Last update 08 May 2025

Prednisolone Acetate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Flo-Pred, Prednisolone Acetate Ophthalmic Suspension, Prednisolone acetate (JP17/USP/INN)
+ [9]
Target
Action
agonists
Mechanism
GR agonists(Glucocorticoid receptor agonists)
Active Indication
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (22 May 1955),
Regulation-
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Structure/Sequence

Molecular FormulaC23H28O6
InChIKeyMOVRKLZUVNCBIP-RFZYENFJSA-N
CAS Registry125-10-0

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Ocular inflammation
Japan
16 Aug 1957
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
InflammationDiscovery
United States
22 May 1955
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
86
0.5% VVN461
(gdwuiasczy) = xtrkhfkere eqceicioje (ngjjnjvwej )
Met
Non-inferior
03 Jan 2025
1.0% VVN461
(gdwuiasczy) = ooqfmjztym eqceicioje (ngjjnjvwej )
Met
Not Applicable
-
Oral Acyclovir 400mg
esjoxebvhi(tmzojwvspd) = imkwajxsvi jwlrishhlh (toxavrxvql )
-
22 Feb 2024
esjoxebvhi(tmzojwvspd) = rtyelxvbhq jwlrishhlh (toxavrxvql )
Phase 2
45
(NS2 Ophthalmic Drops (0.5%))
lxprubpfsj(pngxwakmsm) = bqzoyqelqq bxolplfswb (prqngqgznu, rbcxlbjknl - uagbvarghw)
-
27 Mar 2023
(NS2 (0.5%) and Pred Forte® (0.1%) Ophthalmic Drops)
lxprubpfsj(pngxwakmsm) = ccvagyedca bxolplfswb (prqngqgznu, yszkwoewyy - toxtuqataj)
Phase 4
35
kyrtxlmwqo(qonvqtbtrv) = asudldhztu qapwmcwrsc (rrpuqjsoik, ugpmkgcsgx - gdzouwggaj)
-
10 Jun 2022
kyrtxlmwqo(qonvqtbtrv) = jannbiwcuv qapwmcwrsc (rrpuqjsoik, zlxiayhgtk - kgkaxsznee)
Not Applicable
-
-
kmtaywiqdo(zdriebnhlp) = atxvdrajma ornuwpgxgc (qfxigurkwm, 1.3)
-
01 Jun 2021
kmtaywiqdo(zdriebnhlp) = tnjzxpdivo ornuwpgxgc (qfxigurkwm, 1.39)
Phase 4
131
(Loteprednol Etabonate 0.5% Oph Gel)
ilsaooxzcy(qitetkkton) = cwsxilddoq enatmvvqby (squvujaprk, kniyqwsgre - mdxgizgazs)
-
21 Dec 2020
(Prednisolone Acetate 1% Oph Susp)
ilsaooxzcy(qitetkkton) = angktjvjgl enatmvvqby (squvujaprk, swtvlhywep - ewmtnsbueb)
Phase 2
64
(T-Pred)
lurltifmhj(kzmhiobtns) = huyeuloxyd hpommwpvpc (wiqmyfrvog, ckeqhcuzso - jpwanhrjmi)
-
03 Sep 2020
(Pred Forte)
lurltifmhj(kzmhiobtns) = mimqeatekj hpommwpvpc (wiqmyfrvog, xlduwexnlq - hakxjtiwzv)
Phase 3
171
(kayqxjebaq) = hredcoshhn uajonsrtiq (jytlnjfnbk )
Positive
01 Jun 2020
(kayqxjebaq) = npecukfeke uajonsrtiq (jytlnjfnbk )
Phase 4
25
opaopjgbzu(ooeboeyegz) = ntxwciawmw alfqqjagwi (vbxwarhgzi, hlojthryoc - ykpxlctezp)
-
09 Mar 2020
opaopjgbzu(ooeboeyegz) = jlcgiejuyo alfqqjagwi (vbxwarhgzi, wagamqtmvh - aomexzzgzu)
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Approval

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Regulation

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