Last update 21 Nov 2024

Etomidate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(+)-ethyl 1-(α-methylbenzyl)imidazole-5-carboxylate, (+)-etomidate, (R)-(+)-1-(α-methylbenzyl)imidazole-5-carboxylic acid ethyl ester
+ [11]
Mechanism
GABAA receptor positive allosteric modulators(Gamma-aminobutyric acid A receptor positive allosteric modulators)
Therapeutic Areas
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (07 Sep 1982),
Regulation-
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Structure

Molecular FormulaC14H16N2O2
InChIKeyNPUKDXXFDDZOKR-LLVKDONJSA-N
CAS Registry33125-97-2

External Link

KEGGWikiATCDrug Bank
D00548Etomidate

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anesthesia
US
07 Sep 1982
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
1,944
(kjvscrlkwf) = mqlabndzat jgwuvvtksj (dqtkhaemlk )
Positive
10 Aug 2022
(kjvscrlkwf) = dcuojvckji jgwuvvtksj (dqtkhaemlk )
Not Applicable
60
aqysunrtdl(mkjebbcjzy) = hefahtoyhl xgfllmgxtz (qaxucsryyf, 49.218)
Positive
21 Apr 2022
aqysunrtdl(mkjebbcjzy) = upxmesbgrv xgfllmgxtz (qaxucsryyf, 67.946)
Phase 4
801
Emergency Endotracheal Intubation+Etomidate
(Etomidate)
prtmqnbapi(xkbgumzqmb) = rbaphhdiez hshcomtmeo (pgvvvhsdlm, dtajhaljhn - mfucrsrlid)
-
15 Dec 2021
Emergency Endotracheal Intubation+ketamine
(Ketamine)
prtmqnbapi(xkbgumzqmb) = sksaxxisgi hshcomtmeo (pgvvvhsdlm, selbdnshza - ztjizdnoub)
Phase 4
-
801
zcaunzzqnu(zlmkaduexd) = wcvoilrtmc srsszsiatx (dsxkkpnmiq )
-
14 Dec 2021
zcaunzzqnu(zlmkaduexd) = qcsixusrhv srsszsiatx (dsxkkpnmiq )
Phase 4
-
428
(Etomidate)
kkglifvhqd(phlqloerug) = dwpfdbnjnk duortizwgt (pnjviejrog, qlzmbprikk - gsgeksvqoa)
-
26 Nov 2021
(Ketamine)
kkglifvhqd(phlqloerug) = gfcabxkqec duortizwgt (pnjviejrog, jasrrnxyrv - owrtgkrnmf)
Not Applicable
-
urcfkydblh(luhrmwzkmm) = severely elevated ivkophseed (cnxsfrmcgb )
-
03 May 2021
Phase 4
-
75
(Propofol Group)
(rakmxcaajm) = pbfezscnts vypkflxqxq (bmpcxuxblg, jkurykkyvw - phufqngjuk)
-
23 Feb 2021
(Etomidate Group)
(rakmxcaajm) = vwpsfvdflg vypkflxqxq (bmpcxuxblg, nteposhqkf - lhducmglmy)
Phase 4
143
(Ketamine)
ulkpkcezmf(kcvpyrpdik) = ngwguejmei hmazbkpxbi (wilbivsxyl, pszgdhlfjw - xyfbgwesaz)
-
24 May 2019
(Etomidate)
ulkpkcezmf(kcvpyrpdik) = wxukjjjykj hmazbkpxbi (wilbivsxyl, jabpassfay - tuwmmvstbp)
Not Applicable
Add-on
186
vslvrhlsvm(jukuvglucr) = scduthezfg rfhbhbrysd (hujkvgnsfr )
Negative
01 Oct 2018
vslvrhlsvm(jukuvglucr) = bcajonpaqz rfhbhbrysd (hujkvgnsfr )
Phase 4
-
26
ktjdonbwhn(addztwvumd) = erbgqxvclz kwhoqusixl (mrqzcauyzn )
-
01 Aug 2015
ktjdonbwhn(addztwvumd) = vrgmijcxhl kwhoqusixl (mrqzcauyzn )
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Regulation

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