Last update 01 Nov 2024

Fexinidazole

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Fexinidazole Winthrop
Target-
Mechanism
DNA synthesis inhibitors
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (16 Jul 2021),
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC12H13N3O3S
InChIKeyMIWWSGDADVMLTG-UHFFFAOYSA-N
CAS Registry59729-37-2

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Trypanosomiasis, African
US
16 Jul 2021
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Trypanosomiasis, AfricanPhase 2
CG
10 Nov 2016
Trypanosomiasis, AfricanPhase 2
CG
10 Nov 2016
Trypanosomiasis, AfricanPhase 2
GN
10 Nov 2016
Trypanosomiasis, AfricanPhase 2
GN
10 Nov 2016
Trypanosomiasis, AfricanPhase 1
CG
10 Nov 2016
Trypanosomiasis, AfricanPhase 1
GN
10 Nov 2016
Trypanosomiasis, AfricanPhase 1
CG
10 Nov 2016
Trypanosomiasis, AfricanPhase 1
GN
10 Nov 2016
Heparin-induced thrombocytopeniaPhase 1
CG
01 Oct 2012
Heparin-induced thrombocytopeniaPhase 1
CF
01 Oct 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
174
(Inpatients)
minyywcqaf(gebsgudxzc) = yqmmewhonm kzhiorsuyb (yqmobeunje, xzqyuohtdw - ixaikehyya)
-
07 Jun 2024
(Outpatients)
minyywcqaf(gebsgudxzc) = mxnoqysgeu kzhiorsuyb (yqmobeunje, twdnuaqaxj - tafhtssnyb)
Phase 2/3
238
(qiscnxdwuc) = hshtdxwkyc gyjqpugeco (ryecvtmvez, 96.2 - 99.7)
-
01 Jul 2021
Phase 2/3
394
ojjdsoyqhr(nzygmxjdqv) = aueibqqyuz qaxgzmeskc (tkcocvjzkt )
Positive
13 Jan 2018
ojjdsoyqhr(nzygmxjdqv) = rrgiawywmg qaxgzmeskc (tkcocvjzkt )
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Approval

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Regulation

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