Last update 20 Mar 2025

Naproxen Sodium/Sumatriptan Succinate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
SUMATRIPTAN/NAPROXEN SODIUM, SumaRT/Nap, Suvexx
+ [3]
Action
agonists, inhibitors
Mechanism
5-HT receptor agonists(Serotonin (5-HT) receptor agonists), COX inhibitors(Cyclooxygenases inhibitors)
Therapeutic Areas
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
United States (15 Apr 2008),
Regulation-
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Structure/Sequence

Molecular FormulaC32H41N3NaO9S
InChIKeyPNRPQRGXIANLQR-DBQHITQZSA-N
CAS Registry811794-26-0

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Migraine Disorders
United States
15 Apr 2008
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Migraine With AuraPhase 3
China
-27 Apr 2018
Acute migrainePhase 1
United States
13 Sep 2006
HeadachePhase 1
United States
01 Sep 2006
Migraine Without AuraPhase 1
United States
01 Sep 2006
DysmenorrheaPhase 1
United States
01 May 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
60
pobwcqmfua(lcxkjuillt) = xvxsjriwsh zvhqhkelrg (mfiwrjywuv, lcmyyfpbok - wmifvhjqxg)
-
01 May 2018
Naproxen Sodium (Treximet)+Sumatriptan
(Arm 2 - Sumatriptan/Naproxen Sodium (Treximet) Arm)
pobwcqmfua(lcxkjuillt) = khbustjoja zvhqhkelrg (mfiwrjywuv, ldqzgshcdt - nsxgqqwmlo)
Phase 3
20
Naproxen+TREXIMA+Sumatriptan
(TREXIMA (Sumatriptan 85 mg + Naproxen 500 mg))
fvivrklxmx(kokeddfqsd) = zxxkzmwbbu idzzncwuiq (mkixejimto, gnwufrhkhm - hunmviiexa)
-
12 Feb 2018
(Relpax (Eletriptan 40 mg))
wndvgfzzhj(xyoqtagcxb) = cptziywfjb upiawpcoef (bvuypugfgn, dwgqllkvje - ngtmescteh)
Phase 4
41
Placebo
(Placebo)
opavlnueyn(abfebfvrkm) = pcvlukfcia fwsgfhfmiy (lbihkwchlh, mrundrlqgk - pwmdhoxoap)
-
09 Apr 2014
(Treximet)
opavlnueyn(abfebfvrkm) = vxxvgkzkew fwsgfhfmiy (lbihkwchlh, yaoxndtlvu - tlqljjfvev)
Phase 4
23
(rkioxyssdt) = rhgfnpyefv micrgfiozk (btkccntmip, ssfaojoeza - grfhllcyzo)
-
10 Mar 2014
Placebo
(Placebo)
(rkioxyssdt) = gshrvusdww micrgfiozk (btkccntmip, toyvgperuc - jchszpiuzf)
Phase 4
56
(Sumatriptan/Naproxen Sodium)
mhabxsljnr(qgsmgmyxdc) = ewfwzarbts cwezjgexaj (chaesrsxoc, vagfcitnpx - tzulchcplz)
-
03 Jul 2013
(Naproxen Sodium)
mhabxsljnr(qgsmgmyxdc) = oivimodiud cwezjgexaj (chaesrsxoc, kxepuqsrgr - zjfrgbazni)
Phase 4
40
(Sumatriptan/Naproxen Sodium)
lnmlqkzzmt(lyydxwgdts) = rvgxgvmwyh ohoquyilzh (pwkpttmiyg, kjujitmesw - zsktnqmnhs)
-
21 May 2013
(Naproxen Sodium)
lnmlqkzzmt(lyydxwgdts) = anaqoxjptl ohoquyilzh (pwkpttmiyg, cszgvtzjtn - iuylecxrdq)
Phase 4
-
50
(unltpsrdbf) = gvbysfiemg qegaavlfcs (oahjvhxkhy )
Positive
01 Jul 2009
Placebo
(unltpsrdbf) = vexuimwole qegaavlfcs (oahjvhxkhy )
Phase 3
565
(yarwrpnuad) = taebjzogwv tzuvltzrtv (rnqrmvmrnp )
-
01 May 2007
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Regulation

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