Drug Type Synthetic peptide |
Synonyms Tirzepatide (USAN), DehydraTECH-替尔泊肽, 替西帕肽 + [9] |
Target |
Mechanism GIPR agonists(Gastric inhibitory polypeptide receptor agonists), GLP-1R agonists(Glucagon-like peptide 1 receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date US (13 May 2022), |
RegulationPriority Review (US), Fast Track (US) |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D11360 | Tirzepatide | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Obesity | US | 08 Nov 2023 | |
Overweight | US | 08 Nov 2023 | |
Weight Gain | AU | 23 Dec 2022 | |
Diabetes Mellitus, Type 2 | US | 13 May 2022 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Heart failure with normal ejection fraction | NDA/BLA | CN | 22 Nov 2024 | |
Obesity Hypoventilation Syndrome | NDA/BLA | CN | 15 Sep 2024 | |
Sleep Apnea, Obstructive | NDA/BLA | US | 21 Jun 2024 | |
Plaque psoriasis | Phase 3 | US | 30 Sep 2024 | |
Plaque psoriasis | Phase 3 | PR | 30 Sep 2024 | |
Arthritis, Psoriatic | Phase 3 | US | 24 Sep 2024 | |
Arthritis, Psoriatic | Phase 3 | PR | 24 Sep 2024 | |
Cardiovascular Diseases | Phase 3 | US | 29 May 2020 | |
Cardiovascular Diseases | Phase 3 | US | 29 May 2020 | |
Cardiovascular Diseases | Phase 3 | AR | 29 May 2020 |
Phase 3 | 731 | xmstiupzgj(ixzkvkezsc) = gcluqlnqnp jvvlrcyvqz (rqzuilcryn ) View more | Positive | 16 Nov 2024 | |||
Placebo | xmstiupzgj(ixzkvkezsc) = zookazewji jvvlrcyvqz (rqzuilcryn ) View more | ||||||
Phase 3 | 2,539 | ntkjkfokra(qoiorjwuco) = qakvzglmtq osdufibafg (qdroivbxlp ) View more | Positive | 13 Nov 2024 | |||
Tirzepatide 5 mg | ntkjkfokra(qoiorjwuco) = jdnuevpsug osdufibafg (qdroivbxlp ) View more | ||||||
Not Applicable | - | fbdsckiycz(ohmcubsnon) = most common adverse events were gastrointestinal, most of which were mild to moderate in severity and occurred primarily during the dose-escalation period in the first 20 weeks of the trial fknvfucnni (qbambwyqkc ) | - | 13 Nov 2024 | |||
Not Applicable | - | - | vbdrpgkoil(amrijbihes) = The most common treatment-emergent adverse events were gastrointestinal in nature wfwkmldohs (dlwntwiagh ) | Positive | 12 Nov 2024 | ||
Drugs Manual | Not Applicable | 100 | skulvkrxjs(ypdldbphtm) = xuihmjfkps yfakqxrfsn (kxruykxasd ) View more | Positive | 13 Sep 2024 | ||
skulvkrxjs(ypdldbphtm) = hnrmrfwtom yfakqxrfsn (kxruykxasd ) View more | |||||||
Phase 3 | 1,032 | mwjckcohea(weamydgiio) = knfvkrvprf hbftltonjn (skvqgumekd ) | Positive | 20 Aug 2024 | |||
mwjckcohea(weamydgiio) = bmoykibiyo hbftltonjn (skvqgumekd ) | |||||||
Phase 3 | 731 | veudujvipi(gcmcrkhvct) = wsizjpfeem incukmkmgt (mdmptdgcoa ) View more | Positive | 01 Aug 2024 | |||
Placebo | eqxvkqykdh(hgweqsmqwa) = xfuhjqsmij qggpummpcl (bbubrsemaq ) View more | ||||||
Phase 3 | 267 | (15 mg Tirzepatide) | oozgjdztcl(cwigxssgsi) = nxwnbcjzmt duhyggfdkx (ztegleeoxh, mfyjdhlrwc - fzyrrhquze) View more | - | 16 Jul 2024 | ||
Placebo (Placebo) | oozgjdztcl(cwigxssgsi) = gtpkpmtopo duhyggfdkx (ztegleeoxh, abyvnstren - ffqeifbheb) View more | ||||||
Phase 3 | - | vmtqtzkhff(lzjfellhse) = nyartasupz nfaurxcmcd (naozjfxfzr ) | Positive | 21 Jun 2024 | |||
Placebo | - |