Last update 25 Mar 2025

Saruparib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
AZD-5305, AZD5305
Target
Action
inhibitors
Mechanism
PARP1 inhibitors(Poly (ADP-Ribose) polymerase 1 inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC22H26N6O2
InChIKeyWQAVGRAETZEADU-UHFFFAOYSA-N
CAS Registry2589531-76-8

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced breast cancerPhase 3
United States
01 Aug 2024
Advanced breast cancerPhase 3
China
01 Aug 2024
Advanced breast cancerPhase 3
Japan
01 Aug 2024
Advanced breast cancerPhase 3
Argentina
01 Aug 2024
Advanced breast cancerPhase 3
Australia
01 Aug 2024
Advanced breast cancerPhase 3
Austria
01 Aug 2024
Advanced breast cancerPhase 3
Brazil
01 Aug 2024
Advanced breast cancerPhase 3
Bulgaria
01 Aug 2024
Advanced breast cancerPhase 3
Canada
01 Aug 2024
Advanced breast cancerPhase 3
Chile
01 Aug 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
Advanced Malignant Solid Neoplasm
PALB2 Mutation | RAD51C Mutation | BRCA2 Mutation | ...
141
uhgzjlofhh(ievfhzkfgq) = jyrqyjbblg kjrextwekd (wqrcvvsuwc, 35.7 - 61.3)
Positive
08 Apr 2024
Phase 1/2
48
xxglegmqux(xabtxkurpi) = dljtruxars gvvposexem (vfpsumoxbo )
Positive
25 Jan 2024
Phase 1
Ovarian Cancer | Endometrial Carcinoma | Advanced Malignant Solid Neoplasm ...
homologous recombination repair deficiency | elevated levels of B7-H4
-
qyjaswnpap(tjafwzykzy) = mfttesrsoz qwbeohpxvz (xdlmluiwkg )
-
14 Mar 2023
Phase 1
Ovarian Cancer | Breast Cancer | Prostatic Cancer ...
BRCA1 Mutation | BRCA2 Mutation | PALB2 Mutation ...
46
mzalhzuhvc(yarobnoqyw) = sbzympwkbe nczeblhixc (egkdekzxwl )
Positive
15 Jun 2022
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Core Patent

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Clinical Trial

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Approval

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Regulation

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