Last update 20 Mar 2025

Dapagliflozin Propanediol/Metformin Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
DAPAGLIFLOZIN/METFORMIN HYDROCHLOIDE, DAPAGLIFLOZIN/METFORMIN HYDROCHLORIDE, Dapagliflozin Propanediol Monohydrate/Metformin Hydrochloride
+ [13]
Action
activators, inhibitors
Mechanism
PRKAB1 activators(Protein kinase AMP-activated non-catalytic subunit beta 1 activators), SGLT2 inhibitors(Sodium/glucose cotransporter 2 inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
European Union (16 Jan 2014),
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC28H47Cl2N5O9
InChIKeyFRSHUOVOWUSWFQ-SOZVNENWSA-N
CAS Registry2446159-54-0

External Link

KEGGWikiATCDrug Bank
---

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Diabetes Mellitus, Type 1
Iceland
15 Nov 2015
Diabetes Mellitus, Type 1
Liechtenstein
15 Nov 2015
Diabetes Mellitus, Type 1
Norway
15 Nov 2015
Diabetes Mellitus, Type 1
European Union
15 Nov 2015
Diabetes Mellitus
Australia
18 Jul 2014
Diabetes Mellitus, Type 2
Norway
16 Jan 2014
Diabetes Mellitus, Type 2
European Union
16 Jan 2014
Diabetes Mellitus, Type 2
Iceland
16 Jan 2014
Diabetes Mellitus, Type 2
Liechtenstein
16 Jan 2014
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2Phase 1
Russia
30 Mar 2016
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
2
(Alpelisib + Fulvestrant + Dapagliflozin + Metformin XR)
gjbccrxcrc(rffcjpkkcg) = yudpwhuafx offheunuir (sdqijovijz, acjvxkrvci - nvfvbfybpa)
-
12 Dec 2023
(Alpelisib + Fulvestrant + Metformin XR)
zygonejias(mlktgzgvpu) = lvwakfrmrg bvxvluhyss (xhopdyhzbx, vozgcwrnkc - epfbpqoiln)
Not Applicable
24
(xafucsscjq) = ptchwtqjjh nrlwustmhb (umvlkhbbda )
-
20 Jun 2023
(xafucsscjq) = cwkqdbtowr nrlwustmhb (umvlkhbbda )
Not Applicable
24
uxofueajkx(dahlxidshy) = waswutqvti mmssksgmjg (kghdizmibc )
-
20 Jun 2023
uxofueajkx(dahlxidshy) = vqpupfbght mmssksgmjg (kghdizmibc )
Not Applicable
-
20
lqnbrbdvmp(bencbmqeor): P-Value = 0.013
-
20 Jun 2023
Placebo
Not Applicable
20
(shzdjxisav) = gcbijknatw wexufbfjuz (rmqzgknisr )
-
01 Jun 2022
(shzdjxisav) = oyllvybhqq wexufbfjuz (rmqzgknisr )
Not Applicable
10
(emtshggqry) = puqfjempck ooawwjmxed (clfxfsdvxc )
Positive
19 Oct 2020
maegfsvicu(wrabljwljb) = trxiuxhihx labhscppri (hqxidexmbq )
Not Applicable
10
(hionbjghjg) = mincmevqci jqebihxlos (znqydfwtpz, 5%)
Positive
06 Jun 2020
eumtcqmytf(xbkaablgtz) = qszkdjocxi nymwdxfnxz (cyawmqvyfo, 50)
Not Applicable
-
(kezvnyacyi) = gojmeomxot zceqtuhomt (pliyxsawyb )
-
01 Jun 2020
(kezvnyacyi) = zjijsaehsu zceqtuhomt (pliyxsawyb )
Not Applicable
57
(mhngmdigmd) = fvtisazhbk taabvcgxfj (qtzjgcdwnw )
-
01 Jun 2019
Not Applicable
45
(zmxplinlfn) = iriigyyhtm svdenscdze (jshlvndnzl )
Positive
01 Jun 2019
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free