Drug Type Small molecule drug |
Synonyms (Z)-Capsaicin, cis-Capsaicin, Civamide + [6] |
Target |
Action agonists |
Mechanism TRPV1 agonists(Vanilloid receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date Canada (15 Jul 2010), |
RegulationOrphan Drug (United States) |
Molecular FormulaC18H27NO3 |
InChIKeyYKPUWZUDDOIDPM-VURMDHGXSA-N |
CAS Registry25775-90-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D06388 | Zucapsaicin |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Osteoarthritis | Canada | - | 15 Jul 2010 |
Pain | Canada | - | 15 Jul 2010 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Osteoarthritis, Knee | Phase 3 | - | 01 Jun 2003 | |
Cluster Headache | Phase 3 | United States | 01 Jan 2002 | |
Dry Eye Syndromes | Phase 2 | United States | 01 May 2014 | |
Trigeminal Neuralgia | Phase 2 | United States | 01 Mar 2014 | |
Neuralgia, Postherpetic | Phase 2 | United States | 01 Mar 2009 | |
Neuralgia, Postherpetic | Phase 2 | Canada | 01 Mar 2009 | |
Post-traumatic neuralgia | Phase 2 | United States | 01 Mar 2009 | |
Post-traumatic neuralgia | Phase 2 | Canada | 01 Mar 2009 |
Phase 2 | 232 | nuldabkmex(ozntyvqauy) = cctbmqlgyw dnfxptuhbj (daqwwrumqd, 1.13) View more | - | 01 Dec 2023 | |||
Phase 2 | 63 | Combination pharmacotherapy - transdermal nicotine patch + nicotine gum+Nicotine replacement therapy - nicotine gum+Varenicline+Bupropion Sustained Release+Nicotine replacement therapy - transdermal nicotine patch (Tailored Intervention Group) | rdxtzggkhh = jggtsjjyao rmhykjybhh (subbsssysr, piykrdymor - hdidbujcqy) View more | - | 19 Jul 2017 | ||
Combination pharmacotherapy - transdermal nicotine patch + nicotine gum+Nicotine replacement therapy - nicotine gum+Varenicline+Bupropion Sustained Release+Nicotine replacement therapy - transdermal nicotine patch (Enhanced Standard of Care Group) | rdxtzggkhh = prayubwokz rmhykjybhh (subbsssysr, okhaydnucb - swblcbfwps) View more | ||||||
Phase 2 | 11 | (Double Blind Treatment Period Civamide Nasal Spray) | wryhseytqk(esyscnftaq) = vhvxezogec sjpupluzlg (ztdbayehck, 0.84) View more | - | 01 Mar 2017 | ||
Placebo (Double Blind Treatment Period Placebo Nasal Spray) | wryhseytqk(esyscnftaq) = gykpgwmvlv sjpupluzlg (ztdbayehck, 1.02) View more |