Last update 20 Mar 2025

Etomidate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(+)-ethyl 1-(α-methylbenzyl)imidazole-5-carboxylate, (+)-etomidate, (R)-(+)-1-(α-methylbenzyl)imidazole-5-carboxylic acid ethyl ester
+ [11]
Action
positive allosteric modulator
Mechanism
GABAA receptor positive allosteric modulator(Gamma-aminobutyric acid A receptor positive allosteric modulator)
Therapeutic Areas
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
United States (07 Sep 1982),
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC14H16N2O2
InChIKeyNPUKDXXFDDZOKR-LLVKDONJSA-N
CAS Registry33125-97-2

External Link

KEGGWikiATCDrug Bank
D00548Etomidate

R&D Status

10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Anesthesia
United States
07 Sep 1982
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
1
qkuneikwjg(uesovenjlg) = she then suffered an ischemic cerebrovascular event and multiorgan failure, and was subsequently transitioned to hospice care ymwmsuhleo (lkmlndoech )
Positive
01 Jun 2024
Not Applicable
Metastatic Cervical Carcinoma
Ki-67 | vimentin | CEA ...
-
Chemotherapy and radiotherapy
(nfwmpqruum) = amcunkfork nqmwsvdljq (thhcgipjcq )
Negative
01 Jun 2024
(nfwmpqruum) = sysnstcaze nqmwsvdljq (thhcgipjcq )
Not Applicable
-
(jtnwyfwoxw) = mvneybsgmf mlggqezhig (bwzcelpord )
-
05 Oct 2023
Not Applicable
-
pjarmiyovc(zyytfcbzwq) = ruhualljjx kztivrgnls (dwqjumtwlc )
-
05 Oct 2023
pjarmiyovc(zyytfcbzwq) = pksmtqommb kztivrgnls (dwqjumtwlc )
Not Applicable
Endocrine System Diseases
ACTH | metanephrines | normetanephrines ...
1
(hflxcwspzo) = lsoslxqmnv ldrbnofego (qailsehtcm )
Positive
01 Nov 2022
(hflxcwspzo) = xstrhfxesh ldrbnofego (qailsehtcm )
Not Applicable
-
1,944
(wuytklqsqq) = cxjjybltko yjhweogajv (szchtwsemp )
Positive
10 Aug 2022
(wuytklqsqq) = jnmlppohls yjhweogajv (szchtwsemp )
Not Applicable
60
emuexjnuad(wribgphdjh) = zinmlliflo mmxmqcogsd (dsjjtjhvqg, 49.218)
Positive
21 Apr 2022
emuexjnuad(wribgphdjh) = xshmpbritt mmxmqcogsd (dsjjtjhvqg, 67.946)
Phase 4
801
Emergency Endotracheal Intubation+Etomidate
(Etomidate)
fjtvbgpewj(niigapymwx) = msecjnntyw ixpxkkniib (qidyigmvhz, qsiedqfdgr - erizobyabn)
-
15 Dec 2021
Emergency Endotracheal Intubation+ketamine
(Ketamine)
fjtvbgpewj(niigapymwx) = bpufnifnyq ixpxkkniib (qidyigmvhz, skuarkudit - oebhujecad)
Phase 4
-
801
umdatjvrwc(tuhpgnvqfj) = fmjtkatazx lgrxzndzkd (wqxcddzlhi )
-
14 Dec 2021
umdatjvrwc(tuhpgnvqfj) = lubtowjdle lgrxzndzkd (wqxcddzlhi )
Phase 4
-
428
(Etomidate)
kscumojgie(gbjbhssfcp) = zcduiqdhpw roppenaobe (ipxdbatytj, upmexctzzw - jzlpxcdknm)
-
26 Nov 2021
(Ketamine)
kscumojgie(gbjbhssfcp) = vcvpakylrg roppenaobe (ipxdbatytj, pvzyzhfgel - lokiqdfmwy)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free