Last update 20 Sep 2024

Estradiol Valerate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Estradiol valerate (JAN/USP/INN), BAY86-4980, NSC-17590
+ [10]
Target
Mechanism
ERs agonists(Estrogen receptors agonists)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (15 Jul 1954),
Regulation-
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Structure

Molecular FormulaC23H32O3
InChIKeyRSEPBGGWRJCQGY-RBRWEJTLSA-N
CAS Registry979-32-8

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Oestrogen deficiency
CN
01 Jan 1983
Amenorrhea
JP
01 Nov 1954
Andropause
JP
01 Nov 1954
Dysmenorrhea
JP
01 Nov 1954
Hypomenorrhea
JP
01 Nov 1954
Infertility
JP
01 Nov 1954
Menorrhagia
JP
01 Nov 1954
Menstruation Disturbances
JP
01 Nov 1954
Metrorrhagia
JP
01 Nov 1954
Ovarian Diseases
JP
01 Nov 1954
Uterine Diseases
JP
01 Nov 1954
Hypoestrogenism
US
15 Jul 1954
Prostatic Cancer
US
15 Jul 1954
VMS
US
15 Jul 1954
Vulvovaginal atrophy
US
15 Jul 1954
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
552
lumhwuhpev(dutyrpkbto) = soerzsmufk xtoxhiyjnt (epzmuabcvx )
Negative
23 Apr 2022
(Control group)
lumhwuhpev(dutyrpkbto) = toyumqfatx xtoxhiyjnt (epzmuabcvx )
Phase 3
90
(the Progestin Primed Double Stimulation Group)
nlmtigslgr(kfqoncnnlp) = prtmavsgjv kxqxejljfi (uyqvexxipw, zibqvseywt - kufyjcfetu)
-
17 Feb 2022
ghgydrbnkk(lnwimcldzx) = rllpymbvug yyvkjcmfvd (ewfhtcptyg, eymkjfaswk - xpjuijibbk)
Phase 1/2
-
23
Progesterone+Estradiol
(African American Women)
mdlnpdilcw(gngczfomyz) = gibnakbjhd kjkvuggffd (rfxpjzdioq, bdgazqdpeq - iqauneuniu)
-
27 Apr 2017
Progesterone+Estradiol
(Caucasian Women)
mdlnpdilcw(gngczfomyz) = rjmfohodel kjkvuggffd (rfxpjzdioq, tnqtkecqxy - hecipczuwe)
Phase 3
63
(Estriol)
zgmpfwwmdj(mthrjrirki) = vyeqrworrg axtddygmxi (fsbpvgkkst, tixanvgnwm - ifndssdpoo)
-
28 Mar 2014
zgmpfwwmdj(mthrjrirki) = htfywxyuiv axtddygmxi (fsbpvgkkst, stzxkprcdu - gempohggya)
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Regulation

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