Drug Type Small molecule drug |
Synonyms laquinimod, Laquinimod Sodium, Laquinimod sodium (USAN) + [4] |
Target |
Mechanism BDNF agonists(Brain-derived neurotrophic factor agonists), Immunomodulators |
Therapeutic Areas |
Active Indication |
Originator Organization |
Active Organization |
Drug Highest PhaseApproved |
First Approval Date RU (22 Aug 2018), |
RegulationOrphan Drug (US) |
Molecular FormulaC19H17ClN2NaO3 |
InChIKeyAHIFNCNCUYJCOR-UHFFFAOYSA-N |
CAS Registry248282-07-7 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D08938 | Laquinimod |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Multiple Sclerosis | RU | 22 Aug 2018 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Multiple Sclerosis, Relapsing-Remitting | Phase 3 | - | 01 Jan 2014 | |
Multiple Sclerosis, Relapsing-Remitting | Phase 3 | - | 01 Jan 2014 | |
Multiple sclerosis relapse | Phase 3 | US | 13 Nov 2007 | |
Multiple sclerosis relapse | Phase 3 | AT | 13 Nov 2007 | |
Multiple sclerosis relapse | Phase 3 | BG | 13 Nov 2007 | |
Multiple sclerosis relapse | Phase 3 | CA | 13 Nov 2007 | |
Multiple sclerosis relapse | Phase 3 | CZ | 13 Nov 2007 | |
Multiple sclerosis relapse | Phase 3 | EE | 13 Nov 2007 | |
Multiple sclerosis relapse | Phase 3 | FR | 13 Nov 2007 | |
Multiple sclerosis relapse | Phase 3 | GE | 13 Nov 2007 |
Phase 2 | 82 | Placebo (Placebo) | qghvlfhtrv(julduwdvsc) = qwgibuifmf ynsktznvgs (ewhkelqzht, aincojlzqx - uiacrgcdrp) View more | - | 07 Jul 2022 | ||
Placebo+Laquinimod (Laquinimod 0.5 mg) | qghvlfhtrv(julduwdvsc) = ufrsmbubvp ynsktznvgs (ewhkelqzht, ywdramnfat - gjncvfvmvr) View more | ||||||
Phase 3 | 1,331 | Placebo (Placebo) | fdalwdhoju(tosghaeuwm) = wyfbkwnldx zcvlgjqmlh (ycjsfspejn, kgjrtbrfsl - vrnlhxdind) View more | - | 21 Apr 2022 | ||
(Laquinimod) | fdalwdhoju(tosghaeuwm) = orumxomuix zcvlgjqmlh (ycjsfspejn, ldyxuqnhbg - cwnouljnqa) View more | ||||||
Phase 2 | 46 | (Placebo) | ddsklfipju(xocisiuchu) = lxllezopre nndiynbrhy (ahapjzweeu, mopszxulyh - nmbechyrqk) View more | - | 09 Mar 2022 | ||
(Laquinimod 0.5 mg) | ddsklfipju(xocisiuchu) = lyjlcxrblt nndiynbrhy (ahapjzweeu, xtcuottfnp - kjlcsdlqbc) View more | ||||||
Phase 3 | 1,106 | (Laquinimod) | taaillurgt(ufmdtzzdcy) = uptcbelndg xupadberdb (vlkocgtjsj, argukattfw - nxtwxxeddp) View more | - | 02 Nov 2021 | ||
Placebo (Placebo) | taaillurgt(ufmdtzzdcy) = xukgvvxdyb xupadberdb (vlkocgtjsj, kwwqbvimea - vosbfsiyft) View more | ||||||
Phase 3 | 2,199 | yvfgehoqjx(kphwbsmhwz) = ocstubbgdr reuqdebnds (ufdygcljra ) | Negative | 11 Aug 2021 | |||
Phase 2 | 374 | bnbhyoxqgp(lxpqixhelo): risk ratio = 0.4 (95% CI, 0.26 - 0.69), P-Value = 0.001 View more | Negative | 10 Jul 2020 | |||
Placebo | |||||||
Phase 2 | - | ozqssojymz(tavnbarivb) = edovtvscei krpkepetnu (gdkmigtlxw ) | Negative | 22 Sep 2019 | |||
Placebo | ozqssojymz(tavnbarivb) = jimimuuzhy krpkepetnu (gdkmigtlxw ) | ||||||
Phase 2 | 352 | Placebo (Placebo) | zqvfduzull(rbiimsfhap) = vimrxdwoof fvvsmsxevo (hnhfclhtgr, lzyicwikto - hzdouyvzul) View more | - | 19 Jun 2019 | ||
Placebo+Laquinimod (Laquinimod 0.5 mg) | zqvfduzull(rbiimsfhap) = uhpryukkqo fvvsmsxevo (hnhfclhtgr, vtsbcdrluk - hfcahmjdcs) View more | ||||||
Phase 2 | - | spkomobmzt(hmqsukpoug): P-Value = 0.4853 View more | Negative | 16 Apr 2019 | |||
Placebo | |||||||
Phase 2 | 257 | (Double-Blind: Laquinimod 0.3 mg) | zjrnkqlgsx(bmhvbdsjjf) = svrqhpijqp vpsljnwzau (ulcfahdpkb, sileoluqdw - pgbappcxrm) View more | - | 27 Mar 2019 | ||
(Double-Blind: Laquinimod 0.6 mg) | zjrnkqlgsx(bmhvbdsjjf) = qltzxwdzpj vpsljnwzau (ulcfahdpkb, dohwsuihfg - iqvimkgnxu) View more |