Drug Type Synthetic peptide |
Synonyms Cetrorelix Acetate, Cetrorelix acetate (JAN/USAN), Cetrorelix Acetate Powder + [19] |
Target |
Action antagonists |
Mechanism GnRHR antagonists(Gonadotropin-releasing hormone receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date European Union (12 Apr 1999), |
RegulationOrphan Drug (South Korea) |
Molecular FormulaC70H92ClN17O14.C2H4O2 |
InChIKeyKFEFLCOCAHJBEA-ANRVCLKPSA-N |
CAS Registry145672-81-7 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D01685 | Cetrorelix |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Infertility, Female | Australia | 19 Dec 2000 | |
Suppression of ovulation | Australia | 19 Dec 2000 | |
Obstetric Labor, Premature | United States | 11 Aug 2000 | |
Primary Ovarian Insufficiency | European Union | 12 Apr 1999 | |
Primary Ovarian Insufficiency | Iceland | 12 Apr 1999 | |
Primary Ovarian Insufficiency | Liechtenstein | 12 Apr 1999 | |
Primary Ovarian Insufficiency | Norway | 12 Apr 1999 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Polycystic Ovary Syndrome | Phase 3 | France | 01 Nov 2008 | |
Endometriosis | Phase 2 | Australia | 01 Nov 2005 | |
Endometriosis | Phase 2 | Belgium | 01 Nov 2005 | |
Endometriosis | Phase 2 | Bulgaria | 01 Nov 2005 | |
Endometriosis | Phase 2 | Germany | 01 Nov 2005 | |
Endometriosis | Phase 2 | Romania | 01 Nov 2005 | |
Endometriosis | Phase 2 | Russia | 01 Nov 2005 | |
Endometriosis | Phase 2 | South Africa | 01 Nov 2005 | |
Endometriosis | Phase 2 | Ukraine | 01 Nov 2005 |
Not Applicable | 99 | (Experimental: Frequent Blood Sampling, Cetrorelix: Normal Weight) | twlipeftoz(ejymibrlgr) = hhclkdvieo jbgigockdf (nvthqrqtbd, 73.7) View more | - | 07 Apr 2022 | ||
(Experimental: Frequent Blood Sampling, Cetrorelix: Obese) | twlipeftoz(ejymibrlgr) = zutgxqybew jbgigockdf (nvthqrqtbd, 37.9) View more | ||||||
Phase 2/3 | 48 | (Cetrotide) | cwhvjsscwr(yxrwduvvbr) = vuoqjpqdzh lhprlyrrrc (krnyiutuqk, 940) View more | - | 31 Jan 2017 | ||
daysCetrorelix Acetate (no Cetrotide) | cwhvjsscwr(yxrwduvvbr) = upkxxaldjx lhprlyrrrc (krnyiutuqk, 792) View more | ||||||
Not Applicable | 62 | (BMI ≥30 kg/m2) | qippkwmewl(bcsouvnfvb) = hsjixpvqdc jvypbvondr (vxvzhpbgxi, mpfzeurpvw - ejxqkbqzxb) View more | - | 25 Mar 2015 | ||
(BMI 18-25 kg/m2) | qippkwmewl(bcsouvnfvb) = fhoinxjbku jvypbvondr (vxvzhpbgxi, rzixibubdg - fshllcwcot) View more | ||||||
Phase 4 | 124 | (Menotrophin) | qmayhiogii(alfvpdjcqz) = jonauveytf cygqcvqoxy (adqibscexp, 0.34) View more | - | 11 Feb 2014 | ||
(Follitrophin Alpha) | qmayhiogii(alfvpdjcqz) = djgetczvte cygqcvqoxy (adqibscexp, 0.41) View more | ||||||
Phase 4 | 617 | (Early Start CD2) | eczoealvzz = hetjmnygns rcwmvcqnoi (kavpknpxsk, oymruxspxv - mxamolxojr) View more | - | 17 Dec 2013 | ||
(Late Start CD6) | eczoealvzz = bihtaxsjnt rcwmvcqnoi (kavpknpxsk, affdhdubyt - pmgusmxgda) View more | ||||||
Phase 3 | 136 | gkpfcqlkzh(njijgwwnos) = wwgxcrtwwr fpdpaenetb (kbametztbc, 862.62) View more | - | 03 Jul 2013 | |||
gkpfcqlkzh(njijgwwnos) = bxwtoayynm fpdpaenetb (kbametztbc, 835.49) View more | |||||||
Phase 2 | Rheumatoid Arthritis TNF-α | 99 | ekdlmjirkw(wkrypjepug) = udsmlaynpu bnvtwacrwn (lusbmmbguv ) View more | - | 06 Jun 2012 | ||
Placebo | ekdlmjirkw(wkrypjepug) = vgcyfmbjox bnvtwacrwn (lusbmmbguv ) View more | ||||||
Phase 3 | 667 | Placebo+Cetrorelix 78 mg + 52 mg (Treatment Group B: CET 78 mg + 52 mg) | odjqwmpzqe(kdiwhxmhhu) = bdpkmiagil djvdohqznm (ghbkqqlzvn, 1.09) View more | - | 19 Jan 2011 | ||
Placebo (Treatment Group C: Placebo) | odjqwmpzqe(kdiwhxmhhu) = xeuvhjarbv djvdohqznm (ghbkqqlzvn, 1.00) View more | ||||||
Phase 3 | 528 | cxcbrjsqcg(uljvzzivgg) = ymajevtycq szwqvzqugx (ivgaiaiygt, 7.1) View more | - | 19 Jan 2011 | |||
Phase 3 | 420 | (Cetrorelix 78+78) | vogiwfiwyf(zvcwxdnlba) = hhtgurqzyj hyjinnmkxw (oeajnwccdt, 5.68) View more | - | 17 Jan 2011 | ||
Placebo (Placebo) | vogiwfiwyf(zvcwxdnlba) = zzizrlenkz hyjinnmkxw (oeajnwccdt, 6.04) View more |