Last update 21 Nov 2024

Fexinidazole

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Fexinidazole Winthrop
Target-
Mechanism
DNA synthesis inhibitors
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (16 Jul 2021),
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC12H13N3O3S
InChIKeyMIWWSGDADVMLTG-UHFFFAOYSA-N
CAS Registry59729-37-2

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Trypanosomiasis, African
US
16 Jul 2021
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Heparin-induced thrombocytopeniaPhase 1
CF
01 Oct 2012
Trypanosomiasis, AfricanPreclinical
CG
10 Nov 2016
Trypanosomiasis, AfricanPreclinical
GN
10 Nov 2016
Trypanosomiasis, AfricanPreclinical
GN
10 Nov 2016
Trypanosomiasis, AfricanPreclinical
GN
10 Nov 2016
Trypanosomiasis, AfricanPreclinical
CG
10 Nov 2016
Trypanosomiasis, AfricanDiscovery
GN
10 Nov 2016
Trypanosomiasis, AfricanDiscovery
CG
10 Nov 2016
Trypanosomiasis, AfricanDiscovery
CG
10 Nov 2016
Heparin-induced thrombocytopeniaDiscovery
CG
01 Oct 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
174
(Inpatients)
rekoxjesfa(nzvsohldax) = mnewqyxfsa zcerqrljgz (uqrpdynoqi, ikungfqspa - znxpcbimbr)
-
07 Jun 2024
(Outpatients)
rekoxjesfa(nzvsohldax) = hbawuscbpk zcerqrljgz (uqrpdynoqi, gzzottthsx - hygfinmczr)
Phase 2/3
238
(pqbzzgnwgu) = cfsysjutqi suhrwmrlvc (lcciaygwoi, 96.2 - 99.7)
-
01 Jul 2021
Phase 2/3
394
wcecpqiabp(xkxcgafomv) = naintwcxln lbqhbsjtmv (wrfugfaigj )
Positive
13 Jan 2018
wcecpqiabp(xkxcgafomv) = ndemojbmkx lbqhbsjtmv (wrfugfaigj )
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Clinical Trial

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Approval

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Regulation

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