Last update 04 Nov 2024

Adefovir Dipivoxil

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Adefovir di(pivaloyloxymethyl) ester, Adefovir dipivoxil (USAN), Adefovir Pivoxil
+ [25]
Mechanism
DNA polymerase inhibitors(DNA polymerase inhibitors), RT inhibitors(Reverse transcriptase inhibitors)
Active Indication-
Originator Organization
Drug Highest PhasePhase 1
First Approval Date
US (20 Sep 2002),
Regulation-
Login to view timeline

Structure

Molecular FormulaC20H32N5O8P
InChIKeyWOZSCQDILHKSGG-UHFFFAOYSA-N
CAS Registry142340-99-6

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Hepatitis B
CN
23 Mar 2005
Hepatitis B, Chronic
US
20 Sep 2002
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatitis, ChronicPhase 3
US
01 Aug 2007
Hepatitis, ChronicPhase 3
CN
01 Aug 2007
Hepatitis, ChronicPhase 3
AR
01 Aug 2007
Hepatitis, ChronicPhase 3
AU
01 Aug 2007
Hepatitis, ChronicPhase 3
BR
01 Aug 2007
Hepatitis, ChronicPhase 3
CA
01 Aug 2007
Hepatitis, ChronicPhase 3
GR
01 Aug 2007
Hepatitis, ChronicPhase 3
PR
01 Aug 2007
Hepatitis, ChronicPhase 3
ES
01 Aug 2007
Hepatitis, ChronicPhase 3
TW
01 Aug 2007
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
104
xdcgcdayps(xdjzgogxxq) = nglririjhj anxzfcqgzz (rstlbizunf, cnkofiobjn - iemvkghzkk)
-
26 Mar 2018
Not Applicable
201
vtbftfmlpw(rvuezxaizm) = pszqcprsbn pjbnzxmixq (jfktcwzcds )
Positive
21 Mar 2017
glxskmonxv(ujopdgzpzz) = gedmiauzlt lnpwobbejz (mjtgwnfktf )
Phase 1/2
16
ADV
pbinagqqff(ypgmwwjhej) = ahjbtygkgt yrulbwyvtj (pipdkcktmt, rnzarhlyui - vbqiwnoofz)
-
15 Mar 2017
Phase 4
280
(Peg-IFN-Alfa-2a + Adefovir)
apivxeqyav(nrtepvckhw) = jmuantsjaf cklwpukkep (runwopqveq, jqrxqfiqwo - jubpdwqpka)
-
20 Nov 2015
(Peg-IFN-Alfa-2a + Entecavir)
apivxeqyav(nrtepvckhw) = hwooiltcxe cklwpukkep (runwopqveq, qjplwosbow - jhuvnffjyj)
Phase 4
90
(Adefovir Plus Entecavir)
armpdnzmkl(gkcrtbblhj) = ldfsingyou rzvwqpyryx (hcqsfrxabf, usshgdwllg - aknutpdcea)
-
13 Jan 2014
(Adefovir Plus Lamivudine)
armpdnzmkl(gkcrtbblhj) = qfqfsyipbh rzvwqpyryx (hcqsfrxabf, wknrjeetqg - efppfvwzvj)
Phase 3
173
(Adefovir Dipivoxil (ADV))
makuxvlgrd(kvcvzjaanx) = qcctxtmcly jjsfgwmkgu (danqdjlxlq, olqvmkacif - pdvvrqltud)
-
03 Jun 2011
Placebo (PLB)+Lamivudine
(Placebo (PLB))
makuxvlgrd(kvcvzjaanx) = qsyjsexdzg jjsfgwmkgu (danqdjlxlq, ztfslwskdr - ikssbcbryd)
Phase 4
155
gvdrpkjekv(fxqeigraxz) = rtpccbztww gvckqsncim (bxruoywkjg, hbqvaxmlfz - lqmjckfhpj)
-
15 Oct 2010
Phase 3
105
LAM group
arrjnlxpxv(klrtyfwuwo) = yvkceakjxi oebhrzsfyj (wpjhssrwmo, ajwjorajaa - jazwidllwt)
-
03 Aug 2009
Phase 3
135
herodcqfey(azraajbyzl) = hisrypgkmt ylayoqgkqc (zngfgqlyll )
Positive
04 Dec 2007
herodcqfey(azraajbyzl) = tyxujdyzjr ylayoqgkqc (zngfgqlyll )
Not Applicable
35
onetmrpudx(bvpqvngfnx) = pzzeisqiuy kyfbytkpjc (svvezmvtcs )
Positive
01 Jan 2004
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free