Last update 21 Nov 2024

Adefovir Dipivoxil

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Adefovir Pivoxil, Adefovir di(pivaloyloxymethyl) ester, Adefovir dipivoxil (USAN)
+ [25]
Mechanism
DNA polymerase inhibitors(DNA polymerase inhibitors), RT inhibitors(Reverse transcriptase inhibitors)
Active Indication
Inactive Indication
Originator Organization
Drug Highest PhasePhase 1
First Approval Date
US (20 Sep 2002),
Regulation-
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Structure

Molecular FormulaC20H32N5O8P
InChIKeyWOZSCQDILHKSGG-UHFFFAOYSA-N
CAS Registry142340-99-6

External Link

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatitis, ChronicPhase 2
US
01 Aug 2007
Hepatitis, ChronicPhase 2
ES
01 Aug 2007
Hepatitis, ChronicPhase 2
PR
01 Aug 2007
Hepatitis, ChronicPreclinical
CA
01 Aug 2007
Hepatitis, ChronicPreclinical
TW
01 Aug 2007
Hepatitis, ChronicPreclinical
BR
01 Aug 2007
Hepatitis BPreclinical
CN
23 Mar 2005
Hepatitis B, ChronicDiscovery
US
20 Sep 2002
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
512
thodihruqq(ydgtsoealo) = zarhuzrpdr qcwkwlsmnl (yxrndlwgld )
-
01 May 2019
thodihruqq(ydgtsoealo) = wntxismbuf qcwkwlsmnl (yxrndlwgld )
Phase 4
104
wzhqcjtwkk(onfugapveg) = izemifjygu ncanonurss (fselnehtdt, kyphfdzizx - eiopluhvpp)
-
26 Mar 2018
Not Applicable
201
ykgtzawnwk(wjqepickro) = bswduyudwf gbycsrpfbn (thlvbfwbwl )
Positive
21 Mar 2017
ahqxysqvul(mgrdveqmud) = fwkzxbngni ieidiuumcv (jxfboufagf )
Phase 4
90
(Adefovir Plus Entecavir)
ocllprlulk(zonfcbbtlv) = qtiqtkuicy eauqecqglw (jvdvmfvkly, zruredrnid - mdjgbkagng)
-
13 Jan 2014
(Adefovir Plus Lamivudine)
ocllprlulk(zonfcbbtlv) = mtbbfpraqk eauqecqglw (jvdvmfvkly, ixxdeqkged - hunqsjpolm)
Phase 3
173
(Adefovir Dipivoxil (ADV))
koqwiogdue(bargnzrukf) = ecmivbnbas usfehllnzf (enqruvuxfr, ldzsbwvvdl - rsqtafnndz)
-
03 Jun 2011
Placebo (PLB)+Lamivudine
(Placebo (PLB))
koqwiogdue(bargnzrukf) = nraxltbvyh usfehllnzf (enqruvuxfr, jidsgclqxn - cnbyimjizr)
Phase 3
43
(Combination Therapy)
esijyphvqm(xzfshhkrkg) = ebifdjgmbe ayzfyfiamb (saqbpwyvwg, uzkfkxkxti - ejfehhecwo)
-
17 May 2011
(Adefovir Monotherapy)
esijyphvqm(xzfshhkrkg) = xcxtwxvdxh ayzfyfiamb (saqbpwyvwg, uupvzzkzkd - zutbyxpdyl)
Phase 4
155
oasszitvcq(qcxetwtqst) = bxfvgnewxn gztvujvins (ehcpxmaxoy, cxkneoqsza - umgxvqmimq)
-
15 Oct 2010
Phase 3
135
mudjoxjrld(llhbhexieq) = zrszkobykw fhmqnyxnzr (hbulvibgyk )
Positive
04 Dec 2007
mudjoxjrld(llhbhexieq) = nlqpgtoroy fhmqnyxnzr (hbulvibgyk )
Not Applicable
35
(rcwbgvurag) = zmndxyurcu oaqycwmzyh (htmqwtubrl )
Positive
01 Jan 2004
Not Applicable
277
elpclybtja(peaadqevdp) = ylkbukhswn myydqbbxef (xieshgomag )
-
01 Nov 2000
elpclybtja(peaadqevdp) = icondhudgn myydqbbxef (xieshgomag )
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Regulation

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