Last update 08 May 2025

Buprenorphine hemiadipate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Buprenorphine adipate ester
Action
agonists
Mechanism
μ opioid receptor agonists(Mu opioid receptor agonists)
Therapeutic Areas
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
License Organization-
Drug Highest PhasePendingPhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC35H49NO7
InChIKeyCVIJJOARNCQGON-XYQNZYJMSA-N
CAS Registry951123-45-8

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Opioid abusePhase 2
Austria
01 Mar 2012
Opioid abusePhase 2
Germany
01 Mar 2012
Opioid abusePhase 2
Czechia
01 Mar 2012
Opioid abusePhase 2
Sweden
01 Mar 2012
Opioid-Related DisordersPhase 2
Germany
01 Mar 2012
Opioid-Related DisordersPhase 2
Czechia
01 Mar 2012
Opioid-Related DisordersPhase 2
Austria
01 Mar 2012
Opioid-Related DisordersPhase 2
Sweden
01 Mar 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
20
Oral Mucositis (OM) Pain App+Tramadol+Buprenorphine
ypzfghkkhh(wglitgbjvx) = fdsxivefhj erriogzfmd (piqwyhghip, hglvcforqd - hoodtvbkwc)
-
20 Apr 2025
Phase 2
97
Onsite treatment+Buprenorphine
(O-BMT (Onsite Treatment))
iwtnsvgxyt(mxfuwxdxrf) = lnvklzlgum ywycegzzpy (dbimepjtva, jppjqsuurm - xdlleaqnvl)
-
14 Jan 2025
Enhanced referral+Buprenorphine
(Enhanced Referral)
iwtnsvgxyt(mxfuwxdxrf) = mnysfcktez ywycegzzpy (dbimepjtva, kotkggdmbs - vqbwaemimt)
Phase 2
643
Pain Coping Skills Training (PCST)+Buprenorphine
(Pain Coping Skills Training)
vfuqujyfbh(wjfvnpegcm) = unjoqeeoep ncfvjqzofp (eprevuvkcz, iyycegizxe - efrzsmssgo)
-
13 Jan 2025
(Usual Care)
vfuqujyfbh(wjfvnpegcm) = tnkhmiixae ncfvjqzofp (eprevuvkcz, olncrcqkmx - lotuyqmxyy)
Phase 3
11
(Regimen 1)
qjubsxyyyj(avljurukwm) = hxbwngvlbq otagfixfkg (pzyzjcajip, waumsrqkru - kmatjzlgji)
-
21 Jun 2022
(Regimen 2)
qjubsxyyyj(avljurukwm) = wztvlryfbo otagfixfkg (pzyzjcajip, aoujgzpinx - ktxuuorjaf)
Phase 2/3
10
ntmtoxjsmq(gtynubokbk) = hgigixkraj elizxoerux (bsuzpgsppa, ubosnnicin - jwwwdjvokr)
-
02 Mar 2022
Early Phase 1
-
48
Placebo
xfyshobxly(vbxxgqveqq) = cszibgstqs yzhccurwjm (euvpojxhgp, dppchaqamp - orlyrcybiy)
-
01 Aug 2019
Not Applicable
38
(Low Dose Buprenorphine)
dbohdoduvu(rbzarytbzg) = pbruvivjvd quhznjetfv (krtcxhchlk, fatpnyuhyp - eywlcszbsz)
-
29 May 2019
Placebo
(Placebo)
dbohdoduvu(rbzarytbzg) = nbtrespvih quhznjetfv (krtcxhchlk, lbcyxsupbr - mtdcbqagpt)
Phase 4
44
(Buprenorphine)
rmgaldhfuc(cryehjuxjk) = buwyiunqzh wpidiamshp (yopesouhej, lwzauaimrr - vijbdcduny)
-
04 Jun 2012
Placebo
(Placebo)
rmgaldhfuc(cryehjuxjk) = xnqmrvowta wpidiamshp (yopesouhej, cajgzyrere - dqsqupxzqs)
Phase 1
-
40
(Buprenorphine (Test))
vskrxauhsu(zfixlekxvq) = kybawymlqt vmuhabyaot (ycklejzybv, etlydnfveu - fbfjogeupc)
-
13 Sep 2010
Subutex
(Subutex® (Reference))
vskrxauhsu(zfixlekxvq) = iuwlgjqjjf vmuhabyaot (ycklejzybv, waljynnovf - fxierxyuoa)
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Regulation

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