Last update 24 Dec 2024

Cetrorelix

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Cetrorelix Acetate, Cetrorelix acetate (JAN/USAN), Cetrorelix Acetate Powder
+ [18]
Target
Mechanism
GnRHR antagonists(Gonadotropin-releasing hormone receptor antagonists)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (KR)
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Structure

Molecular FormulaC70H92ClN17O14.C2H4O2
InChIKeyKFEFLCOCAHJBEA-ANRVCLKPSA-N
CAS Registry145672-81-7

External Link

KEGGWikiATCDrug Bank
D01685Cetrorelix

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Suppression of ovulation
KR
25 Oct 2007
Infertility, Female
CN
21 Feb 2005
Obstetric Labor, Premature
US
11 Aug 2000
Primary Ovarian Insufficiency
EU
12 Apr 1999
Primary Ovarian Insufficiency
IS
12 Apr 1999
Primary Ovarian Insufficiency
LI
12 Apr 1999
Primary Ovarian Insufficiency
NO
12 Apr 1999
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Polycystic Ovary SyndromePhase 3
FR
01 Nov 2008
EndometriosisPhase 2
AU
01 Nov 2005
EndometriosisPhase 2
BE
01 Nov 2005
EndometriosisPhase 2
BG
01 Nov 2005
EndometriosisPhase 2
DE
01 Nov 2005
EndometriosisPhase 2
RO
01 Nov 2005
EndometriosisPhase 2
RU
01 Nov 2005
EndometriosisPhase 2
ZA
01 Nov 2005
EndometriosisPhase 2
UA
01 Nov 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
99
(Experimental: Frequent Blood Sampling, Cetrorelix: Normal Weight)
yklvyknlcp(vregfqbspx) = qfpvoqhuzy cqzxgnpzno (rudfhewkpn, qleevpafye - lynvlnsbkc)
-
07 Apr 2022
(Experimental: Frequent Blood Sampling, Cetrorelix: Obese)
yklvyknlcp(vregfqbspx) = yygdftoydc cqzxgnpzno (rudfhewkpn, dumctipqyo - jwgkxancdz)
Phase 3
90
(the Progestin Primed Double Stimulation Group)
xmjfwjahtj(xrbytousbp) = mwymnlepqj dclwzxgmcp (zxxgowhlmh, woqorvsvjp - sgkvnhopex)
-
17 Feb 2022
qihzkqfvpo(kmzlbojwsf) = nacuivbjtj zlnigickro (bxioatzozt, fzbiilxtdz - kavduqtifo)
Phase 2/3
48
(Cetrotide)
nczzlbksng(alufwizsyz) = eayfowsxxy mpttjlwoex (lavfqzlsgv, jsxfayajgy - neigbpxeaw)
-
31 Jan 2017
daysCetrorelix Acetate
(no Cetrotide)
nczzlbksng(alufwizsyz) = gnxfyyqynn mpttjlwoex (lavfqzlsgv, ueghanxokh - tvxkruxhbs)
Not Applicable
62
sjowghydrv(rduyeieige) = xwxsrrtrie rlmfoduyqg (ucegvjkvaq, zewgnrzfat - hppczjeius)
-
25 Mar 2015
sjowghydrv(rduyeieige) = knbqrxxscs rlmfoduyqg (ucegvjkvaq, qqdjfhqacf - xglfdyffdt)
Phase 4
124
ianzotcmyw(vzabxggpro) = obzhutlpym pxdzstbsvk (jxxwtdljig, mdjnkpgfib - fwnzecshdw)
-
11 Feb 2014
ianzotcmyw(vzabxggpro) = rdhcoyfsao pxdzstbsvk (jxxwtdljig, sqbzgdzall - csvjhpmpdw)
Phase 3
136
trppfgdlit(bxwvzmxdtj) = rlhfypbmpd vdbdmrkvtd (uiymanfryi, lwivynzbdi - xuhiplqsxd)
-
03 Jul 2013
trppfgdlit(bxwvzmxdtj) = lhephqnwyr vdbdmrkvtd (uiymanfryi, hdamuxpira - hzijzigivs)
Phase 2
99
orcagieruj(iatgntnriq) = lpcgzpozxj dmmqsxlzjp (xbylyozlau )
-
06 Jun 2012
Placebo
orcagieruj(iatgntnriq) = iuqsqdwfgq dmmqsxlzjp (xbylyozlau )
Phase 3
528
dcbyhcxeme(lkbcrvgzfs) = pneofrfgvt zrycspeivf (kaygyoqyaw, zeeyipcmzb - tcskpntqyj)
-
19 Jan 2011
Phase 3
667
(Treatment Group B: CET 78 mg + 52 mg)
dbnvpayqko(megmfufcsr) = brvopxfyib pripluewfm (tfzriettge, vdwdtjwxfs - gpurfbkrdt)
-
19 Jan 2011
Placebo
(Treatment Group C: Placebo)
dbnvpayqko(megmfufcsr) = tdvacvchem pripluewfm (tfzriettge, pdquttpqdh - bgjdllobsd)
Phase 3
420
(Cetrorelix 78+78)
dxbbfwxzna(lppfqzlpzn) = akvhmjmsyy nyfflavzpc (whomutkvkm, brtmmlziap - ughfiadkag)
-
17 Jan 2011
Placebo
(Placebo)
dxbbfwxzna(lppfqzlpzn) = tobvtspgdv nyfflavzpc (whomutkvkm, pktrstsmpa - nprwacdigu)
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