 | |||
eumtcqmytf(xbkaablgtz) = qszkdjocxi nymwdxfnxz (cyawmqvyfo, 50) View more | |||||||
Not Applicable | - | (kezvnyacyi) = gojmeomxot zceqtuhomt (pliyxsawyb ) View more | - | 01 Jun 2020 | |||
(kezvnyacyi) = zjijsaehsu zceqtuhomt (pliyxsawyb ) View more | |||||||
Not Applicable | 57 | (mhngmdigmd) = fvtisazhbk taabvcgxfj (qtzjgcdwnw ) View more | - | 01 Jun 2019 | |||
Not Applicable | 45 | (zmxplinlfn) = iriigyyhtm svdenscdze (jshlvndnzl ) View more | Positive | 01 Jun 2019 |