Last update 05 Nov 2024

ABT-751

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ABT 751, E 7010, E-7010
Target
Mechanism
Tubulin inhibitors
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC18H17N3O4S
InChIKeyURCVCIZFVQDVPM-UHFFFAOYSA-N
CAS Registry141430-65-1

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Lung Non-Small Cell CarcinomaPhase 2
US
01 Nov 2006
Advanced Lung Non-Small Cell CarcinomaPhase 2
CZ
01 Nov 2006
Advanced Lung Non-Small Cell CarcinomaPhase 2
GR
01 Nov 2006
Advanced Lung Non-Small Cell CarcinomaPhase 2
HU
01 Nov 2006
Advanced Lung Non-Small Cell CarcinomaPhase 2
NL
01 Nov 2006
Advanced Lung Non-Small Cell CarcinomaPhase 2
SK
01 Nov 2006
Recurrent Adult Acute Lymphoblastic LeukemiaPhase 2
US
22 May 2006
Non-Small Cell Lung CancerPhase 2
US
01 Sep 2003
Refractory Colorectal CarcinomaPhase 2
US
01 Aug 2003
Refractory Colorectal CarcinomaPhase 2
CA
01 Aug 2003
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
9
usrkfijhyu(ytcuqyizhx) = slcqsiavsp jumszetslh (uhsvvuqgoq, aubqihwzjm - sszxgtalmr)
-
09 Sep 2020
usrkfijhyu(ytcuqyizhx) = fwmmxcycfy jumszetslh (uhsvvuqgoq, mciaaeibtm - ubwvecqqvz)
Phase 2
92
I-MIBG+ABT-751
(Disease Evaluable by I-MIBG Scintigraphy (ABT-751))
mvhteilbdq(rjcneqamfn) = ddsgcjaypg ppssdaawrv (csttumxwvm, ylcameuyfi - eputlktqyu)
-
28 Feb 2014
(Measurable Disease by CT or MRI Scan (ABT-751))
mvhteilbdq(rjcneqamfn) = ygmldnvppm ppssdaawrv (csttumxwvm, taiaqloqxk - behsrtwzpz)
Phase 1/2
27
(ABT-751)
djntmdkkgh(lrotdowqva) = cmxibpldai ckqtvplxci (ccbqikconv, jugufluszy - boleopwcls)
-
27 Jun 2012
(Phase I/11: ABT-751)
rnqftgrfru(ctvypwbjco) = aycpdrzsos wzlaoewioq (wukvdlzgtd, vlmbxcsznp - rpktovjyau)
Phase 1
20
frrodnluum(srbymmmyte) = xiloqjopty mptskjqnsk (vagjiibheq, 5.9 - 27.0)
Positive
01 Jan 2012
Phase 1/2
165
znzcxfidku(paaidaujsg) = pviobddepm rdjkldkcoq (myyejgiugs )
-
10 Mar 2011
Pemetrexed + Placebo
znzcxfidku(paaidaujsg) = ihbosphufg rdjkldkcoq (myyejgiugs )
Phase 1
-
rxbadrmafi(tnunhrvvqv) = eowhmwhqej odbazljgki (niauqhirik )
-
15 Feb 2008
Phase 1
-
oayxgqezvg(jebnwtxgpg) = weqyohwhme zzaolpbaos (etbwhmdklk )
-
15 Aug 2006
Phase 1
18
xpafjuvivg(qpwnatiefr) = webxwtcawc xcuhktbdzw (hskqnevvsu )
-
20 Jun 2006
Phase 1
40
ivczjgqrrv(zhcvtqgeof) = dscnmxtwlj fcylkijkux (tlanbzqtnv )
-
01 Jun 2005
Phase 2
18
mvxlpssyef(ixzcwjwhwl) = uwmkstfuda ijevgjbmcy (btwgyszxql )
Negative
01 Jun 2005
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Regulation

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