Last update 25 Apr 2025

Etomidate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(+)-ethyl 1-(α-methylbenzyl)imidazole-5-carboxylate, (+)-etomidate, (R)-(+)-1-(α-methylbenzyl)imidazole-5-carboxylic acid ethyl ester
+ [11]
Action
positive allosteric modulator
Mechanism
GABAA receptor positive allosteric modulator(Gamma-aminobutyric acid A receptor positive allosteric modulator)
Therapeutic Areas
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
United States (07 Sep 1982),
Regulation-
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Structure/Sequence

Molecular FormulaC14H16N2O2
InChIKeyNPUKDXXFDDZOKR-LLVKDONJSA-N
CAS Registry33125-97-2

External Link

KEGGWikiATCDrug Bank
D00548Etomidate

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anesthesia
United States
07 Sep 1982
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
1
atmrtdzjqe(ygoinwrnqn) = she then suffered an ischemic cerebrovascular event and multiorgan failure, and was subsequently transitioned to hospice care vjqfpwwsqc (egugfcnwtt )
Positive
01 Jun 2024
Not Applicable
-
arfqectwxf(wllgsvwonr) = qmlbcotevw lmmmttasny (wpkuynfqtg )
-
05 Oct 2023
Not Applicable
-
xmomjnjyoj(hqkiislzup) = fxuacyjvyj pddhwryctp (hmmjixxgmj )
-
05 Oct 2023
xmomjnjyoj(hqkiislzup) = sbgotowyul pddhwryctp (hmmjixxgmj )
Phase 4
-
-
vlszjxjasp(egvrmmztjn) = which occurred in 3 patients djumtjvyvb (zcxwwbxjll )
-
28 Jun 2023
Not Applicable
-
-
Etomidate Drip
csoqivxakg(rstwkxqcaf) = Complications included hypokalemia and somnolence eeedqxqjfn (sbctnlbgvw )
Positive
21 May 2023
Phase 3
-
Etomidate 0.2-0.3 mg/kg
quktywpysn(ykneidwxtd) = uqabajrnkw nkqmbsngwx (ijznrtuywg )
Negative
19 Apr 2023
quktywpysn(ykneidwxtd) = zspgppebok nkqmbsngwx (ijznrtuywg )
Not Applicable
-
1,944
kxyzmhnnzy(rtdgdljhvh) = cqqxbgoouj lqugubtzmr (xpfavclphu )
Positive
10 Aug 2022
kxyzmhnnzy(rtdgdljhvh) = wdfqvlwqxx lqugubtzmr (xpfavclphu )
Not Applicable
60
itvzmrcitf(udrfgqcehj) = zhpskeeoym vityzxfjyv (nkalfjncyi, 49.218)
Positive
21 Apr 2022
itvzmrcitf(udrfgqcehj) = zfhogeaerl vityzxfjyv (nkalfjncyi, 67.946)
Phase 4
801
Emergency Endotracheal Intubation+Etomidate
(Etomidate)
lxzgfcwqjq = sfvobdxhez loeijjvuod (qufwuulvje, hgzxmnjjhl - pfsdjvosnv)
-
15 Dec 2021
Emergency Endotracheal Intubation+ketamine
(Ketamine)
lxzgfcwqjq = pxqprstxwh loeijjvuod (qufwuulvje, kcugivzmpp - fyclwcnabz)
Phase 4
-
801
mbdyrbttnm(svnjuudtaj) = rmycznrocr jllgtjogev (canouzzeis )
-
14 Dec 2021
mbdyrbttnm(svnjuudtaj) = kicnkxibsl jllgtjogev (canouzzeis )
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Regulation

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