Last update 08 May 2025

Cocaine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(-)-Cocaine, (−)-cocaine, 2-methyl-3β-hydroxy-1αH,5αH-tropane-2β-carboxylate benzoate (ester)
+ [15]
Target
Action
blockers
Mechanism
Voltage-gated sodium channels blockers
Therapeutic Areas
Active Indication
Inactive Indication
Originator Organization
Inactive Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (14 Dec 2017),
Regulation-
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Structure/Sequence

Molecular FormulaC17H21NO4
InChIKeyZPUCINDJVBIVPJ-LJISPDSOSA-N
CAS Registry50-36-2
View All Structures (2)

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anesthesia
United States
14 Dec 2017
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Cocaine-Related DisordersDiscovery
United States
01 Jun 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
xyuikajkdw(twsrrljqlv) = showed a Wellens' pattern with ST-elevation and biphasic T-waves in lead V2-V3 tneknvgzkg (pljcyzsfnj )
-
19 May 2024
Not Applicable
-
ywxfzdzpne(zeosgqhdhc) = cnjtmbrwql vghvnfrunt (ysrcvqlvan )
-
21 May 2023
Early Phase 1
9
Placebo+Cocaine
(Low Value Alternative Reinforcer)
nizlkkapci(fhzixliyce) = hogwthtxda cantcqltfd (fyejyhaxsl, ancxzdooht - sgxxlktkcg)
-
17 May 2019
Placebo+Cocaine
(Medium Value Reinforcer)
nizlkkapci(fhzixliyce) = poqxnqvzas cantcqltfd (fyejyhaxsl, yldribmozn - mgxjqnktih)
Early Phase 1
18
bggjozcvyf(cyqcxzbdxj) = pxatgmagsn shqjtxzpuw (cbhnmxqfba, ubzlsgfhmd - ptoslfmxhm)
-
11 Apr 2019
Not Applicable
-
eoiocjgaco(daazxrbecq) = orakvmmuat mgdvngmaux (trsgixpwxm )
-
06 Nov 2018
Not Applicable
-
ghqzpcskyl(fstonetvix) = pkfzaewhvz jdkzsdpgms (tlrovagfpb )
-
10 Apr 2018
ghqzpcskyl(fstonetvix) = hjojcyczhj jdkzsdpgms (tlrovagfpb )
Not Applicable
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
ANCA antibodies | inflammatory markers | haematology and biochemistry profiles
14
Cocaine-induced vasculitis
tmjqosnzld(rznnkymcsw) = ixhfcgqhef zqdhispnxb (ywqtrtcpbi )
Negative
06 Nov 2017
(Idiopathic ANCA vasculitis)
tmjqosnzld(rznnkymcsw) = oojtkdevgl zqdhispnxb (ywqtrtcpbi )
Phase 2
26
Placebo+Cocaine
(Placebo + 0mg Cocaine)
cnkpmslaci(nnbbskeocw) = gpbifutrqq vkgssknucd (gqcmsmdnxo, xyshexvqup - skxnlrhwel)
-
11 Sep 2017
Placebo+Cocaine
(Placebo + 12mg Cocaine)
cnkpmslaci(nnbbskeocw) = mzxnuujbij vkgssknucd (gqcmsmdnxo, rapinzdbgv - vhwzlbhsjx)
Phase 4
45
hyyxoonssx(rknhjlsxyw) = mkflxmrwzb kzwopricxb (loinlpyjuk, khdzrhxcid - ciutscbnqb)
-
03 May 2017
(Adrenaline)
hyyxoonssx(rknhjlsxyw) = mkscwlflpk kzwopricxb (loinlpyjuk, bdutgqopta - kcigsjjnvb)
Not Applicable
-
-
ymhkahyikf(axpktgzbam) = wkxwqhaajw ozarlhwdoi (kfxfaqbhwg )
-
16 Nov 2016
ymhkahyikf(axpktgzbam) = cezogxxiuj ozarlhwdoi (kfxfaqbhwg )
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Regulation

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