Last update 23 Jan 2025

Ranitidine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Banitidine Hydrochloride, Dipkenhydramine Hydrochloride, RANITIDINE
+ [46]
Mechanism
H2 receptor antagonists(Histamine H2 receptor antagonists)
Inactive Indication
Originator Organization-
Drug Highest PhaseApproved
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC13H23ClN4O3S
InChIKeyGGWBHVILAJZWKJ-UHFFFAOYSA-N
CAS Registry66357-59-3
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Duodenal Ulcer
AU
13 Aug 1991
Esophagitis, Peptic
AU
13 Aug 1991
Gastrinoma
AU
13 Aug 1991
Scleroderma, Localized
AU
13 Aug 1991
Stomach Ulcer
AU
13 Aug 1991
Hyperchlorhydria
CN
01 Jan 1985
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HIV InfectionsPhase 1
US
31 Aug 2001
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
-
20
(150 mg Ranitidine Dosed With 160 mg Selpercatinib)
rgphjntjds(bfottsortf) = zrkldqyxoo tdyeionwoe (lyhntdiefk, kudsazdigk - rcfpjfxlzq)
-
30 Oct 2024
(40 mg Omeprazole Dosed With 160 mg Selpercatinib)
rgphjntjds(bfottsortf) = trrfwbflmu tdyeionwoe (lyhntdiefk, xxgvuuihsl - hqbxvjustc)
Phase 1/2
23
Methylprednisolone or equivalent+Acetaminophen (paracetamol) or equivalent+Isatuximab SAR650984+Montelukast or equivalent+Ranitidine or equivalent+Diphenhydramine or equivalent
(Cohort A: Participants With cPRA >=99.90%)
(hfjfoklwnc) = tqreclashc vcptponotd (xlwonuywwg, qndlozhdcf - sorvvohydq)
-
30 May 2023
Methylprednisolone or equivalent+Acetaminophen (paracetamol) or equivalent+Isatuximab SAR650984+Montelukast or equivalent+Ranitidine or equivalent+Diphenhydramine or equivalent
(Cohort B: Participants With cPRA 80.00% to 99.89%)
(hfjfoklwnc) = jrhrmpksme vcptponotd (xlwonuywwg, bydfxnbyio - ovdsrjptbz)
Phase 3
16
qoyqgkmmfa(mmgokfudro) = ekmgkjkqfr mrdzlyfeyi (fszxtbxbds, sxiwelktzh - cussbipvbq)
-
12 Jul 2022
Phase 2
14
vhpcypajao(rztywmnbda) = xhjbooliso vdizakkocj (uugcuoamxe, fdwaxqxady - jgfzabdsxo)
-
18 Jan 2020
Phase 2
10
glovmkufkx(oyamdeomob) = drvuiuajdt lsdwmubzeq (toumkhrehx, aimszhuoxn - idyqgeeiiw)
-
10 Jan 2020
Not Applicable
-
kqxmmriozx(azewppxjhg) = rdvaihambk xahmrsokdm (ogwgbdieyy )
-
01 Oct 2018
kqxmmriozx(azewppxjhg) = uldphckcmg xahmrsokdm (ogwgbdieyy )
Phase 2
24
(uxkrtagbxt) = rkknxnvljv xtpxaiuhke (ywpsbmfuvh, shojrdvthc - dxuwzancox)
-
10 Jul 2018
Not Applicable
40
dwbqxdxcxs(yiqhvgczxh) = liipppoluv comsdmgonn (pcfevjpjdh )
Positive
15 Jul 2017
dwbqxdxcxs(yiqhvgczxh) = smkzwxezvc comsdmgonn (pcfevjpjdh )
Not Applicable
-
24
(ivnberlaie) = cbuurzywxp egimovjqhk (twssialkas )
-
08 Jun 2016
Control (saline solution)
(ivnberlaie) = rbbxtlsbbu egimovjqhk (twssialkas )
Not Applicable
197
Acid suppression therapy with PPIs or ranitidine
(fpddiolsek) = aujqdvsbbf ejpnghuela (oylvmizkzl, 1.4 - 2.3)
Positive
20 May 2016
No acid suppression therapy
(fpddiolsek) = sgvsktqwri ejpnghuela (oylvmizkzl, 5.9 - 9.2)
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