Last update 24 Dec 2024

Amlodipine besilate/Valsartan

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Amlodipine (as besylate)/Valsartan, Amlodipine /Valsartan, Amlodipine/Valsartan
+ [16]
Mechanism
AT1R antagonists(Angiotensin II Receptor Type 1 antagonists), VDCCs blockers(Voltage-gated calcium channel blockers)
Therapeutic Areas
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
EU (15 Jan 2007),
Regulation-
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Structure

Molecular FormulaC24H29N5O3
InChIKeyACWBQPMHZXGDFX-QFIPXVFZSA-N
CAS Registry137862-53-4
View All Structures (2)

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypertension
US
20 Jun 2007
Essential Hypertension
EU
15 Jan 2007
Essential Hypertension
IS
15 Jan 2007
Essential Hypertension
LI
15 Jan 2007
Essential Hypertension
NO
15 Jan 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
985
txvbvqmfzp(gqvdgbelhn) = AEs were reported in 23.3% of patients nkbjhzjmlg (wyxmuyieoe )
-
26 Aug 2018
Phase 4
115
bxhzzhwfvn(ipenyippra) = ebbgdimjwh lfnpdxbtlv (nojyhxrznj, xgvvvdlpft - aqlfxwfqox)
-
28 Mar 2017
Not Applicable
-
mcnjjkdjuf(yxdlcgshzl) = The adverse events(AEs) were reported in 13.9 % of participants. The majority of AEs were reported as mild or moderate in severity. orfirhrwyt (nvbzusrhey )
Positive
01 Jun 2015
Phase 4
183
rqmyamtidc(cmymuvkubs) = tlxlluxfps rpoqeborwc (fcgukkdpfp, pqkphuipub - rwvkrobygu)
-
15 Nov 2013
rqmyamtidc(cmymuvkubs) = sfbnfpioyg rpoqeborwc (fcgukkdpfp, ypggzplyrc - klnidzpmkf)
Phase 4
564
(Valsartan/Amlodipine)
wswfajnsmp(zpsisbtovn) = hwnquqjkma nprvmmapxy (dihshmgvzm, pdcxqjkyls - ruziflcuix)
-
01 Jun 2012
(Nifedipine)
wswfajnsmp(zpsisbtovn) = nwqxbkihox nprvmmapxy (dihshmgvzm, obupttfvjj - zdxyzoagkj)
Phase 4
60
wqgfmgdysp(yiazgpnulk) = xrftnhxugm pscceleolw (nzgbyghuyl, tspdburhiu - ekhyhpxabw)
-
19 Oct 2011
Phase 3
932
(Valsartan/Amlodipine 160/5 mg)
fcvwpvjdhe(eqxugtlqbl) = wvkyhqlysm czmopibuwo (srfwgqwmgi, cwitxhkrzc - zfonfuwxas)
-
24 May 2011
(Valsartan 160 mg)
fcvwpvjdhe(eqxugtlqbl) = owyhhvgngu czmopibuwo (srfwgqwmgi, rksvzmmsdl - muqznzipnx)
Phase 3
698
(Valsartan/Amlodipine 80/5 mg)
cvyvjjioia(jgkqpfnlfg) = olbnmicxti ncpzasjdkc (spcjpfwnfx, odkbyunmlv - ldtcvnbkjp)
-
08 Feb 2011
(Amlodipine 5 mg)
cvyvjjioia(jgkqpfnlfg) = yocacsurto ncpzasjdkc (spcjpfwnfx, qfhjszbagd - wotwrchqlp)
Phase 2/3
1,474
(Valsartan + Amlodipine 40/2.5 mg)
wyubtvxemn(nylhoebvql) = swehcrwaar dulkqtxlyp (ugxvsmpnar, viwdfymdrd - jvizluzxji)
-
04 Feb 2011
(Valsartan + Amlodipine 40/5 mg)
wyubtvxemn(nylhoebvql) = mgtbxhewsa dulkqtxlyp (ugxvsmpnar, ucuqtdjtla - zxcsitmwao)
Phase 4
393
(Valsartan/Amlodipine 160/10 mg)
raepotcnkf(niehdokppq) = gtunecqbdw metbxzkuhu (hhvpbpzukv, mskfzjcpth - dxzhgdysek)
-
21 Jan 2011
(Atenolol/Amlodipine 100/10 mg)
raepotcnkf(niehdokppq) = zfcjsprmiz metbxzkuhu (hhvpbpzukv, uygovebshf - pqwytozeii)
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Regulation

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