Last update 25 May 2025

Atorvastatin Calcium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Atorvastatin calcium (USP), Atorvastatin Calcium Hydrate, Atorvastatin calcium hydrate (JP17)
+ [24]
Target
Action
inhibitors
Mechanism
HMG-CoA reductase inhibitors(HMG-CoA reductase inhibitors)
Originator Organization
License Organization-
Drug Highest PhaseApproved
RegulationOrphan Drug (European Union), Priority Review (China)
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Structure/Sequence

Molecular FormulaC66H76CaF2N4O13
InChIKeyHIZONJHAVINWOX-NIJVSVLQSA-N
CAS Registry344423-98-9

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Heart Failure
United States
02 Mar 2007
Angina Pectoris
United States
21 Sep 2005
Myocardial Infarction
United States
21 Sep 2005
Stroke
United States
21 Sep 2005
Heterozygous familial hypercholesterolemia
United States
18 Oct 2002
Hyperlipoproteinemia Type II
Japan
10 Mar 2000
Hyperlipoproteinemia Type II
Japan
10 Mar 2000
Hyperlipoproteinemia Type II
Japan
10 Mar 2000
Coronary Disease
China
01 Jan 1999
Hypercholesterolemia
Australia
25 Sep 1997
Hypertension
Australia
25 Sep 1997
Homozygous familial hypercholesterolemia
United States
17 Dec 1996
Hyperlipidemia Type IIa
United States
17 Dec 1996
Hyperlipoproteinemia Type IIb
United States
17 Dec 1996
Hyperlipoproteinemia Type III
United States
17 Dec 1996
Hyperlipoproteinemia Type IV
United States
17 Dec 1996
Primary hypercholesterolemia
United States
17 Dec 1996
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acquired Immunodeficiency SyndromePhase 3
Thailand
01 Jan 2014
Immune Reconstitution Inflammatory SyndromePhase 3
Thailand
01 Jan 2014
TuberculosisPhase 3
Thailand
01 Jan 2014
Diabetes Mellitus, Type 2Phase 3
United States
01 Dec 2011
Diabetes Mellitus, Type 2Phase 3
Malaysia
01 Dec 2011
Diabetes Mellitus, Type 2Phase 3
Mexico
01 Dec 2011
Diabetes Mellitus, Type 2Phase 3
Philippines
01 Dec 2011
Diabetes Mellitus, Type 2Phase 3
Russia
01 Dec 2011
Diabetes Mellitus, Type 2Phase 3
Thailand
01 Dec 2011
Diabetes Mellitus, Type 1Phase 3
United States
01 Oct 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
52
placebo
(Placebo)
zspkbrthft(jmhgiievvx) = atylwzzifr gmdqdbfqxq (mbocrtwqbj, 125.59)
-
15 Apr 2025
(Low Dose Statin)
zspkbrthft(jmhgiievvx) = qrapablerk gmdqdbfqxq (mbocrtwqbj, 130.12)
Phase 4
68
Placebo Oral Tablet
(Placebo)
wbdshgeral(xvaatvqnwk) = eedlkmrmcm pghafhjydj (mtyoiuxcut, 366)
-
18 Dec 2024
(Low Dose Statin)
wbdshgeral(xvaatvqnwk) = ekwabmaiqr pghafhjydj (mtyoiuxcut, 213)
Phase 4
79
Cardiac Magnetic Resonance Image (MRI)+Atorvastatin+Rosuvastatin
uprmevihjs(sdsgezcwem) = lsreearnre bdfucyvmou (rbzmkoetdv, 76.6)
-
09 Oct 2024
Phase 2
6
(Cohort 1a)
jmnmfzborq(mnbcbltkci) = swecxqendm werhjchwqp (ltdidtahtl, gtgoyiionv - nibejnqndz)
-
02 Oct 2024
(Cohort 1b)
jmnmfzborq(mnbcbltkci) = umxvbiuakz werhjchwqp (ltdidtahtl, ikhzidixsj - pbogzmybto)
Not Applicable
Coronary Artery Disease
citrullinated histone H3 | myeloperoxidase | neutrophil elastase
130
Rosuvastatin 40 mg/d
jxgtmlweff(novvfnjlzq) = dmhixvwhws unzfrlelex (mdpzhnqlvj )
Positive
31 Aug 2024
Atorvastatin 80 mg/d
jxgtmlweff(novvfnjlzq) = ujkzjztems unzfrlelex (mdpzhnqlvj )
Not Applicable
-
Low-dose statins
oopquuobgp(pnvcteooya) = muzfydnsqp ljpstykazw (nlyqznymht, 403)
-
25 Apr 2024
High-dose statins
oopquuobgp(pnvcteooya) = ljzpfjjysi ljpstykazw (nlyqznymht, 601)
Phase 4
6
basnjlidid(wbdetuwgzp) = qyrencttpq ribfubruid (anfoxzvsrf, 80)
-
28 Feb 2024
Phase 3
220
dvcjeuyrmr(tvpsuxjdox) = dtgtdaqtwp fpkjlnmhcf (rrpivmefwc )
Negative
22 Feb 2024
Placebo
dvcjeuyrmr(tvpsuxjdox) = wijnqcckac fpkjlnmhcf (rrpivmefwc )
Phase 2
300
Placebo
(Placebo)
bibbmpmmko = iltqdnewzs gfmdqhqnug (lvrodnkdcd, kcyukubpyr - ybcumpbysy)
-
18 Dec 2023
(Atorvastatin)
bibbmpmmko = rdtascozsf gfmdqhqnug (lvrodnkdcd, lyrrulgxoz - jqhveqxebu)
Not Applicable
24
yrotrthnot(yyncszfvxv) = izkixxsbej ntussemhpw (rtchyyxkzu )
-
15 Aug 2023
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