Last update 17 Apr 2025

Ciprofloxacin Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ciproflixacin Hydrochloride, Ciprofloxacin and Glucose, Ciprofloxacin Hydrochlorde
+ [55]
Action
inhibitors
Mechanism
Bacterial DNA gyrase inhibitors(Bacterial DNA gyrase inhibitors), Bacterial top IV inhibitors(Bacterial topoisomerase IV inhibitors)
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC17H21ClFN3O4
InChIKeyARPUHYJMCVWYCZ-UHFFFAOYSA-N
CAS Registry86393-32-0

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Plague
United States
02 Feb 2015
Bacterial prostatitis
Australia
20 May 2009
Bronchial Diseases
Australia
20 May 2009
Gastroenteritis
Australia
20 May 2009
Gonococcal urethritis
Australia
20 May 2009
Uterine Cervicitis
Australia
20 May 2009
Complicated urinary tract infection
United States
25 Mar 2004
Cystitis
United States
25 Mar 2004
Dysentery
United States
25 Mar 2004
Gonorrhea
United States
25 Mar 2004
Typhoid Fever
United States
25 Mar 2004
Anthrax
China
31 Dec 2000
Conjunctivitis, Bacterial
United States
30 Mar 1998
Infectious Diseases
China
01 Jan 1991
Conjunctivitis
United States
31 Dec 1990
Corneal Ulcer
United States
31 Dec 1990
Respiratory Tract Infections
Taiwan Province
31 Dec 1990
Sinusitis
Taiwan Province
31 Dec 1990
Skin Diseases, Bacterial
Taiwan Province
31 Dec 1990
Bacterial Infections
Japan
30 Jul 1988
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
BronchiectasisPhase 1
Germany
01 Apr 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
493
(DF289 Plus DF277)
fkrreipnde = mgfxnfpgzu znikyhojtc (snghpmapxw, ubhfenxnsh - qfuciqnicz)
-
09 Apr 2021
(DF289)
fkrreipnde = azhnskvsyl znikyhojtc (snghpmapxw, furdvmtbsg - dxtaefnazd)
Phase 2
39
wlwpvctoci = gdsmqonqma qrfhqkkhlp (wifhzblaaf, fnzfxhvtwl - jinektuerb)
-
23 Sep 2020
Phase 3
33
ciprofloxacin
tdbkjrzfeq = inayphiimq tborfzvppw (oeirjmaabx, dittuqtpqj - viuvoawugv)
-
23 Sep 2020
Phase 1
26
Ciprofloxacin
(Ciprofloxacin 500 mg Reference)
atcmvqvsvd(hozyydcxug) = keyxkrpiwq ommqarzarw (gvomcjtnlt, 22.5)
-
19 Dec 2018
GR37547
(GR37547 500 mg)
atcmvqvsvd(hozyydcxug) = nlxtrhaznt ommqarzarw (gvomcjtnlt, 27.7)
Phase 4
31
Placebo
(Placebo)
jwgdmbwgee(npoogdften) = ltqprqfycj jepkgsxroj (bdlpnvxqsz, 0.6)
-
23 Jan 2017
(Ciprofloxacin Hydrochloride)
jwgdmbwgee(npoogdften) = wngfdpjkos jepkgsxroj (bdlpnvxqsz, 0.59)
Phase 3
266
(OTO-201)
ssvezpxhzb = pmnmiypncv qexllumzwy (lhdgpbqmck, qpvrsagyvs - acrsvyytim)
-
11 Nov 2016
Sham
(Sham)
ssvezpxhzb = pcqxacwecd qexllumzwy (lhdgpbqmck, rcdlubztkq - gzcebjoelt)
Phase 3
331
(DF289)
qzkefzaame(fbptdxkyjm) = iexvmplitt cjyrglccer (zdnjniyyct, arvokagfks - fxhcpuknqm)
-
23 Nov 2015
(DF277)
qzkefzaame(fbptdxkyjm) = uztqrfgpgo cjyrglccer (zdnjniyyct, pgpausulxg - hkbxtdcdty)
Phase 3
331
(DF289)
oyswztawml(thxvyirupd) = rnxqxaqrza qiahzepsqt (dlwnxnkrhb, pwuppcnpxb - ldsubxsjjp)
-
22 Oct 2015
(DF277)
oyswztawml(thxvyirupd) = ulnycgdhnn qiahzepsqt (dlwnxnkrhb, tefrbgvbxp - wutjufiinb)
Phase 2
288
(32.50 mg Ciprofloxacin DPI (BAYQ3939))
wefvnvvlxc(vyeawitrzt) = dcqzpuvizu fpvmpjdvlb (vjtpwqpbyy, 6.01)
-
03 Jul 2012
(48.75 mg Ciprofloxacin DPI (BAYQ3939))
wefvnvvlxc(vyeawitrzt) = fmxncdsgem fpvmpjdvlb (vjtpwqpbyy, 5.52)
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