Delving into the Latest Updates on Calcium Acetate with Synapse

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms

Acetate of lime, Brown acetate of lime, Calcium Acetate Granules

+ [13]

Target

Phosphates

Action

modulators

Mechanism

Phosphates modulators(Phosphates modulators)

Therapeutic Areas

Endocrinology and Metabolic DiseaseUrogenital Diseases

Active Indication-

Inactive Indication

HyperphosphatemiaKidney Failure, Chronic

Originator Organization

Fresenius Kabi AG

Active Organization-

Inactive Organization

Fresenius Medical Care North America Holdings LP

Drug Highest PhaseApproved

First Approval Date

United States (10 Dec 1990),

Hyperphosphatemia

RegulationOrphan Drug (United States)

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Structure/Sequence

Molecular FormulaC4H8CaO4

InChIKeyWGTHSEQMDUDZLL-UHFFFAOYSA-N

CAS Registry62-54-4

View All Structures (2)

[Translation] A single-center, randomized, open-label, three-period crossover phase I clinical study to evaluate the effects of calcium-containing phosphate binder calcium acetate tablets and non-calcium-containing phosphate binder sevelamer carbonate tablets on the pharmacokinetics of dedostat tablets in healthy subjects

主要目的：评估磷结合剂碳酸司维拉姆片和醋酸钙片对德度司他片药动学的影响。次要目的：观察受试者给予磷结合剂碳酸司维拉姆片和醋酸钙片与德度司他片的安全性。

[Translation]

Primary objective: To evaluate the effect of phosphate binders sevelamer carbonate tablets and calcium acetate tablets on the pharmacokinetics of depo-depo-depo-depo-depo-depo-depo-depo-depo-depo-de- ...

Start Date13 Jul 2023

Sponsor / Collaborator

Yiqiao Hunan Pharmaceuticals Co. Ltd.

ChiCTR2300072509

/ SuspendedPhase 1IIT

A Single-site, Randomized, Open-label, Three-cycle-crossover Phase I Clinical Study to Evaluate the Pharmacokinetics of the Calcium-containing Phosphate Binder Calcium Acetate Tablets and the Non-calcium-containing Phosphate Binder Sevelamer Carbonate Tablets on Desidustat Tablets in Healthy Subjects

Start Date03 Jul 2023

Sponsor / Collaborator-

100 Clinical Results associated with Calcium Acetate

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100 Translational Medicine associated with Calcium Acetate

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100 Patents (Medical) associated with Calcium Acetate

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226,222

Literatures (Medical) associated with Calcium Acetate

31 Dec 2025·Energy Sources, Part A: Recovery, Utilization, and Environmental Effects

Simultaneous improvement in qualities of bio-oil and syngas from catalytic pyrolysis of rice husk by demineralization

Author: Wang, Zhongwen ; Xiong, Yuanquan

This study aims to investigate the influences of different demineralization pretreatment processes on the properties of liquid and gas products from catalytic pyrolysis via activated carbon catalyst.To achieve this goal, deionized water, hydrochloric acid, and acetic acid were used to remove ash.The results indicated that leaching could remove a large amount of alkali and alk. earth metals (AAEMs).Besides, the experiments of different leaching solutions on catalytic fast pyrolysis of rice husks were conducted.It can be found that compared with direct pyrolysis, the catalytic pyrolysis produced more gas products, in which CO increased by 6.49%, while the bio-oil was concentrated in phenols (more than 90%).After demineralization, the content of CO in gas products further increased by 8.04%, while the relative content of phenol in bio-oil enhanced by 14.79% as well.Catalysis can enrich phenol in bio-oil, and leaching can enhance this enrichment.Meanwhile, demineralization can further improve the quality of syngas.The sample after demineralization by hydrochloric acid performed best on catalytic fast pyrolysis, where CO accounts for 57.68% volume of gaseous product and phenol accounted for 68.21% of bio-oil.

31 Dec 2025·Italian Journal of Animal Science

Dose-dependent effects of dietary sunflower meal in diets supplemented with commercial enzymes on aged laying hens

Author: Cufadar, Yusuf ; Mızrak, Cengizhan ; Golzar Adabi, Shahram ; Gül, Esra Tuğçe

The inclusion of dietary SFM at levels up to 18% in aged laying hens, in conjunction with enzyme supplementation, did not result in any detrimental or adverse effects on egg production or egg quality parameters.This dietary approach resulted in improvements in the histomorphol. of the jejunum and the composition of the caecal microbiota.A notable improvement was observed in tibia phosphorus and ileal digestibility of CP and phosphorus.

01 Jul 2025·Separation and Purification Technology

3D crosslinked chitosan for fluoride remediation in industrial wastewater: From structure to performance enhancement

Author: Wang, Qin ; Liu, Fengzhen ; Hao, Hongxun ; Li, Yan ; Zhou, Zijian ; Wang, Ting ; Wang, Na ; Huang, Xin

The development of novel adsorbent materials represents a promising approach for the remediation of fluorine pollution and the promotion of a sustainable water cycle.Nevertheless, the complex preparation processes, stringent application conditions, and limited reusability significantly impede the practical implementation of various adsorption materials.Herein, three-dimensional crosslinked chitosan (3D CS) was developed for treating wastewater containing high concentration of fluoride (hundreds and thousands of mg/L).FTIR, FE-SEM and other techniques were used to investigate several key process factors on the structure and performance of 3D CS and the optimal synthesis conditions, including chitosan hydrogel concentration (5%wt), the amount of crosslinking agent (2.5%volume/volume), acetic acid concentration (2%), drying method (353 K blast drying for 9 h), were determinedAfterwards, the optimized 3D CS demonstrates microporous structure and exceptional fluorine removal capabilities, characterized by a 6-fold enhancement in adsorption capacity (64.7 mg/g), a 5-fold improvement in recycling capacity (more than 17 times), as well as broad pH applicability range (3-12) and high salt tolerance (25000 mg/L NaCl and 5000 mg/L Na₂SO₄).Furthermore, its straightforward and low-carbon synthesis method, customizable macro shape, and ease of separation from wastewater endow the 3D CS with significant potential for practical applications.Ultimately, the adsorption mechanism was investigated and the results show that ion exchange, electrostatic attraction, and hydrogen bonding between 3D CS and HF together determine the good adsorption performance of F^-.

100 Deals associated with Calcium Acetate

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External Link

KEGG	Wiki	ATC	Drug Bank
D00931	Calcium Acetate	V03AE07	DB00258

R&D Status

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Clinical Result

Indication

Phase

Evaluation

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Study	Phase	Population	Analyzed Enrollment	Group	Results	Evaluation	Publication Date


NCT04485039 (CTgov)	Phase 4	Smallpox	44	Tecovirimat (TPOXX: Oral Antiviral)	(pbhknzyuuo) = bqzenrzfyl kzjtvapgvu (ndmcwmqbcy, emqabkqqra - zwiorvwdca) View more	-	09 Oct 2024
				Tecovirimat+sevelamer carbonate oral tablet (TPOXX: Oral Antiviral and Sevelamer Carbonate)	zmmqdghalt(hgdxvcknhm) = rgolbsqdsv ueyjgmqrae (xkppwspobe, qqxnhrjbyb - zigmndtzmf) View more
ASN2021	Not Applicable	Chronic Kidney Diseases	-	Calcium acetate	vrwwvcgdoj(fvkmwjuhea) = kkoukxprwi yzuaudvoot (jcmvwfbset )	-	27 Oct 2021
				Ferric citrate	vrwwvcgdoj(fvkmwjuhea) = fghabmnkww yzuaudvoot (jcmvwfbset )
ASN2020	Not Applicable	-	2,018	Sucroferric Oxyhydroxide (SO)	vkbiaxotnc(ovnpvvlkev) = mpavawfbtz pvxrbdkchp (ypyhqbrhae ) View more	Positive	19 Oct 2020
				Calcium Acetate	vkbiaxotnc(ovnpvvlkev) = qzhrebimlx pvxrbdkchp (ypyhqbrhae ) View more
ASN2016	Not Applicable	Hyperphosphatemia	4,674	Sevelamer	(iglqublysy): HR = 0.64 (95% CI, 0.45 - 0.91), P-Value = 0.012	Positive	15 Nov 2016
				Calcium Acetate
ASN2016	Not Applicable	-	139	Calcium Acetate	wojooftdjg(ukqobkpejg) = xfrimniast btlrcacvym (gfvmkufxxd )	Positive	15 Nov 2016
				Sucroferric Oxyhydroxide	wojooftdjg(ukqobkpejg) = xbzqkmnsgq btlrcacvym (gfvmkufxxd )
ASN2015	Not Applicable	-	-	Calcium acetate	uquxixupyy(ayauqefcbm) = gofcutzfhd fendfnpwso (qyzcfnkhwz ) View more	Positive	03 Nov 2015
				Calcium carbonate	uquxixupyy(ayauqefcbm) = ifzhetkrig fendfnpwso (qyzcfnkhwz ) View more
VIKI Study (ASN2013)	Not Applicable	Chronic Kidney Diseases BGP \| MGP	387	Calcimimetics	vxrakneiip(niblmjatxa) = gihlgxvqvu mzfwgrzmcn (eognvrijah )	Positive	05 Nov 2013
				Vitamin D analogs	vxrakneiip(niblmjatxa) = ceeseymquf mzfwgrzmcn (eognvrijah ) View more
ASN2013	Not Applicable	Kidney Failure, Chronic serum Ca \| PO4 \| ALP ... View more	150	Calcium Acetate	dciqgrkzlh(rgsluiswwo) = edsmyubtoz azevxicati (oxurwcyygg ) View more	Positive	05 Nov 2013
				Sevelamer Carbonate	dciqgrkzlh(rgsluiswwo) = oygtwsxwle azevxicati (oxurwcyygg ) View more
NCT01135615 (Pubmed \| Am J Kidney Dis)	Phase 4	Chronic Kidney Diseases	100	Sevelamer	dplhmydqzk(iredmxtljf) = gootcfywvq nbvfthsiqo (mmsjgaqjli )	-	01 Feb 2012
				Calcium Acetate	dplhmydqzk(iredmxtljf) = krpaxztfdk nbvfthsiqo (mmsjgaqjli )
NCT00211978 (Pubmed)	Phase 3	Chronic Kidney Diseases	110	Calcium acetate	(umjtbwtxte) = ohfsbycdgr xdkkqqgmdt (mbfdhxrxin )	Positive	16 Feb 2011
				Placebo	(umjtbwtxte) = zseetpndbf xdkkqqgmdt (mbfdhxrxin )