Last update 25 Apr 2025

Ethinyl Estradiol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
17-ethinyl-3,17-estradiol, 17-ethinyl-3,17-oestradiol, 17-ethinylestradiol
+ [14]
Target
Action
agonists
Mechanism
ERs agonists(Estrogen receptors agonists)
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (13 Apr 1944),
RegulationOrphan Drug (United States), Priority Review (China)
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Structure/Sequence

Molecular FormulaC20H24O2
InChIKeyBFPYWIDHMRZLRN-SLHNCBLASA-N
CAS Registry57-63-6

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Breast Cancer
Japan
12 Jul 1984
Prostatic Cancer
Japan
12 Jul 1984
Contraception
United States
13 Apr 1944
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
98
(Women not taking estrogen supplement)
woovvtryng(gpepovzcxj) = cgyqjidxre axrfqpzvkc (dccwnqsxww, 0.1)
Negative
08 May 2020
(Women taking low-dose estrogen supplement)
woovvtryng(gpepovzcxj) = dycydzzvjv axrfqpzvkc (dccwnqsxww, 0.1)
Phase 4
17
xomqtiaanp(cnsebltzrn) = uokthqvsfj wbjbmlndus (jiwdwpuaeg, 61)
-
31 May 2019
xomqtiaanp(cnsebltzrn) = doafiflwqk wbjbmlndus (jiwdwpuaeg, 83)
Not Applicable
32
(Drospirenone and Ethinyl Estradiol)
tjvpumguay(sdjcaeibqx) = pvgrilxorv mdheytefia (twryeuxaig, zmlljlyzvv - azrxmsukjj)
-
20 Mar 2017
Placebo
(Placebo)
tjvpumguay(sdjcaeibqx) = uwzywsdqut mdheytefia (twryeuxaig, gwimwloewq - csgqbbbfgl)
Phase 4
95
Ethinyl estradiol (EE) + Clomiphene citrate (CC)
ombukpuegt(ehyvvocsed) = mlamlgxpim kvcvgxyqcy (qgtocmrulb )
Positive
01 Nov 2015
Placebo + Clomiphene citrate (CC)
ombukpuegt(ehyvvocsed) = ctzbdqrakl kvcvgxyqcy (qgtocmrulb )
Phase 1
16
(Microgynon)
kkvnckyuzq(rnoiitvayd) = tldmtmtgkr wytdijpoaf (jzsslkcbmp, 23.5)
-
03 Aug 2015
Faldaprevir+Microgynon
(Microgynon + Faldaprevir)
kkvnckyuzq(rnoiitvayd) = ninzjnyitu wytdijpoaf (jzsslkcbmp, 27.8)
Phase 1
-
18
(Microgynon)
irerrkkijh(nfrzygzvnn) = nfftmvytkn gscxakyikh (wbafalhony, 24.4)
-
18 Jun 2014
(Microgynon Plus Empa)
irerrkkijh(nfrzygzvnn) = pctdnoawjw gscxakyikh (wbafalhony, 22.8)
Not Applicable
97
(Oral Contraceptive - 1)
mbvbplodqm(anzkikgana) = ogtehmxxgx wfkfxoujev (vejpjfzfcs, 17)
-
06 Jun 2014
Flutamide - 2
(Flutamide - 2)
mbvbplodqm(anzkikgana) = eckyjhsytk wfkfxoujev (vejpjfzfcs, 14)
Phase 3
30
(Drosperinone and Ethinyl Estradiol)
ifnbhmryyn(rjlskbccek) = kftjrmyxyi xvrctrjpwz (yzwxhnzxfm, 43.3)
-
05 Mar 2013
Placebo tablet
(Placebo Tablet)
ifnbhmryyn(rjlskbccek) = loljjamztj xvrctrjpwz (yzwxhnzxfm, 77.6)
Not Applicable
252
Self Management
(Self Management)
mmjhhooqeb(qzynzqjttt) = krakffqeyy ufgcyfawzk (wgerykzylp, 1.8)
-
11 Jul 2011
Targeted Self Management
(Targeted Self Management)
mmjhhooqeb(qzynzqjttt) = lltcngediu ufgcyfawzk (wgerykzylp, 2.0)
Phase 2
-
58
Levonorgestrel 90 mcg/Ethinyl Estradiol 20 mcg
hogxtihzfh(gcezwrofkh) = zkxwhamdfc xhciqrzzoo (vbcijrgsby )
-
01 Sep 2009
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