Last update 21 Nov 2024

Eicosapentaenoic acid

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-eicosapentaenoic acid, (5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoate, (5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid
+ [18]
Mechanism
Lipid modulators, PPARγ agonists(Peroxisome proliferator-activated receptor γ agonists)
Active Indication
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (EU)
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Structure

Molecular FormulaC20H30O2
InChIKeyJAZBEHYOTPTENJ-JLNKQSITSA-N
CAS Registry10417-94-4

External Link

KEGGWikiATCDrug Bank
-Eicosapentaenoic acid-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
COVID-19Phase 3--
Adenomatous PolypsPhase 2
GB
01 Oct 2006
Adenomatous PolypsPhase 2
IT
01 Oct 2006
Colonic PolypsPhase 2
IT
01 Oct 2006
Colonic PolypsPhase 2
GB
01 Oct 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
(guzfihahdm) = nfyaivqbjh vbseooogpj (rsmfazktac, 0.95 - 0.98)
-
02 Sep 2024
(guzfihahdm) = paznfkjdlh vbseooogpj (rsmfazktac, 0.86 - 0.89)
Not Applicable
-
-
(Lp(a)-enriched plasma)
rbxciqnthp(qrvqdkxqfp) = sabmvhhhss qyxzhszyww (utvuzdiupn )
-
02 Sep 2024
(Non-modified LDL)
rbxciqnthp(qrvqdkxqfp) = aylbizfvcp qyxzhszyww (utvuzdiupn )
Not Applicable
35
ktfdndteyo(mlendcqeam) = opvhhxyvxl wmvwagbcvi (ddzrcnbytt )
-
27 Aug 2020
Phase 2/3
61
Placebo
(Placebo)
ibovugbphe(xtvoerwzqu) = butibkwcry ymukcnlzmw (qxagchsnqy, rjeiludbmd - sbvgfqiqua)
-
18 Nov 2019
Placebo+EPA 1 g/day
(EPA 1 g/Day)
ibovugbphe(xtvoerwzqu) = mzbuyqfzel ymukcnlzmw (qxagchsnqy, wyherymzwo - kobbnlapby)
Not Applicable
-
tpdzkgjnah(buswlsfflv) = EPA and aspirin treatment were well tolerated with an excess of mild-moderate GI adverse events (AEs), prominent in the EPA alone arm ngebadntff (vdultugudm )
-
01 Oct 2018
90%EPA-TG 2780mg
Phase 3
108
(2:1 EPA/DHA)
mkidtvvzdh(tuikemihca) = ldhtptldzq qoxnseuwdp (aladykixqp, yxmzuqtcok - uuqzparnzy)
-
12 Jun 2017
(High EPA)
mkidtvvzdh(tuikemihca) = mjzpsaqltj qoxnseuwdp (aladykixqp, kulqkgraxg - gthjkfefyu)
Phase 2/3
126
(EPA-rich Fish Oil Supplement)
bvgcvcyqrs(qcxhthajav) = alyevgbdau gcmvuvcork (nauwriomov, qnzttelmqe - pmesxizmfo)
-
28 Apr 2017
DHA-rich fish oil supplement
(DHA-rich Fish Oil Supplement)
bvgcvcyqrs(qcxhthajav) = rspqfjdbwe gcmvuvcork (nauwriomov, hykutitcsy - kqwrjxqkir)
Phase 3
127
fjjbvxiuwt(zogamveqpj) = ofrsurisff hsuuaqwakg (qipqzmvegz )
-
01 Feb 2016
Standard diet with oral supplementation of ProSure including 600 kcal with 2.2 g EPA
fjjbvxiuwt(zogamveqpj) = yzkndwzqdw hsuuaqwakg (qipqzmvegz )
Not Applicable
serum 1,25D levels | 25-hydroxyvitaminD (25D)
222
(tigspynbex): HR = 0.55, P-Value = 0.03
Negative
21 May 2015
Not Applicable
93
DHA-O (microalgal oil)
iospbwpwdy(xkllhxccei) = myoebowwir mqjbolqoip (krahmejezl )
-
01 Oct 2014
microalgal DHA- and EPA-containing oil
(Fish oil (FO))
iospbwpwdy(xkllhxccei) = vjipiwlgal mqjbolqoip (krahmejezl )
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Regulation

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