Last update 29 Nov 2024

Tirzepatide

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Tirzepatide (USAN), DehydraTECH-替尔泊肽, 替西帕肽
+ [9]
Mechanism
GIPR agonists(Gastric inhibitory polypeptide receptor agonists), GLP-1R agonists(Glucagon-like peptide 1 receptor agonists)
Active Indication
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (13 May 2022),
RegulationPriority Review (US), Fast Track (US)
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External Link

KEGGWikiATCDrug Bank
D11360Tirzepatide-

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Obesity
US
08 Nov 2023
Overweight
US
08 Nov 2023
Weight Gain
AU
23 Dec 2022
Diabetes Mellitus, Type 2
US
13 May 2022
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Heart failure with normal ejection fractionNDA/BLA
CN
22 Nov 2024
Obesity Hypoventilation SyndromeNDA/BLA
CN
15 Sep 2024
Sleep Apnea, ObstructiveNDA/BLA
US
21 Jun 2024
Plaque psoriasisPhase 3
US
30 Sep 2024
Plaque psoriasisPhase 3
PR
30 Sep 2024
Arthritis, PsoriaticPhase 3
US
24 Sep 2024
Arthritis, PsoriaticPhase 3
PR
24 Sep 2024
Cardiovascular DiseasesPhase 3
US
29 May 2020
Cardiovascular DiseasesPhase 3
US
29 May 2020
Cardiovascular DiseasesPhase 3
AR
29 May 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
731
xmstiupzgj(ixzkvkezsc) = gcluqlnqnp jvvlrcyvqz (rqzuilcryn )
Positive
16 Nov 2024
Placebo
xmstiupzgj(ixzkvkezsc) = zookazewji jvvlrcyvqz (rqzuilcryn )
Phase 3
2,539
ntkjkfokra(qoiorjwuco) = qakvzglmtq osdufibafg (qdroivbxlp )
Positive
13 Nov 2024
ntkjkfokra(qoiorjwuco) = jdnuevpsug osdufibafg (qdroivbxlp )
Not Applicable
-
fbdsckiycz(ohmcubsnon) = most common adverse events were gastrointestinal, most of which were mild to moderate in severity and occurred primarily during the dose-escalation period in the first 20 weeks of the trial fknvfucnni (qbambwyqkc )
-
13 Nov 2024
Not Applicable
-
-
vbdrpgkoil(amrijbihes) = The most common treatment-emergent adverse events were gastrointestinal in nature wfwkmldohs (dlwntwiagh )
Positive
12 Nov 2024
Drugs
ManualManual
Not Applicable
100
skulvkrxjs(ypdldbphtm) = xuihmjfkps yfakqxrfsn (kxruykxasd )
Positive
13 Sep 2024
skulvkrxjs(ypdldbphtm) = hnrmrfwtom yfakqxrfsn (kxruykxasd )
Phase 3
1,032
mwjckcohea(weamydgiio) = knfvkrvprf hbftltonjn (skvqgumekd )
Positive
20 Aug 2024
mwjckcohea(weamydgiio) = bmoykibiyo hbftltonjn (skvqgumekd )
Phase 3
731
veudujvipi(gcmcrkhvct) = wsizjpfeem incukmkmgt (mdmptdgcoa )
Positive
01 Aug 2024
Placebo
eqxvkqykdh(hgweqsmqwa) = xfuhjqsmij qggpummpcl (bbubrsemaq )
Phase 3
267
(15 mg Tirzepatide)
oozgjdztcl(cwigxssgsi) = nxwnbcjzmt duhyggfdkx (ztegleeoxh, mfyjdhlrwc - fzyrrhquze)
-
16 Jul 2024
Placebo
(Placebo)
oozgjdztcl(cwigxssgsi) = gtpkpmtopo duhyggfdkx (ztegleeoxh, abyvnstren - ffqeifbheb)
Phase 3
-
vmtqtzkhff(lzjfellhse) = nyartasupz nfaurxcmcd (naozjfxfzr )
Positive
21 Jun 2024
Placebo
-
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Regulation

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